decreased prepulse inhibition

  Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
% Pre-pulse inhibition - PPI1UC DavisBicd1tm1.1(KOMP)WtsihomozygoteEarly adultTCPA0797Cre1.18x10-23.81x10-53.66x10-6

Bicd1 data charts

% Pre-pulse inhibition - PPI1
Combination tested with the lowest p-value of 3.66x10-6
Experiments performed

A Acoustic Startle and Pre-pulse Inhibition (PPI) phenotypic assay was performed on 1502 mice. The charts show the results of measuring % Pre-pulse inhibition - PPI1 in 8 female, 8 male mutants compared to 748 female, 738 male controls. The mutants are for the Bicd1tm1.1(KOMP)Wtsi allele.

Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
% Pre-pulse inhibition - PPI1
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NCrl
Phenotyping center
UC Davis

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

Statistical information

Batch effect significant false
Variance significant true
Genotype*Sex interaction effect p value 3.66x10-6
Genotype parameter estimate N/A
Genotype standard error estimate 5.176
Genotype Effect P Value 3.66x10-6
Sex Parameter Estimate N/A
Sex Standard Error Estimate N/A
Sex Effect P Value 3.66x10-6
Intercept Estimate -1.090
Intercept Estimate Standard Error 0.615
Sex Male KO P Value 3.66x10-6
Sex Female KO P Value 3.66x10-6
WT Residuals Normality Tests 2.09x10-15
KO Residuals Normality Tests 4.35x10-1

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