decreased neutrophil cell number

Loading data

P-values equal or lower to 10^-4 (P < 0.0001) are marked as significant.



Neutrophil differential count	MRC Harwell	Synj1^{tm1b(EUCOMM)Wtsi}	heterozygote		Early adult	H-SYNJ1-C03-TM1B				1.19x10^-15	9.55x10^-1	9.68x10^-1

Synj1 data charts

Neutrophil differential count

Combination tested with the lowest p-value of 1.19x10^-15

Experiments performed

A Hematology phenotypic assay was performed on 780 mice. The charts show the results of measuring Neutrophil differential count in 8 female, 8 male mutants compared to 382 female, 382 male controls. The mutants are for the Synj1^{tm1b(EUCOMM)Wtsi} allele.

Associated phenotype

decreased neutrophil cell number

Zygosity

heterozygote

Testing protocol

Hematology

Measured value

Neutrophil differential count

Testing environment

Lab conditions and equipment

Life stage

Early adult

Background Strain

involves: C57BL/6NTac

Phenotyping center

MRC Harwell

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

Neutrophil differential count / Box plot

Neutrophil differential count / Scatter plot

Results of statistical analysis

Genotype P value

9.68x10^-1

Genotype*Female P value

9.55x10^-1

Genotype*Male P value

1.19x10^-15

Classification

Overally insignificant [level = 1e-04 , pvalue = 0.967699033223589 ]; but with phenotype threshold value 1e-04 - males only

Summary statistics of all data in the dataset

Statistical method



Batch effect significant	true
Variance significant	true
Genotype*Sex interaction effect p value	9.68x10^-1
Genotype parameter estimate	1.254
Genotype standard error estimate	2.093
Genotype Effect P Value	9.68x10^-1
Sex Parameter Estimate	1.254
Sex Standard Error Estimate	0.573
Sex Effect P Value	9.68x10^-1
Intercept Estimate	9.559
Intercept Estimate Standard Error	0.673
Sex Male KO P Value	9.68x10^-1
Sex Female KO P Value	9.68x10^-1
WT Residuals Normality Tests	4.03x10^-23
KO Residuals Normality Tests	1.04x10^-1