A Insulin Blood Level phenotypic assay was performed on 4677 mice. The charts show the results of measuring Insulin in 6 female, 7 male mutants compared to 2306 female, 2358 male controls. The mutants are for the Adcy9tm1b(EUCOMM)Wtsi allele.
increased circulating insulin level
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Insulin | WTSI | Adcy9tm1b(EUCOMM)Wtsi | heterozygote | Early adult | MUFE | 1.07x10-33 | 7.74x10-1 | 7.74x10-1 |
Adcy9 data charts
InsulinExperiments performed
Associated phenotype
Zygosity
heterozygote
Testing protocol
Measured value
Insulin
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6N
Phenotyping center
WTSI
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Insulin / Box plot
Insulin / Scatter plot
Results of statistical analysis
Genotype P value
7.74x10-1
Genotype*Female P value
7.74x10-1
Genotype*Male P value
1.07x10-33
Classification
Overally insignificant [level = 1e-04 , pvalue = 0.77353403124913 ]; but with phenotype threshold value 1e-04 - males only
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | false |
Variance significant | true |
Genotype*Sex interaction effect p value | 7.74x10-1 |
Genotype parameter estimate | -247.785 |
Genotype standard error estimate | 216.219 |
Genotype Effect P Value | 7.74x10-1 |
Sex Parameter Estimate | -247.785 |
Sex Standard Error Estimate | 31.078 |
Sex Effect P Value | 7.74x10-1 |
Intercept Estimate | -1433.909 |
Intercept Estimate Standard Error | 92.008 |
Sex Male KO P Value | 7.74x10-1 |
Sex Female KO P Value | 7.74x10-1 |
WT Residuals Normality Tests | 1.27x10-70 |
KO Residuals Normality Tests | 1.87x10-5 |
Statistical analysis API access
Experimental data download
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