hyperactivity

  Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
Center distance travelledUC DavisZbtb16em1(IMPC)MbphomozygoteEarly adultCR107282.53x10-25.51x10-105.51x10-10
Number of center entriesUC DavisZbtb16em1(IMPC)MbphomozygoteEarly adultCR107284.38x10-22.58x10-72.58x10-7
Distance travelled - totalUC DavisZbtb16em1(IMPC)MbphomozygoteEarly adultCR107282.38x10-12.85x10-74.19x10-7
Whole arena average speedUC DavisZbtb16em1(IMPC)MbphomozygoteEarly adultCR107282.49x10-13.17x10-74.38x10-7
Center average speedUC DavisZbtb16em1(IMPC)MbphomozygoteEarly adultCR107284.25x10-12.45x10-62.45x10-6
Periphery average speedUC DavisZbtb16em1(IMPC)MbphomozygoteEarly adultCR107281.48x10-11.37x10-51.37x10-5

Zbtb16 data charts

Center distance travelled
Combination tested with the lowest p-value of 5.51x10-10
Experiments performed

A Open Field phenotypic assay was performed on 2812 mice. The charts show the results of measuring Center distance travelled in 8 female, 8 male mutants compared to 1394 female, 1402 male controls. The mutants are for the Zbtb16em1(IMPC)Mbp allele.

Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Center distance travelled
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NCrl
Phenotyping center
UC Davis

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

Center distance travelled / Box plot
Center distance travelled / Scatter plot

Results of statistical analysis

Summary statistics of all data in the dataset

Statistical method

Batch effect significant true
Variance significant true
Genotype*Sex interaction effect p value 5.51x10-10
Genotype parameter estimate 122.972
Genotype standard error estimate 205.871
Genotype Effect P Value 5.51x10-10
Sex Parameter Estimate 122.972
Sex Standard Error Estimate 35.593
Sex Effect P Value 5.51x10-10
Intercept Estimate 982.664
Intercept Estimate Standard Error 102.837
Sex Male KO P Value 5.51x10-10
Sex Female KO P Value 5.51x10-10
WT Residuals Normality Tests 8.18x10-32
KO Residuals Normality Tests 1.55x10-1

Windowing parameters

View documentation about soft windowing
Sharpness (k) 3.327
Bandwidth (l)1261

Experimental data download

Download data as:  

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