Definition
anomaly in the number of dendritic cells expressing high levels of CD11b which usually depend on Irf4 for their development
0%
of tested genes
0
significant genes
0
tested genes
IMPC Gene variants with abnormal CD11b-high dendritic cell number
Total number of significant genotype-phenotype associations: 8
| Gene / Allele | Zygosity | Sex | Life Stage | Phenotype | Parameter | Phenotyping Center |
P Value |
|---|---|---|---|---|---|---|---|
| Bach2 Bach2tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased CD11b-high dendritic cell number | CD11b-high cDC - % of cDC Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Duoxa2 Duoxa2tm1b(KOMP)Wtsi |
HOM | Early adult | decreased CD11b-high dendritic cell number | CD11b-high cDC - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Pclaf Pclaftm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased CD11b-high dendritic cell number | CD11b-high cDC - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Trappc9 Trappc9tm1a(EUCOMM)Wtsi |
HOM | Early adult | increased CD11b-high dendritic cell number | CD11b-high cDC - % of cDC Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Nub1 Nub1tm1b(EUCOMM)Hmgu |
HOM | Early adult | decreased CD11b-high dendritic cell number | cDCs CD11b Type Immunophenotyping |
CCP-IMG IMPC |
1.39×10-06 | |
| Lgr5 Lgr5em1(IMPC)Kmpc |
HET | Early adult | increased CD11b-high dendritic cell number | cDCs CD11b Type Immunophenotyping |
KMPC IMPC |
7.90×10-06 | |
| Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
HOM | Early adult | increased CD11b-high dendritic cell number | cDCs CD11b Type Immunophenotyping |
ICS IMPC |
1.97×10-05 | |
| Bach2 Bach2tm1b(EUCOMM)Wtsi |
HOM | Early adult | decreased CD11b-high dendritic cell number | cDCs CD11b Type Immunophenotyping |
HMGU IMPC |
2.84×10-05 |