Definition
any structural anomaly of the arteries that carry oxygenated blood away from the heart to the body, as opposed to the pulmonary arteries, which carry deoxygenated blood to the lungs
Synonyms
systemic artery dysplasia,
systemic artery anomaly
0%
of tested genes
0
significant genes
0
tested genes
IMPC Gene variants with abnormal systemic artery morphology
Total number of significant genotype-phenotype associations: 9
| Gene / Allele | Zygosity | Sex | Life Stage | Phenotype | Parameter | Phenotyping Center |
P Value |
|---|---|---|---|---|---|---|---|
| Klrb1 Klrb1tm1b(EUCOMM)Wtsi |
HOM | Early adult | dilated aorta | Aortic diameter (Dao) Echo |
HMGU IMPC |
1.51×10-14 | |
| Lsm1 Lsm1tm1b(EUCOMM)Hmgu |
HET | Early adult | dilated aorta | Aortic diameter (Dao) Echo |
HMGU IMPC |
3.29×10-10 | |
| Asb7 Asb7em1(IMPC)Ccpcz |
HOM | Early adult | dilated aorta | Aortic diameter (Dao) Echo |
CCP-IMG IMPC |
3.57×10-06 | |
| Cpe Cpetm1b(EUCOMM)Hmgu |
HOM | Early adult | aorta stenosis | Aortic diameter (Dao) Echo |
HMGU IMPC |
6.12×10-06 | |
| Spart Sparttm2b(EUCOMM)Hmgu |
HOM | Early adult | dilated aorta | Aortic diameter (Dao) Echo |
HMGU IMPC |
1.36×10-05 | |
| Lsm1 Lsm1tm1b(EUCOMM)Hmgu |
HOM | Early adult | dilated aorta | Aortic diameter (Dao) Echo |
HMGU IMPC |
3.32×10-05 | |
| Sdc2 Sdc2tm1b(KOMP)Wtsi |
HOM | Early adult | aorta stenosis | Aortic diameter (Dao) Echo |
HMGU IMPC |
4.91×10-05 | |
| Dnajb11 Dnajb11tm1b(EUCOMM)Wtsi |
HET | Early adult | dilated aorta | Aortic diameter (Dao) Echo |
HMGU IMPC |
7.03×10-05 |