A Grip Strength phenotypic assay was performed on 1592 mice. The charts show the results of measuring Forelimb grip strength normalised against body weight in 8 female, 8 male mutants compared to 806 female, 770 male controls. The mutants are for the Iqgap1tm1b(EUCOMM)Wtsi allele.
increased grip strength
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Forelimb grip strength normalised against body weight | TCP | Iqgap1tm1b(EUCOMM)Wtsi | homozygote | Early adult | TCPA0985Cre | 6.69x10-6 | 5.75x10-3 | 6.74x10-3 | |
Forelimb and hindlimb grip strength normalised against body weight | TCP | Iqgap1tm1b(EUCOMM)Wtsi | homozygote | Early adult | TCPA0985Cre | 8.97x10-6 | 2.04x10-1 | 2.06x10-1 |
Iqgap1 data charts
Forelimb grip strength normalised against body weightExperiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Forelimb grip strength normalised against body weight
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NCrl
Phenotyping center
TCP
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Forelimb grip strength normalised against body weight / Box plot
Forelimb grip strength normalised against body weight / Scatter plot
Results of statistical analysis
Genotype P value
6.74x10-3
Genotype*Female P value
5.75x10-3
Genotype*Male P value
6.69x10-6
Classification
Overally insignificant [level = 1e-04 , pvalue = 0.00674052332293273 ]; but with phenotype threshold value 1e-04 - different size as males greater
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 6.74x10-3 |
Genotype parameter estimate | -0.936 |
Genotype standard error estimate | 0.229 |
Genotype Effect P Value | 6.74x10-3 |
Sex Parameter Estimate | -0.936 |
Sex Standard Error Estimate | 0.057 |
Sex Effect P Value | 6.74x10-3 |
Intercept Estimate | 5.343 |
Intercept Estimate Standard Error | 0.048 |
Sex Male KO P Value | 6.74x10-3 |
Sex Female KO P Value | 6.74x10-3 |
WT Residuals Normality Tests | 6.76x10-1 |
KO Residuals Normality Tests | 1.38x10-2 |
Statistical analysis API access
Experimental data download
Download data as: