A Eye Morphology phenotypic assay was performed on 1997 mice. The charts show the results of measuring Lens in 8 female, 4 male mutants compared to 975 female, 1010 male controls. The mutants are for the Lsm1tm1b(EUCOMM)Hmgu allele.
abnormal lens morphology
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Lens | HMGU | Lsm1tm1b(EUCOMM)Hmgu | homozygote | Early adult | HMGU-HEPD0702_3_G05-1-1 | 1.21x10-5 | 9.53x10-4 | 7.63x10-8 | |
Min right eye lens density | HMGU | Lsm1tm1b(EUCOMM)Hmgu | heterozygote | Early adult | HMGU-HEPD0702_3_G05-1-1 | 1.82x10-4 | 7.27x10-4 | 4.89x10-6 | |
Mean right eye lens density | HMGU | Lsm1tm1b(EUCOMM)Hmgu | heterozygote | Early adult | HMGU-HEPD0702_3_G05-1-1 | 1.35x10-4 | 1.22x10-3 | 1.1x10-5 | |
Mean left eye lens density | HMGU | Lsm1tm1b(EUCOMM)Hmgu | heterozygote | Early adult | HMGU-HEPD0702_3_G05-1-1 | 9.6x10-4 | 3.2x10-4 | 1.35x10-5 |
Lsm1 data charts
LensExperiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Lens
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NTac
Phenotyping center
HMGU
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Results of statistical analysis
Combined Male and Female P value
7.63x10-8
Males only
1.21x10-5
Females only
9.53x10-4
Classification
With phenotype threshold value 1e-04 - significant in males and in combined dataset
Counts by sample type
Statistical method
Fisher Exact Test framework
Statistical analysis API access
Experimental data download
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