increased grip strength

Loading data

P-values equal or lower to 10^-4 (P < 0.0001) are marked as significant.



Forelimb and hindlimb grip strength measurement mean	BCM	Slc25a24^{tm1b(KOMP)Wtsi}	homozygote		Early adult	SLACB				2.21x10^-1	2.05x10^-5	2.05x10^-5

Slc25a24 data charts

Forelimb and hindlimb grip strength measurement mean

Combination tested with the lowest p-value of 2.05x10^-5

Experiments performed

A Grip Strength phenotypic assay was performed on 2680 mice. The charts show the results of measuring Forelimb and hindlimb grip strength measurement mean in 8 female, 8 male mutants compared to 1370 female, 1294 male controls. The mutants are for the Slc25a24^{tm1b(KOMP)Wtsi} allele.

Associated phenotype

increased grip strength

Zygosity

homozygote

Testing protocol

Grip Strength

Measured value

Forelimb and hindlimb grip strength measurement mean

Testing environment

Lab conditions and equipment

Life stage

Early adult

Background Strain

involves: C57BL/6N

Phenotyping center

BCM

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

Forelimb and hindlimb grip strength measurement mean / Box plot

Forelimb and hindlimb grip strength measurement mean / Scatter plot

Results of statistical analysis

Genotype P value

2.05x10^-5

Genotype*Female P value

2.05x10^-5

Genotype*Male P value

2.21x10^-1

Classification

Overally significant [level = 1e-04 , pvalue = 2.04564924509709e-05 ]; and with phenotype threshold value 1e-04 - females only

Summary statistics of all data in the dataset

Statistical method



Batch effect significant	true
Variance significant	true
Genotype*Sex interaction effect p value	2.05x10^-5
Genotype parameter estimate	-29.956
Genotype standard error estimate	10.637
Genotype Effect P Value	2.05x10^-5
Sex Parameter Estimate	-29.956
Sex Standard Error Estimate	3.853
Sex Effect P Value	2.05x10^-5
Intercept Estimate	153.687
Intercept Estimate Standard Error	12.819
Sex Male KO P Value	2.05x10^-5
Sex Female KO P Value	2.05x10^-5
WT Residuals Normality Tests	1.43x10^-3
KO Residuals Normality Tests	8.31x10^-1