IMPC Release Notes

IMPC
  • Release: 3.3
  • Published: 25 August 2015
Statistical Package
  • PhenStat
  • Version: 2.2.0
Genome Assembly
  • Mus musculus
  • Version: GRCm38
Summary
  • Number of phenotyped genes: 1,466
  • Number of phenotyped mutant lines: 1,537
  • Number of phenotype calls: 6,278

Data access

Highlights

Data release 3.3

Data release 3.3 is a minor release to include more viability data.

Data Reports

Lines and Specimens

Phenotyping Center Mutant Lines Baseline Mice Mutant Mice
JAX 231 1,322 4,658
NING 13 142 196
TCP 165 571 2,903
HMGU 86 818 1,429
MRC Harwell 186 2,520 4,191
RBRC 13 523 244
ICS 65 675 1,007
WTSI 434 1,751 6,380
BCM 72 435 1,487
UC Davis 272 883 6,133

Experimental Data and Quality Checks

Data Type QC passed QC failed issues
categorical 3,956,543 0 3,426 *
unidimensional 2,981,261 3,726 * 39,065 *
time series 7,383,933 9 * 77,684 *
text 51,597 18,591 * 161 *
image record 107,044 0 0

* Excluded from statistical analysis.

Procedures

Allele Types

Mutation Name Mutant Lines
Targeted Mutation a 346
Targeted Mutation 1 431
Targeted Mutation b 779
Targeted Mutation 2 5
Targeted Mutation c 2
Targeted Mutation d 1
Targeted Mutation e 24

Mouse knockout programs: KOMP,EUCOMM,NCOM,mirKO,IST12471H5

Distribution of Phenotype Annotations

Status

Overall

By Center

More charts and status information are available from iMits.

Phenotype Associations Overview

We provide a 'phenome' overview of statistically significant calls. By following the links below, you'll access the details of the phenotype calls for each center.

Phenotyping Center Significant MP Calls Pipeline
JAXBrowseJAX_001
JAXBrowseIMPC_001
NINGBrowseIMPC_001
TCPBrowseTCP_001
HMGUBrowseHMGU_001
HMGUBrowseIMPC_001
MRC HarwellBrowseHRWL_001
MRC HarwellBrowseIMPC_001
RBRCBrowseIMPC_001
ICSBrowseICS_001
ICSBrowseIMPC_001
WTSIBrowseMGP_001
BCMBrowseBCM_001
BCMBrowseIMPC_001
UC DavisBrowseUCD_001

Statistical Analysis

Statistical Methods

Data Statistical Method
categorical Fisher's exact test
unidimensional Wilcoxon rank sum test with continuity correction
unidimensional Mixed Model framework, generalized least squares, equation withoutWeight
unidimensional Mixed Model framework, linear mixed-effects model, equation withoutWeight

P-value distributions

Trends










Previous Releases