Phenotype: increased effector memory T-helper cell number

Definition
increase in the number of CD4-positive alpha-beta T-helper cells with a CD44-positive, CD62L-negative memory phenotype
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with increased effector memory T-helper cell number

Total number of significant genotype-phenotype associations: 20

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value
Arpc1b
Arpc1btm1a(EUCOMM)Wtsi
HOM postnatal increased effector memory T-helper cell number Mesenteric Lymph Node Immunophenotyping | Effector CD4+ T helper cells - % of CD4+ T helper cells WTSI | 3i 0.00
Bach2
Bach2tm1a(EUCOMM)Wtsi
HOM postnatal increased effector memory T-helper cell number Mesenteric Lymph Node Immunophenotyping | Effector CD4+ T helper cells - % of CD4+ T helper cells WTSI | 3i 0.00
Cog6
Cog6tm1a(EUCOMM)Wtsi
HOM postnatal increased effector memory T-helper cell number Spleen Immunophenotyping | Effector CD4+ T helper cells - % of CD4+ T helper cells WTSI | 3i 0.00
Cxcr2
Cxcr2tm1a(EUCOMM)Wtsi
HOM postnatal increased effector memory T-helper cell number Spleen Immunophenotyping | Effector CD4+ T helper cells - % of CD4+ T helper cells WTSI | 3i 0.00
Dph6
Dph6tm1a(KOMP)Wtsi
HOM postnatal increased effector memory T-helper cell number Mesenteric Lymph Node Immunophenotyping | Effector CD4+ T helper cells - % of CD45+ WTSI | 3i 0.00
Gda
Gdatm1a(KOMP)Wtsi
HOM postnatal increased effector memory T-helper cell number Mesenteric Lymph Node Immunophenotyping | Resting CD4+ T helper cells - % of CD45+ WTSI | 3i 0.00
Nipsnap3a
Nipsnap3atm1b(KOMP)Wtsi
HOM postnatal increased effector memory T-helper cell number Mesenteric Lymph Node Immunophenotyping | Effector CD4+ T helper cells - % of CD45+ WTSI | 3i 0.00
Pepd
Pepdtm1a(KOMP)Wtsi
HOM postnatal increased effector memory T-helper cell number Mesenteric Lymph Node Immunophenotyping | Effector CD4+ T helper cells - % of CD45+ WTSI | 3i 0.00
Sik3
Sik3tm1a(EUCOMM)Hmgu
HOM postnatal increased effector memory T-helper cell number Mesenteric Lymph Node Immunophenotyping | Resting CD4+ T helper cells - % of CD45+ WTSI | 3i 0.00
Ydjc
Ydjctm1(KOMP)Wtsi
HOM postnatal increased effector memory T-helper cell number Spleen Immunophenotyping | Effector CD4+ T helper cells - % of CD45+ WTSI | 3i 0.00

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 The way we measure

 Phenotype associations stats

1.91% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased effector memory T-helper cell number (10/523)

1.91% females (10/523) 1.91% males (10/523)

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