A Organ Weight phenotypic assay was performed on 2783 mice. The charts show the results of measuring Heart weight in 8 female, 7 male mutants compared to 1377 female, 1391 male controls. The mutants are for the Tle4em1(IMPC)Mbp allele.
decreased heart weight
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
| Heart weight | UC Davis | Tle4em1(IMPC)Mbp | homozygote | Early adult | CR1508 | 2.23x10-3 | 3.35x10-3 | 3.15x10-5 | |
| Heart weight | UC Davis | Tle4em1(IMPC)Mbp | homozygote | Early adult | CR1508 | 2.23x10-3 | 3.35x10-3 | 3.15x10-5 | |
Tle4 data charts
Heart weightExperiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Heart weight
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NCrl
Phenotyping center
UC Davis
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Heart weight / Box plot
Heart weight / Scatter plot
Results of statistical analysis
Genotype P value
3.15x10-5
Genotype*Female P value
3.35x10-3
Genotype*Male P value
2.23x10-3
Classification
With phenotype threshold value 1e-04 - both sexes equally
Summary statistics of all data in the dataset
Statistical method
| Batch effect significant | true |
| Variance significant | true |
| Genotype*Sex interaction effect p value | 3.15x10-5 |
| Genotype parameter estimate | 0.012 |
| Genotype standard error estimate | 0.003 |
| Genotype Effect P Value | 3.15x10-5 |
| Sex Parameter Estimate | 0.012 |
| Sex Standard Error Estimate | 0.001 |
| Sex Effect P Value | 3.15x10-5 |
| Intercept Estimate | 0.052 |
| Intercept Estimate Standard Error | 0.002 |
| Sex Male KO P Value | 3.15x10-5 |
| Sex Female KO P Value | 3.15x10-5 |
| WT Residuals Normality Tests | 3.87x10-28 |
| KO Residuals Normality Tests | 7.65x10-1 |
Statistical analysis API access
Experimental data download
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