decreased circulating cholesterol level

  Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Total cholesterolWTSIKif21btm1a(KOMP)WtsihomozygoteEarly adultEPD0076_1_F073.28x10-52.76x10-12.84x10-1

Kif21b data charts

Total cholesterol
Combination tested with the lowest p-value of 3.28x10-5
Experiments performed

A Clinical Chemistry phenotypic assay was performed on 1106 mice. The charts show the results of measuring Total cholesterol in 7 female, 6 male mutants compared to 542 female, 551 male controls. The mutants are for the Kif21btm1a(KOMP)Wtsi allele.

Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Total cholesterol
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6N
Phenotyping center
WTSI

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

Total cholesterol / Box plot
Total cholesterol / Scatter plot

Results of statistical analysis

Summary statistics of all data in the dataset

Statistical method

Batch effect significant true
Variance significant true
Genotype*Sex interaction effect p value 2.84x10-1
Genotype parameter estimate 1.180
Genotype standard error estimate 0.326
Genotype Effect P Value 2.84x10-1
Sex Parameter Estimate 1.180
Sex Standard Error Estimate 0.114
Sex Effect P Value 2.84x10-1
Intercept Estimate -0.386
Intercept Estimate Standard Error 0.433
Sex Male KO P Value 2.84x10-1
Sex Female KO P Value 2.84x10-1
WT Residuals Normality Tests 1.09x10-6
KO Residuals Normality Tests 4.56x10-1

Windowing parameters

View documentation about soft windowing
Sharpness (k) 8.324
Bandwidth (l)46

Experimental data download

Download data as:  

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