A Clinical Chemistry phenotypic assay was performed on 2956 mice. The charts show the results of measuring Alkaline phosphatase in 4 female, 6 male mutants compared to 1489 female, 1457 male controls. The mutants are for the Mpripem1(IMPC)J allele.
increased circulating alkaline phosphatase level
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Alkaline phosphatase | JAX | Mpripem1(IMPC)J | heterozygote | Early adult | JR31910 | 7.13x10-2 | 1.17x10-5 | 1.17x10-5 |
Mprip data charts
Alkaline phosphataseExperiments performed
Associated phenotype
Zygosity
heterozygote
Testing protocol
Measured value
Alkaline phosphatase
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NJ
Phenotyping center
JAX
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Alkaline phosphatase / Box plot
Alkaline phosphatase / Scatter plot
Results of statistical analysis
Genotype P value
1.17x10-5
Genotype*Female P value
1.17x10-5
Genotype*Male P value
7.13x10-2
Classification
Overally significant [level = 1e-04 , pvalue = 1.17311618512694e-05 ]; and with phenotype threshold value 1e-04 - females only
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 1.17x10-5 |
Genotype parameter estimate | -25.776 |
Genotype standard error estimate | 5.768 |
Genotype Effect P Value | 1.17x10-5 |
Sex Parameter Estimate | -25.776 |
Sex Standard Error Estimate | 0.931 |
Sex Effect P Value | 1.17x10-5 |
Intercept Estimate | 112.971 |
Intercept Estimate Standard Error | 2.665 |
Sex Male KO P Value | 1.17x10-5 |
Sex Female KO P Value | 1.17x10-5 |
WT Residuals Normality Tests | 2.08x10-15 |
KO Residuals Normality Tests | 9.18x10-1 |
Statistical analysis API access
Experimental data download
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