A Clinical Chemistry phenotypic assay was performed on 4404 mice. The charts show the results of measuring Alpha-amylase in 10 female, 13 male mutants compared to 2195 female, 2186 male controls. The mutants are for the Kcnj6em1(IMPC)H allele.
increased circulating amylase level
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Alpha-amylase | MRC Harwell | Kcnj6em1(IMPC)H | homozygote | Early adult | H-KCNJ6-DEL569-EM1-B6N | 2.42x10-3 | 8.18x10-6 | 1.7x10-5 |
Kcnj6 data charts
Alpha-amylaseExperiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Alpha-amylase
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NTac
Phenotyping center
MRC Harwell
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Alpha-amylase / Box plot
Alpha-amylase / Scatter plot
Results of statistical analysis
Genotype P value
1.7x10-5
Genotype*Female P value
8.18x10-6
Genotype*Male P value
2.42x10-3
Classification
Overally significant [level = 1e-04 , pvalue = 1.70151258490625e-05 ]; and with phenotype threshold value 1e-04 - different size as females greater
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 1.7x10-5 |
Genotype parameter estimate | 57.653 |
Genotype standard error estimate | 32.360 |
Genotype Effect P Value | 1.7x10-5 |
Sex Parameter Estimate | 57.653 |
Sex Standard Error Estimate | 10.046 |
Sex Effect P Value | 1.7x10-5 |
Intercept Estimate | 285.492 |
Intercept Estimate Standard Error | 28.718 |
Sex Male KO P Value | 1.7x10-5 |
Sex Female KO P Value | 1.7x10-5 |
WT Residuals Normality Tests | 1.4x10-14 |
KO Residuals Normality Tests | 1x10-3 |
Statistical analysis API access
Experimental data download
Download data as: