A Hematology phenotypic assay was performed on 765 mice. The charts show the results of measuring Lymphocyte cell count in 4 female, 8 male mutants compared to 401 female, 352 male controls. The mutants are for the Iqgap1tm1b(EUCOMM)Wtsi allele.
increased lymphocyte cell number
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Lymphocyte cell count | TCP | Iqgap1tm1b(EUCOMM)Wtsi | homozygote | Early adult | TCPA0985Cre | 5.52x10-14 | 4.1x10-6 | 7.34x10-6 |
Iqgap1 data charts
Lymphocyte cell countExperiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Lymphocyte cell count
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NCrl
Phenotyping center
TCP
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Lymphocyte cell count / Box plot
Lymphocyte cell count / Scatter plot
Results of statistical analysis
Genotype P value
7.34x10-6
Genotype*Female P value
4.1x10-6
Genotype*Male P value
5.52x10-14
Classification
Overally significant [level = 1e-04 , pvalue = 7.3415272865418e-06 ]; and with phenotype threshold value 1e-04 - different size as males greater
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 7.34x10-6 |
Genotype parameter estimate | 1.136 |
Genotype standard error estimate | 1.157 |
Genotype Effect P Value | 7.34x10-6 |
Sex Parameter Estimate | 1.136 |
Sex Standard Error Estimate | 0.148 |
Sex Effect P Value | 7.34x10-6 |
Intercept Estimate | 7.546 |
Intercept Estimate Standard Error | 0.176 |
Sex Male KO P Value | 7.34x10-6 |
Sex Female KO P Value | 7.34x10-6 |
WT Residuals Normality Tests | 2x10-4 |
KO Residuals Normality Tests | 8.41x10-2 |
Statistical analysis API access
Experimental data download
Download data as: