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Previous IMPC Data Release 13.0 Notes

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IMPC

  • Release: 13.0
  • Published: 17-December-2020

Statistical Package

Genome Assembly

Summary

  • Number of phenotyped genes: 7,360
  • Number of phenotyped mutant lines: 7,970
  • Number of phenotype calls: 86,536

Data access

  • Ftp interface: ftp
  • RESTful interfaces: APIs

Highlights

Data release 13.0

Release notes:

Represents a major data release. This release

Data Reports

Total Number of Lines and Specimens in DR 13.0

Phenotyping Center Mutant Lines Baseline Mice Mutant Mice
TCP 661 8,151 27,160
JAX 1,710 11,841 46,344
HMGU 367 4,124 6,958
CCP-IMG 143 1,605 2,680
MRC Harwell 737 7,101 18,672
MARC 233 1,858 3,595
KMPC 57 1,478 1,936
RBRC 103 2,136 2,370
ICS 240 2,612 3,871
WTSI 1,600 5,372 18,660
UC Davis 1,406 7,376 32,485
BCM 714 6,229 20,880

Experimental Data and Quality Checks

Data Type QC Passed Data Points
categorical 20,780,695
image record 572,772
time series 18,293,301
ontological 1,240,938
text 415,798
unidimensional 15,584,538

* Excluded from statistical analysis.

Distribution of Phenotype Annotations

Created with Highcharts 9.1.0Number of genotype-phenotype associationsChart context menuDistribution of Phenotype Associations by Top-level MP Termhemizygoteheterozygotehomozygoteadipose tissue phenotypebehavior/neurological phenotypecardiovascular system phenotypecraniofacial phenotypedigestive/alimentary phenotypeembryo phenotypeendocrine/exocrine gland phenotypegrowth/size/body region phenotypehearing/vestibular/ear phenotypehematopoietic system phenotypehomeostasis/metabolism phenotypeimmune system phenotypeintegument phenotypelimbs/digits/tail phenotypeliver/biliary system phenotypemortality/agingmuscle phenotypenervous system phenotypepigmentation phenotyperenal/urinary system phenotypereproductive system phenotyperespiratory system phenotypeskeleton phenotypevision/eye phenotype01k2k3k4k5k6k7k8k9k

Production Status

Overall

Created with Highcharts 9.1.0Number of genesChart context menuGenotyping Status5 860​5 8603 521​3 52142​4231​31Genotype confirmedCre Excision CompleteChimeras obtainedMicro-injection in progress02k4k6k8k
Created with Highcharts 9.1.0Number of genesChart context menuPhenotyping StatusPhenotype attempt registeredPhenotyping startedPhenotyping data available

By Center

Created with Highcharts 9.1.0Number of GenesChart context menuGenotyping Status by CenterJAXTCPMonterotondoVETMEDUNIHarwellMonterotondo R&DSEATMARCOuluBCMCDTAHMGUCAM-SU GRCCCP-IMGCIPHECNBKMPCUCDICSWTSINARLabsRIKEN BRCMonashMicro-injection in progressChimeras obtainedGenotype confirmedCre Excision Complete01k2k3k4k5k6k7k
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Created with Highcharts 9.1.0Number of GenesChart context menuPhenotyping Status by CenterJAXTCPMonterotondoHarwellSEATMARCBCMCDTAHMGUCCP-IMGCIPHEKMPCUCDICSWTSIRIKEN BRCPhenotype Attempt RegisteredPhenotyping StartedPhenotyping Complete01k2k3k4k5k6k7k8k9k
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More charts and status information are available from our mouse tracking services iMits and GenTaR.

Phenotype Associations

Created with Highcharts 9.1.0Number of phenotype callsChart context menuNumber of Phenotype Calls by ProcedureFurther categorized by Embryo, Late Adult, and Early AdultEmbryoLate AdultEarly AdultGross Morphology Embryo E9.5Gross Morphology Placenta E9.5Viability E9.5 Secondary ScreenGross Morphology Embryo E12.5Gross Morphology Placenta E12.5Viability E12.5 Secondary ScreenGross Morphology Embryo E14.5-E15.5Gross Morphology Placenta E14.5-E15.5Viability E14.5-E15.5 Secondary ScreenGross Morphology Embryo E18.5Gross Morphology Placenta E18.5Viability E18.5 Secondary ScreenAcoustic Startle and Pre-pulse Inhibition (PPI)Auditory Brain Stem ResponseBody Composition (DEXA lean/fat)Body WeightChallenge Whole Body PlethysmographyClinical ChemistryCombined SHIRPA and DysmorphologyCortical Bone MicroCTEchoElectrocardiogram (ECG)Electroconvulsive Threshold TestingElectroretinographyEye MorphologyFear ConditioningFemoral MicroradiographyFertility of Homozygous Knock-out MiceGrip StrengthGross Pathology and Tissue CollectionHeart WeightHematologyHole-board ExplorationHot PlateImmunophenotypingIndirect CalorimetryInsulin Blood LevelIntraperitoneal glucose tolerance test (IPGTT)Light-Dark TestLung mechanics by forced oscillationsOpen FieldOpen Field - centre startOrgan WeightPlasma ChemistryRotarodSleep WakeTail SuspensionThree-point BendTrabecular Bone MicroCTUrinalysisVertebral MicroradiographyViability Primary ScreenX-ray01k2k3k4k5k6k7k
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Trends

Created with Highcharts 9.1.0Genes/Mutant LinesPhenotype CallsChart context menuGenes/Mutant Lines/MP CallsBy Data ReleasePhenotyped genesPhenotyped linesMP calls1.01.12.03.03.13.23.33.44.04.24.35.06.06.17.08.09.19.210.010.111.012.013.00250050007500100000300006000090000120000
Created with Highcharts 9.1.0Data PointsChart context menuData Points by Data ReleaseCategorical (QC passed)Image record (QC passed)ontological_datapoints_QC_passedText (QC passed)Time series (QC passed)Unidimensional (QC passed)1.01.12.03.03.13.23.33.44.04.24.35.06.06.17.08.09.19.210.010.111.012.013.00500000010000000150000002000000025000000
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