increased total body fat amount

  Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Fat/Body weightUC DavisTle4em1(IMPC)MbphomozygoteEarly adultCR15082.05x10-51.39x10-101.08x10-12
Fat massUC DavisTle4em1(IMPC)MbphomozygoteEarly adultCR15083.95x10-47.85x10-61.9x10-7

Tle4 data charts

Fat/Body weight
Combination tested with the lowest p-value of 1.08x10-12
Experiments performed

A Body Composition (DEXA lean/fat) phenotypic assay was performed on 972 mice. The charts show the results of measuring Fat/Body weight in 8 female, 6 male mutants compared to 470 female, 488 male controls. The mutants are for the Tle4em1(IMPC)Mbp allele.

Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Fat/Body weight
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NCrl
Phenotyping center
UC Davis

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

Fat/Body weight / Box plot
Fat/Body weight / Scatter plot

Results of statistical analysis

Summary statistics of all data in the dataset

Statistical method

Batch effect significant true
Variance significant true
Genotype*Sex interaction effect p value 1.08x10-12
Genotype parameter estimate 0.008
Genotype standard error estimate 0.016
Genotype Effect P Value 1.08x10-12
Sex Parameter Estimate 0.008
Sex Standard Error Estimate 0.004
Sex Effect P Value 1.08x10-12
Intercept Estimate 0.357
Intercept Estimate Standard Error 0.005
Sex Male KO P Value 1.08x10-12
Sex Female KO P Value 1.08x10-12
WT Residuals Normality Tests 6.26x10-1
KO Residuals Normality Tests 8.87x10-1

Windowing parameters

View documentation about soft windowing
Sharpness (k) 1.251
Bandwidth (l)812

Experimental data download

Download data as:  

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