increased circulating alkaline phosphatase level

  Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Alkaline phosphataseJAXMpripem1(IMPC)JheterozygoteEarly adultJR319107.13x10-21.17x10-51.17x10-5

Mprip data charts

Alkaline phosphatase
Combination tested with the lowest p-value of 1.17x10-5
Experiments performed

A Clinical Chemistry phenotypic assay was performed on 2956 mice. The charts show the results of measuring Alkaline phosphatase in 4 female, 6 male mutants compared to 1489 female, 1457 male controls. The mutants are for the Mpripem1(IMPC)J allele.

Associated phenotype
Zygosity
heterozygote
Testing protocol
Measured value
Alkaline phosphatase
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NJ
Phenotyping center
JAX

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

Alkaline phosphatase / Box plot
Alkaline phosphatase / Scatter plot

Results of statistical analysis

Summary statistics of all data in the dataset

Statistical method

Batch effect significant true
Variance significant true
Genotype*Sex interaction effect p value 1.17x10-5
Genotype parameter estimate -25.776
Genotype standard error estimate 5.768
Genotype Effect P Value 1.17x10-5
Sex Parameter Estimate -25.776
Sex Standard Error Estimate 0.931
Sex Effect P Value 1.17x10-5
Intercept Estimate 112.971
Intercept Estimate Standard Error 2.665
Sex Male KO P Value 1.17x10-5
Sex Female KO P Value 1.17x10-5
WT Residuals Normality Tests 2.08x10-15
KO Residuals Normality Tests 9.18x10-1

Windowing parameters

View documentation about soft windowing
Sharpness (k) 8.324
Bandwidth (l)853

Experimental data download

Download data as:  

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter