A Combined SHIRPA and Dysmorphology phenotypic assay was performed on 1604 mice. The charts show the results of measuring Locomotor activity in 8 female, 8 male mutants compared to 814 female, 774 male controls. The mutants are for the Iqgap1tm1b(EUCOMM)Wtsi allele.
decreased exploration in new environment
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Locomotor activity | TCP | Iqgap1tm1b(EUCOMM)Wtsi | homozygote | Early adult | TCPA0985Cre | 4.97x10-4 | 7.73x10-3 | 2.94x10-5 |
Iqgap1 data charts
Locomotor activityExperiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Locomotor activity
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NCrl
Phenotyping center
TCP
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Locomotor activity / Box plot
Locomotor activity / Scatter plot
Results of statistical analysis
Genotype P value
2.94x10-5
Genotype*Female P value
7.73x10-3
Genotype*Male P value
4.97x10-4
Classification
With phenotype threshold value 1e-04 - both sexes equally
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 2.94x10-5 |
Genotype parameter estimate | -3.503 |
Genotype standard error estimate | 2.271 |
Genotype Effect P Value | 2.94x10-5 |
Sex Parameter Estimate | -3.503 |
Sex Standard Error Estimate | 0.517 |
Sex Effect P Value | 2.94x10-5 |
Intercept Estimate | 25.072 |
Intercept Estimate Standard Error | 0.410 |
Sex Male KO P Value | 2.94x10-5 |
Sex Female KO P Value | 2.94x10-5 |
WT Residuals Normality Tests | 2.43x10-5 |
KO Residuals Normality Tests | 2.53x10-1 |
Statistical analysis API access
Experimental data download
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