decreased locomotor activity

  Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Center distance travelledHMGULsm1tm1b(EUCOMM)HmguhomozygoteEarly adultHMGU-HEPD0702_3_G05-1-16.73x10-32.57x10-42.35x10-5

Lsm1 data charts

Center distance travelled
Combination tested with the lowest p-value of 2.35x10-5
Experiments performed

A Open Field phenotypic assay was performed on 1799 mice. The charts show the results of measuring Center distance travelled in 7 female, 4 male mutants compared to 874 female, 914 male controls. The mutants are for the Lsm1tm1b(EUCOMM)Hmgu allele.

Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Center distance travelled
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NTac
Phenotyping center
HMGU

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

Center distance travelled / Box plot
Center distance travelled / Scatter plot

Results of statistical analysis

Summary statistics of all data in the dataset

Statistical method

Batch effect significant true
Variance significant true
Genotype*Sex interaction effect p value 2.35x10-5
Genotype parameter estimate N/A
Genotype standard error estimate 888.495
Genotype Effect P Value 2.35x10-5
Sex Parameter Estimate N/A
Sex Standard Error Estimate N/A
Sex Effect P Value 2.35x10-5
Intercept Estimate 9524.078
Intercept Estimate Standard Error 156.422
Sex Male KO P Value 2.35x10-5
Sex Female KO P Value 2.35x10-5
WT Residuals Normality Tests 5.89x10-2
KO Residuals Normality Tests 4.81x10-1

Windowing parameters

View documentation about soft windowing
Sharpness (k) 2.305
Bandwidth (l)418

Experimental data download

Download data as:  

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter