increased circulating insulin level

  Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
InsulinWTSIAdcy9tm1b(EUCOMM)WtsiheterozygoteEarly adultMUFE1.07x10-337.74x10-17.74x10-1

Adcy9 data charts

Insulin
Combination tested with the lowest p-value of 1.07x10-33
Experiments performed

A Insulin Blood Level phenotypic assay was performed on 4677 mice. The charts show the results of measuring Insulin in 6 female, 7 male mutants compared to 2306 female, 2358 male controls. The mutants are for the Adcy9tm1b(EUCOMM)Wtsi allele.

Associated phenotype
Zygosity
heterozygote
Testing protocol
Measured value
Insulin
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6N
Phenotyping center
WTSI

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

Insulin / Box plot
Insulin / Scatter plot

Results of statistical analysis

Summary statistics of all data in the dataset

Statistical method

Batch effect significant false
Variance significant true
Genotype*Sex interaction effect p value 7.74x10-1
Genotype parameter estimate -247.785
Genotype standard error estimate 216.219
Genotype Effect P Value 7.74x10-1
Sex Parameter Estimate -247.785
Sex Standard Error Estimate 31.078
Sex Effect P Value 7.74x10-1
Intercept Estimate -1433.909
Intercept Estimate Standard Error 92.008
Sex Male KO P Value 7.74x10-1
Sex Female KO P Value 7.74x10-1
WT Residuals Normality Tests 1.27x10-70
KO Residuals Normality Tests 1.87x10-5

Windowing parameters

View documentation about soft windowing
Sharpness (k) 1.805
Bandwidth (l)721

Experimental data download

Download data as:  

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