increased circulating creatinine level

  Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
CreatinineMRC HarwellKlhdc2tm1b(EUCOMM)HmguheterozygoteEarly adultH-KLHDC2-G08-TM1B5.28x10-34.25x10-112.44x10-11

Klhdc2 data charts

Creatinine
Combination tested with the lowest p-value of 2.44x10-11
Experiments performed

A Clinical Chemistry phenotypic assay was performed on 4405 mice. The charts show the results of measuring Creatinine in 7 female, 7 male mutants compared to 2197 female, 2194 male controls. The mutants are for the Klhdc2tm1b(EUCOMM)Hmgu allele.

Associated phenotype
Zygosity
heterozygote
Testing protocol
Measured value
Creatinine
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NTac
Phenotyping center
MRC Harwell

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

Creatinine / Box plot
Creatinine / Scatter plot

Results of statistical analysis

Summary statistics of all data in the dataset

Statistical method

Batch effect significant true
Variance significant true
Genotype*Sex interaction effect p value 2.44x10-11
Genotype parameter estimate -0.016
Genotype standard error estimate 0.007
Genotype Effect P Value 2.44x10-11
Sex Parameter Estimate -0.016
Sex Standard Error Estimate 0.001
Sex Effect P Value 2.44x10-11
Intercept Estimate 0.119
Intercept Estimate Standard Error 0.001
Sex Male KO P Value 2.44x10-11
Sex Female KO P Value 2.44x10-11
WT Residuals Normality Tests 1.07x10-34
KO Residuals Normality Tests 1.43x10-4

Windowing parameters

View documentation about soft windowing
Sharpness (k) 1.177
Bandwidth (l)1930

Experimental data download

Download data as:  

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