MP:0005629 (abnormal lung weight) | IMPC Phenotype Information | International Mouse Phenotyping Consortium

Phenotype: abnormal lung weight

Definition

anomaly in the average weight of the lung

of tested genes

significant genes

tested genes

Total number of significant genotype-phenotype associations: 8

Gene / Allele	Zygosity	Life Stage	Phenotype	Parameter	Phenotyping Center	P Value
Siglec1 Siglec1^{tm1.1(KOMP)Vlcg}	HOM	Early adult	increased lung weight	Left lung weight Organ Weight	UC Davis IMPC	3.97×10^-07
Gh Gh^{tm1.1(KOMP)Vlcg}	HOM	Early adult	decreased lung weight	Right lung weight Organ Weight	UC Davis IMPC	2.92×10^-06
Ly86 Ly86^{tm1a(KOMP)Wtsi}	HET	Early adult	decreased lung weight	Right lung weight Organ Weight	UC Davis IMPC	3.68×10^-06
Hpcal4 Hpcal4^{tm1.1(KOMP)Vlcg}	HOM	Early adult	decreased lung weight	Left lung weight Organ Weight	UC Davis IMPC	8.25×10^-06
Apbb2 Apbb2^{tm1.1(KOMP)Vlcg}	HET	Early adult	increased lung weight	Left lung weight Organ Weight	UC Davis IMPC	1.71×10^-05
Thbd Thbd^{tm1.1(KOMP)Vlcg}	HET	Early adult	increased lung weight	Right lung weight Organ Weight	UC Davis IMPC	3.98×10^-05
Cldn18 Cldn18^{tm1.1(KOMP)Vlcg}	HOM	Early adult	increased lung weight	Left lung weight Organ Weight	UC Davis IMPC	6.34×10^-05
Kcnd1 Kcnd1^{tm1.1(KOMP)Vlcg}	HEM	Early adult	increased lung weight	Left lung weight Organ Weight	UC Davis IMPC	9.89×10^-05

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Procedure
Organ Weight

1.33% of tested genes with null mutations on a B6N genetic background have a phenotype association to abnormal lung weight (8/600)

0.00% females (0/19) 1.32% males (8/607)

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