increased circulating aspartate transaminase level

  Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Aspartate aminotransferaseUC DavisLumtm1.1(KOMP)VlcgheterozygoteEarly adultBL47353.15x10-18.2x10-87.42x10-8

Lum data charts

Aspartate aminotransferase
Combination tested with the lowest p-value of 7.42x10-8
Experiments performed

A Clinical Chemistry phenotypic assay was performed on 1477 mice. The charts show the results of measuring Aspartate aminotransferase in 8 female, 8 male mutants compared to 727 female, 734 male controls. The mutants are for the Lumtm1.1(KOMP)Vlcg allele.

Associated phenotype
Zygosity
heterozygote
Testing protocol
Measured value
Aspartate aminotransferase
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NCrl
Phenotyping center
UC Davis

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

Aspartate aminotransferase / Box plot
Aspartate aminotransferase / Scatter plot

Results of statistical analysis

Summary statistics of all data in the dataset

Statistical method

Batch effect significant true
Variance significant true
Genotype*Sex interaction effect p value 7.42x10-8
Genotype parameter estimate -10.106
Genotype standard error estimate 80.989
Genotype Effect P Value 7.42x10-8
Sex Parameter Estimate -10.106
Sex Standard Error Estimate 10.661
Sex Effect P Value 7.42x10-8
Intercept Estimate 223.324
Intercept Estimate Standard Error 10.977
Sex Male KO P Value 7.42x10-8
Sex Female KO P Value 7.42x10-8
WT Residuals Normality Tests 7.16x10-44
KO Residuals Normality Tests 1.92x10-1

Windowing parameters

View documentation about soft windowing
Sharpness (k) 5.426
Bandwidth (l)641

Experimental data download

Download data as:  

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