A Acoustic Startle and Pre-pulse Inhibition (PPI) phenotypic assay was performed on 2820 mice. The charts show the results of measuring % Pre-pulse inhibition - PPI1 in 8 female, 8 male mutants compared to 1399 female, 1405 male controls. The mutants are for the Erlec1em1(IMPC)Mbp allele.
increased prepulse inhibition
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
% Pre-pulse inhibition - PPI1 | UC Davis | Erlec1em1(IMPC)Mbp | homozygote | Early adult | CR1526 | 1.2x10-4 | 1.99x10-3 | 3.74x10-6 | |
% Pre-pulse inhibition - Global | UC Davis | Erlec1em1(IMPC)Mbp | homozygote | Early adult | CR1526 | 1x10-4 | 2.31x10-2 | 4.59x10-5 |
Erlec1 data charts
% Pre-pulse inhibition - PPI1Experiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
% Pre-pulse inhibition - PPI1
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NCrl
Phenotyping center
UC Davis
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Statistical information
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 3.74x10-6 |
Genotype parameter estimate | N/A |
Genotype standard error estimate | 5.300 |
Genotype Effect P Value | 3.74x10-6 |
Sex Parameter Estimate | N/A |
Sex Standard Error Estimate | N/A |
Sex Effect P Value | 3.74x10-6 |
Intercept Estimate | 46.932 |
Intercept Estimate Standard Error | 3.192 |
Sex Male KO P Value | 3.74x10-6 |
Sex Female KO P Value | 3.74x10-6 |
WT Residuals Normality Tests | 1.46x10-2 |
KO Residuals Normality Tests | 5.01x10-1 |