increased cornea thickness

  Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Left corneal thicknessBCMPpfia4em1(IMPC)BayhomozygoteEarly adultPPFFB8.52x10-15.11x10-95.11x10-9

Ppfia4 data charts

Left corneal thickness
Combination tested with the lowest p-value of 5.11x10-9
Experiments performed

A Eye Morphology phenotypic assay was performed on 1767 mice. The charts show the results of measuring Left corneal thickness in 9 female, 7 male mutants compared to 894 female, 857 male controls. The mutants are for the Ppfia4em1(IMPC)Bay allele.

Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Left corneal thickness
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6N
Phenotyping center
BCM

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

Left corneal thickness / Box plot
Left corneal thickness / Scatter plot

Results of statistical analysis

Summary statistics of all data in the dataset

Statistical method

Batch effect significant true
Variance significant true
Genotype*Sex interaction effect p value 5.11x10-9
Genotype parameter estimate -0.657
Genotype standard error estimate 5.345
Genotype Effect P Value 5.11x10-9
Sex Parameter Estimate -0.657
Sex Standard Error Estimate 0.958
Sex Effect P Value 5.11x10-9
Intercept Estimate 102.642
Intercept Estimate Standard Error 0.771
Sex Male KO P Value 5.11x10-9
Sex Female KO P Value 5.11x10-9
WT Residuals Normality Tests 7.35x10-44
KO Residuals Normality Tests 6.62x10-4

Windowing parameters

View documentation about soft windowing
Sharpness (k) 2.040
Bandwidth (l)398

Experimental data download

Download data as:  

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