A Clinical Chemistry phenotypic assay was performed on 1477 mice. The charts show the results of measuring Aspartate aminotransferase in 8 female, 8 male mutants compared to 727 female, 734 male controls. The mutants are for the Lumtm1.1(KOMP)Vlcg allele.
increased circulating aspartate transaminase level
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Aspartate aminotransferase | UC Davis | Lumtm1.1(KOMP)Vlcg | heterozygote | Early adult | BL4735 | 3.15x10-1 | 8.2x10-8 | 7.42x10-8 |
Lum data charts
Aspartate aminotransferaseExperiments performed
Associated phenotype
Zygosity
heterozygote
Testing protocol
Measured value
Aspartate aminotransferase
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NCrl
Phenotyping center
UC Davis
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Aspartate aminotransferase / Box plot
Aspartate aminotransferase / Scatter plot
Results of statistical analysis
Genotype P value
7.42x10-8
Genotype*Female P value
8.2x10-8
Genotype*Male P value
3.15x10-1
Classification
Overally significant [level = 1e-04 , pvalue = 7.41994401476376e-08 ]; and with phenotype threshold value 1e-04 - females only
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 7.42x10-8 |
Genotype parameter estimate | -10.106 |
Genotype standard error estimate | 80.989 |
Genotype Effect P Value | 7.42x10-8 |
Sex Parameter Estimate | -10.106 |
Sex Standard Error Estimate | 10.661 |
Sex Effect P Value | 7.42x10-8 |
Intercept Estimate | 223.324 |
Intercept Estimate Standard Error | 10.977 |
Sex Male KO P Value | 7.42x10-8 |
Sex Female KO P Value | 7.42x10-8 |
WT Residuals Normality Tests | 7.16x10-44 |
KO Residuals Normality Tests | 1.92x10-1 |
Statistical analysis API access
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