decreased lean body mass

  Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Lean/Body weightUC DavisTle4em1(IMPC)MbphomozygoteEarly adultCR15082.2x10-51.72x10-101.59x10-12
Lean massUC DavisTle4em1(IMPC)MbphomozygoteEarly adultCR15088.29x10-47.05x10-63.53x10-7

Tle4 data charts

Lean/Body weight
Combination tested with the lowest p-value of 1.59x10-12
Experiments performed

A Body Composition (DEXA lean/fat) phenotypic assay was performed on 972 mice. The charts show the results of measuring Lean/Body weight in 8 female, 6 male mutants compared to 470 female, 488 male controls. The mutants are for the Tle4em1(IMPC)Mbp allele.

Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Lean/Body weight
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NCrl
Phenotyping center
UC Davis

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

Lean/Body weight / Box plot
Lean/Body weight / Scatter plot

Results of statistical analysis

Summary statistics of all data in the dataset

Statistical method

Batch effect significant true
Variance significant true
Genotype*Sex interaction effect p value 1.59x10-12
Genotype parameter estimate N/A
Genotype standard error estimate 0.016
Genotype Effect P Value 1.59x10-12
Sex Parameter Estimate N/A
Sex Standard Error Estimate N/A
Sex Effect P Value 1.59x10-12
Intercept Estimate 0.620
Intercept Estimate Standard Error 0.004
Sex Male KO P Value 1.59x10-12
Sex Female KO P Value 1.59x10-12
WT Residuals Normality Tests 7.88x10-1
KO Residuals Normality Tests 8.15x10-1

Windowing parameters

View documentation about soft windowing
Sharpness (k) 1.251
Bandwidth (l)812

Experimental data download

Download data as:  

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