IMPC Release Notes

IMPC
  • Release: 4.2
  • Published: 08 December 2015
Statistical Package
  • PhenStat
  • Version: 2.2.0
Genome Assembly
  • Mus musculus
  • Version: GRCm38
Summary
  • Number of phenotyped genes: 2,432
  • Number of phenotyped mutant lines: 2,577
  • Number of phenotype calls: 13,008

Data access

Highlights

Data release 4.2

Data release 4.2 is a minor release to include more final QCed data and correct genetic background strain for some legacy lines.

Data Reports

Lines and Specimens

Phenotyping Center Mutant Lines Baseline Mice Mutant Mice
JAX 429 2,649 10,249
NING 93 985 1,362
TCP 254 3,885 10,582
HMGU 126 1,277 2,189
MRC Harwell 309 2,982 7,212
RBRC 32 968 696
ICS 104 1,038 1,655
WTSI 611 2,664 13,944
BCM 144 919 3,719
UC Davis 475 1,319 10,362

Experimental Data and Quality Checks

Data Type QC passed QC failed issues
categorical 6,431,595 756 * 4,776 *
unidimensional 4,797,248 7,553 * 113,998 *
time series 9,138,387 128 * 80,413 *
text 89,172 14,643 * 17,178 *
image record 208,924 0 0

* Excluded from statistical analysis.

Procedures

Allele Types

Mutation Name Mutant Lines
Targeted Mutation a 433
Targeted Mutation 1 733
Targeted Mutation b 1327
Targeted Mutation 2 5
Targeted Mutation c 2
Targeted Mutation d 1
Targeted Mutation e 44

Mouse knockout programs: KOMP,EUCOMM,NCOM,mirKO,IST12471H5

Distribution of Phenotype Annotations

Status

Overall

By Center

More charts and status information are available from iMits.

Phenotype Associations Overview

We provide a 'phenome' overview of statistically significant calls. By following the links below, you'll access the details of the phenotype calls for each center.

Phenotyping Center Significant MP Calls Pipeline
JAXBrowseIMPC_001
JAXBrowseJAX_001
NINGBrowseIMPC_001
TCPBrowseTCP_001
HMGUBrowseIMPC_001
HMGUBrowseHMGU_001
MRC HarwellBrowseHRWL_001
RBRCBrowseIMPC_001
ICSBrowseIMPC_001
ICSBrowseICS_001
WTSIBrowseMGP_001
BCMBrowseIMPC_001
BCMBrowseBCM_001
UC DavisBrowseUCD_001

Statistical Analysis

Statistical Methods

Data Statistical Method
categorical Fisher's exact test
unidimensional Wilcoxon rank sum test with continuity correction
unidimensional Mixed Model framework, generalized least squares, equation withoutWeight
unidimensional Mixed Model framework, linear mixed-effects model, equation withoutWeight

P-value distributions

Trends










Previous Releases