increased neutrophil cell number

  Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Neutrophil cell countMRC HarwellKlhdc2tm1b(EUCOMM)HmguheterozygoteEarly adultH-KLHDC2-G08-TM1B1.8x10-143.67x10-14.24x10-1
Neutrophil differential countMRC HarwellKlhdc2tm1b(EUCOMM)HmguheterozygoteEarly adultH-KLHDC2-G08-TM1B8.38x10-208.01x10-19.61x10-1

Klhdc2 data charts

Neutrophil cell count
Combination tested with the lowest p-value of 1.8x10-14
Experiments performed

A Hematology phenotypic assay was performed on 421 mice. The charts show the results of measuring Neutrophil cell count in 8 female, 7 male mutants compared to 207 female, 199 male controls. The mutants are for the Klhdc2tm1b(EUCOMM)Hmgu allele.

Associated phenotype
Zygosity
heterozygote
Testing protocol
Measured value
Neutrophil cell count
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NTac
Phenotyping center
MRC Harwell

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

Neutrophil cell count / Box plot
Neutrophil cell count / Scatter plot

Results of statistical analysis

Summary statistics of all data in the dataset

Statistical method

Batch effect significant false
Variance significant true
Genotype*Sex interaction effect p value 4.24x10-1
Genotype parameter estimate 0.169
Genotype standard error estimate 0.125
Genotype Effect P Value 4.24x10-1
Sex Parameter Estimate 0.169
Sex Standard Error Estimate 0.039
Sex Effect P Value 4.24x10-1
Intercept Estimate 0.507
Intercept Estimate Standard Error 0.027
Sex Male KO P Value 4.24x10-1
Sex Female KO P Value 4.24x10-1
WT Residuals Normality Tests 9.42x10-30
KO Residuals Normality Tests 1.08x10-3

Windowing parameters

View documentation about soft windowing
Sharpness (k) 1.177
Bandwidth (l)48

Experimental data download

Download data as:  

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