A Acoustic Startle and Pre-pulse Inhibition (PPI) phenotypic assay was performed on 2412 mice. The charts show the results of measuring Response amplitude - S in 8 female, 8 male mutants compared to 1220 female, 1176 male controls. The mutants are for the Paqr6tm1b(KOMP)Wtsi allele.
increased startle reflex
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Response amplitude - S | BCM | Paqr6tm1b(KOMP)Wtsi | homozygote | Early adult | Paqr6 <EPD0490_5_C10>-1 | 1.31x10-4 | 3.48x10-2 | 4.19x10-5 |
Paqr6 data charts
Response amplitude - SExperiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Response amplitude - S
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6N
Phenotyping center
BCM
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Response amplitude - S / Box plot
Response amplitude - S / Scatter plot
Results of statistical analysis
Genotype P value
4.19x10-5
Genotype*Female P value
3.48x10-2
Genotype*Male P value
1.31x10-4
Classification
With phenotype threshold value 1e-04 - both sexes equally
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 4.19x10-5 |
Genotype parameter estimate | 266.161 |
Genotype standard error estimate | 115.505 |
Genotype Effect P Value | 4.19x10-5 |
Sex Parameter Estimate | 266.161 |
Sex Standard Error Estimate | 19.614 |
Sex Effect P Value | 4.19x10-5 |
Intercept Estimate | 425.523 |
Intercept Estimate Standard Error | 15.394 |
Sex Male KO P Value | 4.19x10-5 |
Sex Female KO P Value | 4.19x10-5 |
WT Residuals Normality Tests | 1.16x10-42 |
KO Residuals Normality Tests | 2.52x10-1 |
Statistical analysis API access
Experimental data download
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