A Clinical Chemistry phenotypic assay was performed on 4103 mice. The charts show the results of measuring Urea (Blood Urea Nitrogen - BUN) in 7 female, 7 male mutants compared to 2038 female, 2051 male controls. The mutants are for the Usp21tm1a(EUCOMM)Wtsi allele.
decreased blood urea nitrogen level
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Urea (Blood Urea Nitrogen - BUN) | WTSI | Usp21tm1a(EUCOMM)Wtsi | homozygote | Early adult | MECN | 1.8x10-4 | 4.33x10-4 | 4.21x10-6 |
Usp21 data charts
Urea (Blood Urea Nitrogen - BUN)Experiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Urea (Blood Urea Nitrogen - BUN)
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6N
Phenotyping center
WTSI
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Urea (Blood Urea Nitrogen - BUN) / Box plot
Urea (Blood Urea Nitrogen - BUN) / Scatter plot
Results of statistical analysis
Genotype P value
4.21x10-6
Genotype*Female P value
4.33x10-4
Genotype*Male P value
1.8x10-4
Classification
With phenotype threshold value 1e-04 - both sexes equally
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 4.21x10-6 |
Genotype parameter estimate | N/A |
Genotype standard error estimate | 1.034 |
Genotype Effect P Value | 4.21x10-6 |
Sex Parameter Estimate | N/A |
Sex Standard Error Estimate | N/A |
Sex Effect P Value | 4.21x10-6 |
Intercept Estimate | 22.734 |
Intercept Estimate Standard Error | 0.933 |
Sex Male KO P Value | 4.21x10-6 |
Sex Female KO P Value | 4.21x10-6 |
WT Residuals Normality Tests | 4.94x10-8 |
KO Residuals Normality Tests | 2.25x10-1 |
Statistical analysis API access
Experimental data download
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