A Modified SHIRPA phenotypic assay was performed on 493 mice. The charts show the results of measuring Locomotor activity in 13 female, 11 male mutants compared to 185 female, 284 male controls. The mutants are for the Klhdc2tm1a(EUCOMM)Hmgu allele.
decreased locomotor activity
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Locomotor activity | MRC Harwell | Klhdc2tm1a(EUCOMM)Hmgu | heterozygote | Early adult | HEPD0523_4_G08 | 3.42x10-4 | 6.78x10-6 | 2.71x10-7 |
Klhdc2 data charts
Locomotor activityExperiments performed
Associated phenotype
Zygosity
heterozygote
Testing protocol
Measured value
Locomotor activity
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NTac
Phenotyping center
MRC Harwell
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Locomotor activity / Box plot
Locomotor activity / Scatter plot
Results of statistical analysis
Genotype P value
2.71x10-7
Genotype*Female P value
6.78x10-6
Genotype*Male P value
3.42x10-4
Classification
With phenotype threshold value 1e-04 - both sexes equally
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 2.71x10-7 |
Genotype parameter estimate | N/A |
Genotype standard error estimate | 1.330 |
Genotype Effect P Value | 2.71x10-7 |
Sex Parameter Estimate | N/A |
Sex Standard Error Estimate | N/A |
Sex Effect P Value | 2.71x10-7 |
Intercept Estimate | 24.930 |
Intercept Estimate Standard Error | 2.380 |
Sex Male KO P Value | 2.71x10-7 |
Sex Female KO P Value | 2.71x10-7 |
WT Residuals Normality Tests | 5.26x10-4 |
KO Residuals Normality Tests | 8.75x10-1 |
Statistical analysis API access
Experimental data download
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