A Grip Strength phenotypic assay was performed on 1581 mice. The charts show the results of measuring Forelimb and hindlimb grip strength measurement mean in 8 female, 8 male mutants compared to 785 female, 780 male controls. The mutants are for the Bicd1tm1.1(KOMP)Wtsi allele.
decreased grip strength
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P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
| Forelimb and hindlimb grip strength measurement mean | UC Davis | Bicd1tm1.1(KOMP)Wtsi | homozygote | Early adult | TCPA0797Cre | 4.62x10-3 | 2.41x10-5 | 1.88x10-6 | |
Bicd1 data charts
Forelimb and hindlimb grip strength measurement meanExperiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Forelimb and hindlimb grip strength measurement mean
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NCrl
Phenotyping center
UC Davis
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Forelimb and hindlimb grip strength measurement mean / Box plot
Forelimb and hindlimb grip strength measurement mean / Scatter plot
Results of statistical analysis
Genotype P value
1.88x10-6
Genotype*Female P value
2.41x10-5
Genotype*Male P value
4.62x10-3
Classification
With phenotype threshold value 1e-04 - both sexes equally
Summary statistics of all data in the dataset
Statistical method
| Batch effect significant | true |
| Variance significant | true |
| Genotype*Sex interaction effect p value | 1.88x10-6 |
| Genotype parameter estimate | -5.663 |
| Genotype standard error estimate | 5.550 |
| Genotype Effect P Value | 1.88x10-6 |
| Sex Parameter Estimate | -5.663 |
| Sex Standard Error Estimate | 2.577 |
| Sex Effect P Value | 1.88x10-6 |
| Intercept Estimate | 161.945 |
| Intercept Estimate Standard Error | 8.697 |
| Sex Male KO P Value | 1.88x10-6 |
| Sex Female KO P Value | 1.88x10-6 |
| WT Residuals Normality Tests | 7.68x10-2 |
| KO Residuals Normality Tests | 5.85x10-1 |
Statistical analysis API access
Experimental data download
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