MP:0013667 (increased immature NK cell number) | IMPC Phenotype Information | International Mouse Phenotyping Consortium

Phenotype: increased immature NK cell number

Definition

increase in the number of NK cells lacking expression of the maturation marker CD11b

Synonyms

increased immature natural killer cell number

of tested genes

significant genes

tested genes

Total number of significant genotype-phenotype associations: 4

Gene / Allele	Zygosity	Life Stage	Phenotype	Parameter	Phenotyping Center	P Value
Arpc1b Arpc1b^{tm1a(EUCOMM)Wtsi}	HOM	Early adult	increased immature NK cell number	Immature NK cells - % of NK cells Spleen Immunophenotyping	WTSI 3i	0.00
Gmds Gmds^{tm1a(KOMP)Wtsi}	HOM	Early adult	increased immature NK cell number	Immature NK cells - % of NK cells Spleen Immunophenotyping	WTSI 3i	0.00
Asb2 Asb2^{tm2b(KOMP)Wtsi}	HET	Early adult	increased Ly6C-positive immature NK cell number	NK Subsets (Q1) Immunophenotyping	KMPC IMPC	8.51×10^-26

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0.71% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased immature NK cell number (3/422)

1.43% females (1/70) 1.43% males (1/70)

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