increased circulating amylase level

  Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Alpha-amylaseMRC HarwellKcnj6em1(IMPC)HhomozygoteEarly adultH-KCNJ6-DEL569-EM1-B6N2.42x10-38.18x10-61.7x10-5

Kcnj6 data charts

Alpha-amylase
Combination tested with the lowest p-value of 8.18x10-6
Experiments performed

A Clinical Chemistry phenotypic assay was performed on 4404 mice. The charts show the results of measuring Alpha-amylase in 10 female, 13 male mutants compared to 2195 female, 2186 male controls. The mutants are for the Kcnj6em1(IMPC)H allele.

Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Alpha-amylase
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NTac
Phenotyping center
MRC Harwell

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

Alpha-amylase / Box plot
Alpha-amylase / Scatter plot

Results of statistical analysis

Summary statistics of all data in the dataset

Statistical method

Batch effect significant true
Variance significant true
Genotype*Sex interaction effect p value 1.7x10-5
Genotype parameter estimate 57.653
Genotype standard error estimate 32.360
Genotype Effect P Value 1.7x10-5
Sex Parameter Estimate 57.653
Sex Standard Error Estimate 10.046
Sex Effect P Value 1.7x10-5
Intercept Estimate 285.492
Intercept Estimate Standard Error 28.718
Sex Male KO P Value 1.7x10-5
Sex Female KO P Value 1.7x10-5
WT Residuals Normality Tests 1.4x10-14
KO Residuals Normality Tests 1x10-3

Windowing parameters

View documentation about soft windowing
Sharpness (k) 8.324
Bandwidth (l)404

Experimental data download

Download data as:  

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