decreased locomotor activity

  Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Locomotor activityMRC HarwellKlhdc2tm1a(EUCOMM)HmguheterozygoteEarly adultHEPD0523_4_G083.42x10-46.78x10-62.71x10-7

Klhdc2 data charts

Locomotor activity
Combination tested with the lowest p-value of 2.71x10-7
Experiments performed

A Modified SHIRPA phenotypic assay was performed on 493 mice. The charts show the results of measuring Locomotor activity in 13 female, 11 male mutants compared to 185 female, 284 male controls. The mutants are for the Klhdc2tm1a(EUCOMM)Hmgu allele.

Associated phenotype
Zygosity
heterozygote
Testing protocol
Measured value
Locomotor activity
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NTac
Phenotyping center
MRC Harwell

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

Locomotor activity / Box plot
Locomotor activity / Scatter plot

Results of statistical analysis

Summary statistics of all data in the dataset

Statistical method

Batch effect significant true
Variance significant true
Genotype*Sex interaction effect p value 2.71x10-7
Genotype parameter estimate N/A
Genotype standard error estimate 1.330
Genotype Effect P Value 2.71x10-7
Sex Parameter Estimate N/A
Sex Standard Error Estimate N/A
Sex Effect P Value 2.71x10-7
Intercept Estimate 24.930
Intercept Estimate Standard Error 2.380
Sex Male KO P Value 2.71x10-7
Sex Female KO P Value 2.71x10-7
WT Residuals Normality Tests 5.26x10-4
KO Residuals Normality Tests 8.75x10-1

Windowing parameters

View documentation about soft windowing
Sharpness (k) 1.107
Bandwidth (l)858

Experimental data download

Download data as:  

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter