IMPC Release Notes

IMPC
  • Release: 3.2
  • Published: 16 June 2015
Statistical Package
  • PhenStat
  • Version: 2.2.0
Genome Assembly
  • Mus musculus
  • Version: GRCm38
Summary
  • Number of phenotyped genes: 1,468
  • Number of phenotyped mutant lines: 1,540
  • Number of phenotype calls: 6,064

Data access

Highlights

Data release 3.2

Data release 3.2 is a minor release to include more 3I lines. This release brings the number of 3I datapoints to 1,118,939.

Data Reports

Lines and Specimens

Phenotyping Center Mutant Lines Baseline Mice Mutant Mice
MRC Harwell 186 2,520 4,191
RBRC 13 523 244
NING 13 142 196
HMGU 86 818 1,429
ICS 65 675 1,007
WTSI 434 1,751 6,380
JAX 232 1,322 4,675
UC Davis 273 883 6,138
TCP 166 571 2,917
BCM 72 435 1,487

Experimental Data and Quality Checks

Data Type QC passed QC failed issues
categorical 3,956,068 0 3,426 *
unidimensional 2,970,851 3,726 * 39,065 *
time series 7,415,471 9 * 77,684 *
text 51,611 18,591 * 161 *
image record 107,059 0 0

* Excluded from statistical analysis.

Procedures

Allele Types

Mutation Name Mutant Lines
Targeted Mutation 2 5
Targeted Mutation d 1
Targeted Mutation 1 420
Targeted Mutation e 25
Targeted Mutation b 779
Targeted Mutation c 2
Targeted Mutation a 359

Mouse knockout programs: KOMP,EUCOMM,NCOM,mirKO,IST12471H5

Distribution of Phenotype Annotations

Status

Overall

By Center

More charts and status information are available from iMits.

Phenotype Associations Overview

We provide a 'phenome' overview of statistically significant calls. By following the links below, you'll access the details of the phenotype calls for each center.

Phenotyping Center Significant MP Calls Pipeline
MRC HarwellBrowseIMPC_001
MRC HarwellBrowseHRWL_001
RBRCBrowseIMPC_001
NINGBrowseIMPC_001
HMGUBrowseIMPC_001
HMGUBrowseHMGU_001
ICSBrowseIMPC_001
ICSBrowseICS_001
WTSIBrowseMGP_001
JAXBrowseIMPC_001
JAXBrowseJAX_001
UC DavisBrowseUCD_001
TCPBrowseTCP_001
BCMBrowseIMPC_001

Statistical Analysis

Statistical Methods

Data Statistical Method
categorical Fisher's exact test
unidimensional Wilcoxon rank sum test with continuity correction
unidimensional Mixed Model framework, generalized least squares, equation withoutWeight
unidimensional Mixed Model framework, linear mixed-effects model, equation withoutWeight

P-value distributions

Trends










Previous Releases