A Clinical Chemistry phenotypic assay was performed on 1445 mice. The charts show the results of measuring Total cholesterol in 6 female, 7 male mutants compared to 713 female, 719 male controls. The mutants are for the Igfalstm1b(KOMP)Wtsi allele.
increased circulating cholesterol level
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Total cholesterol | UC Davis | Igfalstm1b(KOMP)Wtsi | homozygote | Early adult | TCPA0885Cre | 4.01x10-3 | 3.04x10-5 | 2.21x10-6 |
Igfals data charts
Total cholesterolExperiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Total cholesterol
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NCrl
Phenotyping center
UC Davis
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Total cholesterol / Box plot
Total cholesterol / Scatter plot
Results of statistical analysis
Genotype P value
2.21x10-6
Genotype*Female P value
3.04x10-5
Genotype*Male P value
4.01x10-3
Classification
With phenotype threshold value 1e-04 - both sexes equally
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 2.21x10-6 |
Genotype parameter estimate | 14.322 |
Genotype standard error estimate | 7.014 |
Genotype Effect P Value | 2.21x10-6 |
Sex Parameter Estimate | 14.322 |
Sex Standard Error Estimate | 2.354 |
Sex Effect P Value | 2.21x10-6 |
Intercept Estimate | 17.673 |
Intercept Estimate Standard Error | 6.992 |
Sex Male KO P Value | 2.21x10-6 |
Sex Female KO P Value | 2.21x10-6 |
WT Residuals Normality Tests | 7.51x10-12 |
KO Residuals Normality Tests | 6.18x10-2 |
Statistical analysis API access
Experimental data download
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