A Electrocardiogram (ECG) phenotypic assay was performed on 1862 mice. The charts show the results of measuring HRV in 8 female, 4 male mutants compared to 914 female, 936 male controls. The mutants are for the Lsm1tm1b(EUCOMM)Hmgu allele.
increased heart rate variability
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
HRV | HMGU | Lsm1tm1b(EUCOMM)Hmgu | homozygote | Early adult | HMGU-HEPD0702_3_G05-1-1 | 4.19x10-7 | 3.74x10-1 | 3.74x10-1 | |
HRV | HMGU | Lsm1tm1b(EUCOMM)Hmgu | heterozygote | Early adult | HMGU-HEPD0702_3_G05-1-1 | 1.38x10-6 | 5.71x10-1 | 5.65x10-1 |
Lsm1 data charts
HRVExperiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
HRV
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NTac
Phenotyping center
HMGU
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
HRV / Box plot
HRV / Scatter plot
Results of statistical analysis
Genotype P value
3.74x10-1
Genotype*Female P value
3.74x10-1
Genotype*Male P value
4.19x10-7
Classification
Overally insignificant [level = 1e-04 , pvalue = 0.373935032094593 ]; but with phenotype threshold value 1e-04 - males only
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | false |
Variance significant | true |
Genotype*Sex interaction effect p value | 3.74x10-1 |
Genotype parameter estimate | -4.958 |
Genotype standard error estimate | 6.226 |
Genotype Effect P Value | 3.74x10-1 |
Sex Parameter Estimate | -4.958 |
Sex Standard Error Estimate | 1.037 |
Sex Effect P Value | 3.74x10-1 |
Intercept Estimate | 15.388 |
Intercept Estimate Standard Error | 0.743 |
Sex Male KO P Value | 3.74x10-1 |
Sex Female KO P Value | 3.74x10-1 |
WT Residuals Normality Tests | 9.62x10-48 |
KO Residuals Normality Tests | 1.67x10-3 |
Statistical analysis API access
Experimental data download
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