A Body Composition (DEXA lean/fat) phenotypic assay was performed on 972 mice. The charts show the results of measuring Lean/Body weight in 8 female, 6 male mutants compared to 470 female, 488 male controls. The mutants are for the Tle4em1(IMPC)Mbp allele.
decreased lean body mass
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Lean/Body weight | UC Davis | Tle4em1(IMPC)Mbp | homozygote | Early adult | CR1508 | 2.2x10-5 | 1.72x10-10 | 1.59x10-12 | |
Lean mass | UC Davis | Tle4em1(IMPC)Mbp | homozygote | Early adult | CR1508 | 8.29x10-4 | 7.05x10-6 | 3.53x10-7 |
Tle4 data charts
Lean/Body weightExperiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Lean/Body weight
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NCrl
Phenotyping center
UC Davis
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Lean/Body weight / Box plot
Lean/Body weight / Scatter plot
Results of statistical analysis
Genotype P value
1.59x10-12
Genotype*Female P value
1.72x10-10
Genotype*Male P value
2.2x10-5
Classification
With phenotype threshold value 1e-04 - both sexes equally
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 1.59x10-12 |
Genotype parameter estimate | N/A |
Genotype standard error estimate | 0.016 |
Genotype Effect P Value | 1.59x10-12 |
Sex Parameter Estimate | N/A |
Sex Standard Error Estimate | N/A |
Sex Effect P Value | 1.59x10-12 |
Intercept Estimate | 0.620 |
Intercept Estimate Standard Error | 0.004 |
Sex Male KO P Value | 1.59x10-12 |
Sex Female KO P Value | 1.59x10-12 |
WT Residuals Normality Tests | 7.88x10-1 |
KO Residuals Normality Tests | 8.15x10-1 |
Statistical analysis API access
Experimental data download
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