A Organ Weight phenotypic assay was performed on 712 mice. The charts show the results of measuring Spleen weight in female, 6 male mutants compared to 20 female, 686 male controls. The mutants are for the Nfil3tm1.1(KOMP)Vlcg allele.
increased spleen weight
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Spleen weight | UC Davis | Nfil3tm1.1(KOMP)Vlcg | homozygote | Early adult | BL5281 | 1.44x10-5 | — | — |
Nfil3 data charts
Spleen weightExperiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Spleen weight
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NCrl
Phenotyping center
UC Davis
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Spleen weight / Box plot
Spleen weight / Scatter plot
Results of statistical analysis
Genotype P value
1.44x10-5
Genotype*Female P value
N/A
Genotype*Male P value
N/A
Classification
With phenotype threshold value 1e-04 - a significant change for the one sex (male) tested
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | false |
Variance significant | true |
Genotype*Sex interaction effect p value | 1.44x10-5 |
Genotype parameter estimate | N/A |
Genotype standard error estimate | 0.005 |
Genotype Effect P Value | 1.44x10-5 |
Sex Parameter Estimate | N/A |
Sex Standard Error Estimate | N/A |
Sex Effect P Value | 1.44x10-5 |
Intercept Estimate | 0.043 |
Intercept Estimate Standard Error | 0.005 |
Sex Male KO P Value | 1.44x10-5 |
Sex Female KO P Value | 1.44x10-5 |
WT Residuals Normality Tests | 8.76x10-28 |
KO Residuals Normality Tests | 8.88x10-4 |
Statistical analysis API access
Experimental data download
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