Phenotype: increased effector memory CD4-positive, alpha-beta T cell number

Definition
increased number of CD4-positive, alpha-beta memory T cells with the phenotype CCR7-negative, CD127-positive, CD45RO-positive, and CD25-negative
Synonyms
increased effector memory CD4-positive, alpha-beta T-cell number,  increased effector memory CD4-positive, alpha-beta T lymphocyte number,  increased effector memory CD4-positive, alpha-beta T-lymphocyte number,  increased effector CD4-positive, alpha-beta memory T lymphocyte number,  increased effector CD4-positive, alpha-beta memory T cell number,  increased effector CD4-positive, alpha-beta memory T-lymphocyte number,  increased effector CD4-positive, alpha-beta memory T-cell number
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with increased effector memory CD4-positive, alpha-beta T cell number

Total number of significant genotype-phenotype associations: 35

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value
Arhgap30
Arhgap30tm1a(EUCOMM)Wtsi
HOM postnatal increased effector memory CD4-positive, alpha-beta T cell number Whole blood peripheral blood leukocyte immunophenotyping | CD4+ CD44+ CD62L- alpha beta effector T cell percentage WTSI | 3i 0.00
Arhgef1
Arhgef1tm1a(EUCOMM)Wtsi
HOM postnatal increased effector memory CD4-positive, alpha-beta T cell number Whole blood peripheral blood leukocyte immunophenotyping | CD4+ CD44+ CD62L- alpha beta effector T cell number WTSI | 3i 0.00
Arpc1b
Arpc1btm1a(EUCOMM)Wtsi
HOM postnatal increased effector memory CD4-positive, alpha-beta T cell number Whole blood peripheral blood leukocyte immunophenotyping | CD4+ CD44+ CD62L- alpha beta effector T cell percentage WTSI | 3i 0.00
Atp11a
Atp11atm1a(KOMP)Wtsi
HET postnatal increased effector memory CD4-positive, alpha-beta T cell number Whole blood peripheral blood leukocyte immunophenotyping | CD4+ CD44+ CD62L- alpha beta effector T cell number WTSI | 3i 0.00
Bach2
Bach2tm1a(EUCOMM)Wtsi
HOM postnatal increased effector memory CD4-positive, alpha-beta T cell number Whole blood peripheral blood leukocyte immunophenotyping | CD4+ CD44+ CD62L- alpha beta effector T cell percentage WTSI | 3i 0.00
Cxcr2
Cxcr2tm1a(EUCOMM)Wtsi
HOM postnatal increased effector memory CD4-positive, alpha-beta T cell number Whole blood peripheral blood leukocyte immunophenotyping | CD4+ CD44+ CD62L- alpha beta effector T cell percentage WTSI | 3i 0.00
Dph6
Dph6tm1a(KOMP)Wtsi
HOM postnatal increased effector memory CD4-positive, alpha-beta T cell number Whole blood peripheral blood leukocyte immunophenotyping | CD4+ CD44+ CD62L- alpha beta effector T cell percentage WTSI | 3i 0.00
Hbs1l
Hbs1ltm1a(KOMP)Wtsi
HOM postnatal increased effector memory CD4-positive, alpha-beta T cell number Whole blood peripheral blood leukocyte immunophenotyping | CD4+ CD44+ CD62L- alpha beta effector T cell percentage WTSI | 3i 0.00
Pepd
Pepdtm1a(KOMP)Wtsi
HOM postnatal increased effector memory CD4-positive, alpha-beta T cell number Whole blood peripheral blood leukocyte immunophenotyping | CD4+ CD44+ CD62L- alpha beta effector T cell number WTSI | 3i 0.00
Spns2
Spns2tm1b(KOMP)Wtsi
HOM postnatal increased effector memory CD4-positive, alpha-beta T cell number Buffy coat peripheral blood leukocyte immunophenotyping | CD4+CD44+CD62L- percentage WTSI | 3i 2.55×10-40
Fbxo7
Fbxo7tm1a(EUCOMM)Wtsi
HOM postnatal increased effector memory CD4-positive, alpha-beta T cell number Buffy coat peripheral blood leukocyte immunophenotyping | CD4+CD44+CD62L- percentage WTSI | 3i 4.74×10-14
Arhgap25
Arhgap25tm1a(KOMP)Wtsi
HOM postnatal increased effector memory CD4-positive, alpha-beta T cell number Buffy coat peripheral blood leukocyte immunophenotyping | CD4+CD44+CD62L- percentage WTSI | 3i 1.56×10-07
Egfr
Egfrtm1a(EUCOMM)Wtsi
HET postnatal increased effector memory CD4-positive, alpha-beta T cell number Buffy coat peripheral blood leukocyte immunophenotyping | CD4+CD44+CD62L- percentage WTSI | 3i 4.43×10-07
Bap1
Bap1tm1a(EUCOMM)Hmgu
HET postnatal increased effector memory CD4-positive, alpha-beta T cell number Whole blood peripheral blood leukocyte immunophenotyping | CD4+ CD44+ CD62L- alpha beta effector T cell number WTSI | 3i 1.10×10-06
Supt7l
Supt7ltm1a(EUCOMM)Wtsi
HET postnatal increased effector memory CD4-positive, alpha-beta T cell number Buffy coat peripheral blood leukocyte immunophenotyping | CD4+CD44+CD62L- percentage WTSI | 3i 1.58×10-06
Tmod1
Tmod1tm1a(KOMP)Wtsi
HET postnatal increased effector memory CD4-positive, alpha-beta T cell number Buffy coat peripheral blood leukocyte immunophenotyping | CD4+CD44+CD62L- percentage WTSI | 3i 1.67×10-06
Spns2
Spns2tm1a(KOMP)Wtsi
HOM postnatal increased effector memory CD4-positive, alpha-beta T cell number Buffy coat peripheral blood leukocyte immunophenotyping | CD4+CD44+CD62L- percentage WTSI | 3i 2.53×10-06
Sytl1
Sytl1tm1a(KOMP)Wtsi
HOM postnatal increased effector memory CD4-positive, alpha-beta T cell number Buffy coat peripheral blood leukocyte immunophenotyping | CD4+CD44+CD62L- percentage WTSI | 3i 3.68×10-06
Zkscan14
Zkscan14tm1a(EUCOMM)Wtsi
HET postnatal increased effector memory CD4-positive, alpha-beta T cell number Buffy coat peripheral blood leukocyte immunophenotyping | CD4+CD44+CD62L- percentage WTSI | 3i 5.29×10-06
Xpnpep1
Xpnpep1tm1a(KOMP)Wtsi
HOM postnatal increased effector memory CD4-positive, alpha-beta T cell number Whole blood peripheral blood leukocyte immunophenotyping | CD4+ CD44+ CD62L- alpha beta effector T cell percentage WTSI | 3i 1.57×10-05
Enc1
Enc1tm1a(EUCOMM)Wtsi
HOM postnatal increased effector memory CD4-positive, alpha-beta T cell number Whole blood peripheral blood leukocyte immunophenotyping | CD4+ CD44+ CD62L- alpha beta effector T cell percentage WTSI | 3i 2.12×10-05
Etv3
Etv3em1(IMPC)Wtsi
HOM postnatal increased effector memory CD4-positive, alpha-beta T cell number Whole blood peripheral blood leukocyte immunophenotyping | CD4+ CD44+ CD62L- alpha beta effector T cell percentage WTSI | 3i 2.12×10-05
Mkrn2
Mkrn2tm1b(KOMP)Wtsi
HOM postnatal increased effector memory CD4-positive, alpha-beta T cell number Whole blood peripheral blood leukocyte immunophenotyping | CD4+ CD44+ CD62L- alpha beta effector T cell number WTSI | 3i 2.58×10-05
Hprt
HprtTg(CMV-Cre)Brd
HOM postnatal increased effector memory CD4-positive, alpha-beta T cell number Buffy coat peripheral blood leukocyte immunophenotyping | CD4+CD44+CD62L- percentage WTSI | 3i 4.24×10-05
Cog6
Cog6tm1a(EUCOMM)Wtsi
HOM postnatal increased effector memory CD4-positive, alpha-beta T cell number Whole blood peripheral blood leukocyte immunophenotyping | CD4+ CD44+ CD62L- alpha beta effector T cell percentage WTSI | 3i 5.41×10-05
Pex3
Pex3tm1a(EUCOMM)Wtsi
HOM postnatal increased effector memory CD4-positive, alpha-beta T cell number Buffy coat peripheral blood leukocyte immunophenotyping | CD4+CD44+CD62L- percentage WTSI | 3i 6.20×10-05
Arhgap18
Arhgap18tm1a(KOMP)Wtsi
HOM postnatal increased effector memory CD4-positive, alpha-beta T cell number Buffy coat peripheral blood leukocyte immunophenotyping | CD4+CD44+CD62L- percentage WTSI | 3i 8.52×10-05

Download data as:   TSV   XLS

 The way we measure

 Phenotype associations stats

1.96% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased effector memory CD4-positive, alpha-beta T cell number (26/1328)

0.85% females (11/1296) 0.62% males (8/1292)

Select a parameter    



The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter