A Organ Weight phenotypic assay was performed on 2025 mice. The charts show the results of measuring Spleen weight in 9 female, 8 male mutants compared to 1019 female, 989 male controls. The mutants are for the Raver1em1(IMPC)Hmgu allele.
increased spleen weight
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P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Spleen weight | HMGU | Raver1em1(IMPC)Hmgu | homozygote | Early adult | HMGU_Raver1_Crispr1_AAES-1 | 4.87x10-3 | 2.45x10-4 | 1.94x10-5 |
Raver1 data charts
Spleen weightExperiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Spleen weight
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NCrl
Phenotyping center
HMGU
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Spleen weight / Box plot
Spleen weight / Scatter plot
Results of statistical analysis
Genotype P value
1.94x10-5
Genotype*Female P value
2.45x10-4
Genotype*Male P value
4.87x10-3
Classification
With phenotype threshold value 1e-04 - both sexes equally
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 1.94x10-5 |
Genotype parameter estimate | -0.028 |
Genotype standard error estimate | 0.004 |
Genotype Effect P Value | 1.94x10-5 |
Sex Parameter Estimate | -0.028 |
Sex Standard Error Estimate | 0.002 |
Sex Effect P Value | 1.94x10-5 |
Intercept Estimate | -0.019 |
Intercept Estimate Standard Error | 0.008 |
Sex Male KO P Value | 1.94x10-5 |
Sex Female KO P Value | 1.94x10-5 |
WT Residuals Normality Tests | 1.97x10-15 |
KO Residuals Normality Tests | 1.27x10-1 |
Statistical analysis API access
Experimental data download
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