A Eye Morphology phenotypic assay was performed on 1767 mice. The charts show the results of measuring Left corneal thickness in 9 female, 7 male mutants compared to 894 female, 857 male controls. The mutants are for the Ppfia4em1(IMPC)Bay allele.
increased cornea thickness
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Left corneal thickness | BCM | Ppfia4em1(IMPC)Bay | homozygote | Early adult | PPFFB | 8.52x10-1 | 5.11x10-9 | 5.11x10-9 |
Ppfia4 data charts
Left corneal thicknessExperiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Left corneal thickness
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6N
Phenotyping center
BCM
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Left corneal thickness / Box plot
Left corneal thickness / Scatter plot
Results of statistical analysis
Genotype P value
5.11x10-9
Genotype*Female P value
5.11x10-9
Genotype*Male P value
8.52x10-1
Classification
Overally significant [level = 1e-04 , pvalue = 5.11211428744218e-09 ]; and with phenotype threshold value 1e-04 - females only
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 5.11x10-9 |
Genotype parameter estimate | -0.657 |
Genotype standard error estimate | 5.345 |
Genotype Effect P Value | 5.11x10-9 |
Sex Parameter Estimate | -0.657 |
Sex Standard Error Estimate | 0.958 |
Sex Effect P Value | 5.11x10-9 |
Intercept Estimate | 102.642 |
Intercept Estimate Standard Error | 0.771 |
Sex Male KO P Value | 5.11x10-9 |
Sex Female KO P Value | 5.11x10-9 |
WT Residuals Normality Tests | 7.35x10-44 |
KO Residuals Normality Tests | 6.62x10-4 |
Statistical analysis API access
Experimental data download
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