increased lymphocyte cell number

  Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Lymphocyte cell countTCPIqgap1tm1b(EUCOMM)WtsihomozygoteEarly adultTCPA0985Cre5.52x10-144.1x10-67.34x10-6

Iqgap1 data charts

Lymphocyte cell count
Combination tested with the lowest p-value of 5.52x10-14
Experiments performed

A Hematology phenotypic assay was performed on 765 mice. The charts show the results of measuring Lymphocyte cell count in 4 female, 8 male mutants compared to 401 female, 352 male controls. The mutants are for the Iqgap1tm1b(EUCOMM)Wtsi allele.

Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Lymphocyte cell count
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NCrl
Phenotyping center
TCP

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

Lymphocyte cell count / Box plot
Lymphocyte cell count / Scatter plot

Results of statistical analysis

Summary statistics of all data in the dataset

Statistical method

Batch effect significant true
Variance significant true
Genotype*Sex interaction effect p value 7.34x10-6
Genotype parameter estimate 1.136
Genotype standard error estimate 1.157
Genotype Effect P Value 7.34x10-6
Sex Parameter Estimate 1.136
Sex Standard Error Estimate 0.148
Sex Effect P Value 7.34x10-6
Intercept Estimate 7.546
Intercept Estimate Standard Error 0.176
Sex Male KO P Value 7.34x10-6
Sex Female KO P Value 7.34x10-6
WT Residuals Normality Tests 2x10-4
KO Residuals Normality Tests 8.41x10-2

Windowing parameters

View documentation about soft windowing
Sharpness (k) 2.305
Bandwidth (l)644

Experimental data download

Download data as:  

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter