A Open Field phenotypic assay was performed on 2812 mice. The charts show the results of measuring Center distance travelled in 8 female, 8 male mutants compared to 1394 female, 1402 male controls. The mutants are for the Zbtb16em1(IMPC)Mbp allele.
hyperactivity
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Center distance travelled | UC Davis | Zbtb16em1(IMPC)Mbp | homozygote | Early adult | CR10728 | 2.53x10-2 | 5.51x10-10 | 5.51x10-10 | |
Number of center entries | UC Davis | Zbtb16em1(IMPC)Mbp | homozygote | Early adult | CR10728 | 4.38x10-2 | 2.58x10-7 | 2.58x10-7 | |
Distance travelled - total | UC Davis | Zbtb16em1(IMPC)Mbp | homozygote | Early adult | CR10728 | 2.38x10-1 | 2.85x10-7 | 4.19x10-7 | |
Whole arena average speed | UC Davis | Zbtb16em1(IMPC)Mbp | homozygote | Early adult | CR10728 | 2.49x10-1 | 3.17x10-7 | 4.38x10-7 | |
Center average speed | UC Davis | Zbtb16em1(IMPC)Mbp | homozygote | Early adult | CR10728 | 4.25x10-1 | 2.45x10-6 | 2.45x10-6 | |
Periphery average speed | UC Davis | Zbtb16em1(IMPC)Mbp | homozygote | Early adult | CR10728 | 1.48x10-1 | 1.37x10-5 | 1.37x10-5 |
Zbtb16 data charts
Center distance travelledExperiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Center distance travelled
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NCrl
Phenotyping center
UC Davis
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Center distance travelled / Box plot
Center distance travelled / Scatter plot
Results of statistical analysis
Genotype P value
5.51x10-10
Genotype*Female P value
5.51x10-10
Genotype*Male P value
2.53x10-2
Classification
Overally significant [level = 1e-04 , pvalue = 5.51189094366578e-10 ]; and with phenotype threshold value 1e-04 - different size as females greater
Summary statistics of all data in the dataset
Statistical method
Batch effect significant | true |
Variance significant | true |
Genotype*Sex interaction effect p value | 5.51x10-10 |
Genotype parameter estimate | 122.972 |
Genotype standard error estimate | 205.871 |
Genotype Effect P Value | 5.51x10-10 |
Sex Parameter Estimate | 122.972 |
Sex Standard Error Estimate | 35.593 |
Sex Effect P Value | 5.51x10-10 |
Intercept Estimate | 982.664 |
Intercept Estimate Standard Error | 102.837 |
Sex Male KO P Value | 5.51x10-10 |
Sex Female KO P Value | 5.51x10-10 |
WT Residuals Normality Tests | 8.18x10-32 |
KO Residuals Normality Tests | 1.55x10-1 |
Statistical analysis API access
Experimental data download
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