dilated aorta

  Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Aortic diameter (Dao)HMGULsm1tm1b(EUCOMM)HmguheterozygoteEarly adultHMGU-HEPD0702_3_G05-1-13.29x10-104.41x10-101.33x10-14
Aortic diameter (Dao)HMGULsm1tm1b(EUCOMM)HmguhomozygoteEarly adultHMGU-HEPD0702_3_G05-1-13.32x10-5

Lsm1 data charts

Aortic diameter (Dao)
Combination tested with the lowest p-value of 1.33x10-14
Experiments performed

A Echo phenotypic assay was performed on 1698 mice. The charts show the results of measuring Aortic diameter (Dao) in 8 female, 8 male mutants compared to 847 female, 835 male controls. The mutants are for the Lsm1tm1b(EUCOMM)Hmgu allele.

Associated phenotype
Zygosity
heterozygote
Testing protocol
Measured value
Aortic diameter (Dao)
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NTac
Phenotyping center
HMGU

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

Aortic diameter (Dao) / Box plot
Aortic diameter (Dao) / Scatter plot

Results of statistical analysis

Summary statistics of all data in the dataset

Statistical method

Batch effect significant true
Variance significant true
Genotype*Sex interaction effect p value 1.33x10-14
Genotype parameter estimate N/A
Genotype standard error estimate 0.033
Genotype Effect P Value 1.33x10-14
Sex Parameter Estimate N/A
Sex Standard Error Estimate N/A
Sex Effect P Value 1.33x10-14
Intercept Estimate 1.024
Intercept Estimate Standard Error 0.053
Sex Male KO P Value 1.33x10-14
Sex Female KO P Value 1.33x10-14
WT Residuals Normality Tests 7.69x10-4
KO Residuals Normality Tests 9.96x10-1

Windowing parameters

View documentation about soft windowing
Sharpness (k) 8.324
Bandwidth (l)114

Experimental data download

Download data as:  

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