A Hematology phenotypic assay was performed on 3034 mice. The charts show the results of measuring White blood cell count in 7 female, 7 male mutants compared to 1524 female, 1496 male controls. The mutants are for the Usp21tm1a(EUCOMM)Wtsi allele.
increased leukocyte cell number
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P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
White blood cell count | WTSI | Usp21tm1a(EUCOMM)Wtsi | homozygote | Early adult | MECN | 3.87x10-7 | 3.02x10-1 | 3.41x10-1 |
Usp21 data charts
White blood cell countExperiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
White blood cell count
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6N
Phenotyping center
WTSI
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
White blood cell count / Box plot
White blood cell count / Scatter plot
Results of statistical analysis
Genotype P value
3.41x10-1
Genotype*Female P value
3.02x10-1
Genotype*Male P value
3.87x10-7
Classification
Overally insignificant [level = 1e-04 , pvalue = 0.340674793725924 ]; but with phenotype threshold value 1e-04 - males only
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 3.41x10-1 |
Genotype parameter estimate | 1.629 |
Genotype standard error estimate | 0.565 |
Genotype Effect P Value | 3.41x10-1 |
Sex Parameter Estimate | 1.629 |
Sex Standard Error Estimate | 0.105 |
Sex Effect P Value | 3.41x10-1 |
Intercept Estimate | 6.275 |
Intercept Estimate Standard Error | 0.093 |
Sex Male KO P Value | 3.41x10-1 |
Sex Female KO P Value | 3.41x10-1 |
WT Residuals Normality Tests | 2.12x10-14 |
KO Residuals Normality Tests | 1.2x10-1 |
Statistical analysis API access
Experimental data download
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