Genes Phenotypes

Phenotype: decreased cardiac stroke volume

Definition
reduction in the volume of blood pushed into the aorta with each beat of the heart
Significant gene associations The way we measure Phenotype stats
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with decreased cardiac stroke volume

Total number of significant genotype-phenotype associations: 21

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value
Ap4e1
Ap4e1tm1b(KOMP)Wtsi 		HOM Early adult decreased cardiac stroke volume Echo | Stroke Volume BCM | IMPC 7.09×10-09
Nek1
Nek1em1(IMPC)Bay 		HOM Early adult decreased cardiac stroke volume Echo | Stroke Volume BCM | IMPC 4.91×10-07
Nr1d1
Nr1d1tm1(KOMP)Vlcg 		HOM Early adult decreased cardiac stroke volume Echo | Stroke Volume BCM | IMPC 1.98×10-06
Golt1b
Golt1btm1b(EUCOMM)Wtsi 		HOM Early adult decreased cardiac stroke volume Echo | Stroke Volume HMGU | IMPC 4.99×10-06
Kcng2
Kcng2em1(IMPC)Bay 		HOM Early adult decreased cardiac stroke volume Echo | Stroke Volume BCM | IMPC 5.27×10-06
Map3k12
Map3k12tm1b(EUCOMM)Hmgu 		HET Early adult decreased cardiac stroke volume Echo | Stroke Volume BCM | IMPC 1.21×10-05
Fez2
Fez2em1(IMPC)Bay 		HOM Early adult decreased cardiac stroke volume Echo | Stroke Volume BCM | IMPC 1.87×10-05
A930017K11Rik
A930017K11Riktm1b(KOMP)Wtsi 		HOM Early adult decreased cardiac stroke volume Echo | Stroke Volume BCM | IMPC 2.05×10-05
Ube3c
Ube3ctm1b(EUCOMM)Hmgu 		HOM Early adult decreased cardiac stroke volume Echo | Stroke Volume HMGU | IMPC 2.09×10-05
Cdk5rap3
Cdk5rap3tm1b(EUCOMM)Hmgu 		HET Early adult decreased cardiac stroke volume Echo | Stroke Volume HMGU | IMPC 2.20×10-05
Sdc2
Sdc2tm1b(KOMP)Wtsi 		HOM Early adult decreased cardiac stroke volume Echo | Stroke Volume HMGU | IMPC 4.47×10-05
Kcns2
Kcns2em1(IMPC)Bay 		HOM Early adult decreased cardiac stroke volume Echo | Stroke Volume BCM | IMPC 6.31×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Echo

 Phenotype associations stats

0.97% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased cardiac stroke volume (12/1231)

0.00% females (0/1197) 1.29% males (12/930)



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