decreased prepulse inhibition

  Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
% Pre-pulse inhibition - PPI3BCMArhgap31em1(IMPC)BayheterozygoteEarly adultARHTB2.23x10-67.34x10-17.34x10-1
% Pre-pulse inhibition - GlobalBCMArhgap31em1(IMPC)BayheterozygoteEarly adultARHTB7.54x10-89.18x10-19.18x10-1
% Pre-pulse inhibition - PPI2BCMArhgap31em1(IMPC)BayheterozygoteEarly adultARHTB2.53x10-109.25x10-19.25x10-1

Arhgap31 data charts

% Pre-pulse inhibition - PPI3
Combination tested with the lowest p-value of 2.23x10-6
Experiments performed

A Acoustic Startle and Pre-pulse Inhibition (PPI) phenotypic assay was performed on 2408 mice. The charts show the results of measuring % Pre-pulse inhibition - PPI3 in 8 female, 9 male mutants compared to 1217 female, 1174 male controls. The mutants are for the Arhgap31em1(IMPC)Bay allele.

Associated phenotype
Zygosity
heterozygote
Testing protocol
Measured value
% Pre-pulse inhibition - PPI3
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6N
Phenotyping center
BCM

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

Statistical information

Batch effect significant true
Variance significant true
Genotype*Sex interaction effect p value 7.34x10-1
Genotype parameter estimate 1.300
Genotype standard error estimate 4.999
Genotype Effect P Value 7.34x10-1
Sex Parameter Estimate 1.300
Sex Standard Error Estimate 0.581
Sex Effect P Value 7.34x10-1
Intercept Estimate 74.603
Intercept Estimate Standard Error 0.432
Sex Male KO P Value 7.34x10-1
Sex Female KO P Value 7.34x10-1
WT Residuals Normality Tests 8.19x10-43
KO Residuals Normality Tests 5.83x10-1

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter