A X-ray phenotypic assay was performed on 335 mice. The charts show the results of measuring Tibia length in 5 female, 5 male mutants compared to 173 female, 152 male controls. The mutants are for the Iqgap1tm1b(EUCOMM)Wtsi allele.
short tibia
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P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Tibia length | TCP | Iqgap1tm1b(EUCOMM)Wtsi | homozygote | Early adult | TCPA0985Cre | 6.41x10-8 | 3.54x10-16 | 1.89x10-13 |
Iqgap1 data charts
Tibia lengthExperiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Tibia length
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NCrl
Phenotyping center
TCP
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Tibia length / Box plot
Tibia length / Scatter plot
Results of statistical analysis
Genotype P value
1.89x10-13
Genotype*Female P value
3.54x10-16
Genotype*Male P value
6.41x10-8
Classification
Overally significant [level = 1e-04 , pvalue = 1.88737914186277e-13 ]; and with phenotype threshold value 1e-04 - different size as females greater
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 1.89x10-13 |
Genotype parameter estimate | -0.279 |
Genotype standard error estimate | 0.106 |
Genotype Effect P Value | 1.89x10-13 |
Sex Parameter Estimate | -0.279 |
Sex Standard Error Estimate | 0.044 |
Sex Effect P Value | 1.89x10-13 |
Intercept Estimate | 16.883 |
Intercept Estimate Standard Error | 0.158 |
Sex Male KO P Value | 1.89x10-13 |
Sex Female KO P Value | 1.89x10-13 |
WT Residuals Normality Tests | 1.71x10-1 |
KO Residuals Normality Tests | 3.94x10-1 |
Statistical analysis API access
Experimental data download
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