Phenotype: increased KLRG1-positive T-helper cell number

Definition
increase in the number of CD4-positive alpha-beta T-helper cells expressing KLRG1, a marker associated with activation
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with increased KLRG1-positive T-helper cell number

Total number of significant genotype-phenotype associations: 5

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Arpc1b
Arpc1btm1a(EUCOMM)Wtsi
HOM   Early adult increased KLRG1-positive T-helper cell number KLRG1+ CD4+ T helper cells - % of CD45+
Spleen Immunophenotyping
WTSI
3i
0.00
Cog6
Cog6tm1a(EUCOMM)Wtsi
HOM   Early adult increased KLRG1-positive T-helper cell number KLRG1+ CD4+ T helper cells - % of CD45+
Mesenteric Lymph Node Immunophenotyping
WTSI
3i
0.00
Dph6
Dph6tm1a(KOMP)Wtsi
HOM   Early adult increased KLRG1-positive T-helper cell number KLRG1+ CD4+ T helper cells - % of CD45+
Spleen Immunophenotyping
WTSI
3i
0.00
Sik3
Sik3tm1a(EUCOMM)Hmgu
HOM   Early adult increased KLRG1-positive T-helper cell number KLRG1+ CD4+ T helper cells - % of CD4+ T helper cells
Mesenteric Lymph Node Immunophenotyping
WTSI
3i
0.00
Zfp616
Zfp616tm1b(KOMP)Wtsi
HOM   Early adult increased KLRG1-positive T-helper cell number KLRG1+ CD4+ T helper cells - % of CD4+ T helper cells
Mesenteric Lymph Node Immunophenotyping
WTSI
3i
0.00

Download data as:   TSV   XLS

 The way we measure

 Phenotype associations stats

1.08% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased KLRG1-positive T-helper cell number (5/463)

0.00% females (0/6) 0.00% males (0/6)

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