A Clinical Chemistry phenotypic assay was performed on 4405 mice. The charts show the results of measuring Creatinine in 7 female, 7 male mutants compared to 2197 female, 2194 male controls. The mutants are for the Klhdc2tm1b(EUCOMM)Hmgu allele.
increased circulating creatinine level
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Creatinine | MRC Harwell | Klhdc2tm1b(EUCOMM)Hmgu | heterozygote | Early adult | H-KLHDC2-G08-TM1B | 5.28x10-3 | 4.25x10-11 | 2.44x10-11 |
Klhdc2 data charts
CreatinineExperiments performed
Associated phenotype
Zygosity
heterozygote
Testing protocol
Measured value
Creatinine
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NTac
Phenotyping center
MRC Harwell
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Creatinine / Box plot
Creatinine / Scatter plot
Results of statistical analysis
Genotype P value
2.44x10-11
Genotype*Female P value
4.25x10-11
Genotype*Male P value
5.28x10-3
Classification
Overally significant [level = 1e-04 , pvalue = 2.43540743127824e-11 ]; and with phenotype threshold value 1e-04 - different size as females greater
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 2.44x10-11 |
Genotype parameter estimate | -0.016 |
Genotype standard error estimate | 0.007 |
Genotype Effect P Value | 2.44x10-11 |
Sex Parameter Estimate | -0.016 |
Sex Standard Error Estimate | 0.001 |
Sex Effect P Value | 2.44x10-11 |
Intercept Estimate | 0.119 |
Intercept Estimate Standard Error | 0.001 |
Sex Male KO P Value | 2.44x10-11 |
Sex Female KO P Value | 2.44x10-11 |
WT Residuals Normality Tests | 1.07x10-34 |
KO Residuals Normality Tests | 1.43x10-4 |
Statistical analysis API access
Experimental data download
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