increased spleen weight

  Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Spleen weightHMGURaver1em1(IMPC)HmguhomozygoteEarly adultHMGU_Raver1_Crispr1_AAES-14.87x10-32.45x10-41.94x10-5

Raver1 data charts

Spleen weight
Combination tested with the lowest p-value of 1.94x10-5
Experiments performed

A Organ Weight phenotypic assay was performed on 2025 mice. The charts show the results of measuring Spleen weight in 9 female, 8 male mutants compared to 1019 female, 989 male controls. The mutants are for the Raver1em1(IMPC)Hmgu allele.

Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Spleen weight
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NCrl
Phenotyping center
HMGU

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

Spleen weight / Box plot
Spleen weight / Scatter plot

Results of statistical analysis

Summary statistics of all data in the dataset

Statistical method

Batch effect significant true
Variance significant true
Genotype*Sex interaction effect p value 1.94x10-5
Genotype parameter estimate -0.028
Genotype standard error estimate 0.004
Genotype Effect P Value 1.94x10-5
Sex Parameter Estimate -0.028
Sex Standard Error Estimate 0.002
Sex Effect P Value 1.94x10-5
Intercept Estimate -0.019
Intercept Estimate Standard Error 0.008
Sex Male KO P Value 1.94x10-5
Sex Female KO P Value 1.94x10-5
WT Residuals Normality Tests 1.97x10-15
KO Residuals Normality Tests 1.27x10-1

Windowing parameters

View documentation about soft windowing
Sharpness (k) 5.426
Bandwidth (l)165

Experimental data download

Download data as:  

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