Phenotype: abnormal lung weight

Definition
anomaly in the average weight of the lung
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with abnormal lung weight

Total number of significant genotype-phenotype associations: 7

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Siglec1
Siglec1tm1.1(KOMP)Vlcg
HOM   Early adult increased lung weight Left lung weight
Organ Weight
UC Davis
IMPC
3.97×10-07
Gh
Ghtm1.1(KOMP)Vlcg
HOM   Early adult decreased lung weight Right lung weight
Organ Weight
UC Davis
IMPC
2.92×10-06
Hpcal4
Hpcal4tm1.1(KOMP)Vlcg
HOM Early adult decreased lung weight Left lung weight
Organ Weight
UC Davis
IMPC
7.85×10-06
Thbd
Thbdtm1.1(KOMP)Vlcg
HET   Early adult increased lung weight Right lung weight
Organ Weight
UC Davis
IMPC
3.98×10-05
Cldn18
Cldn18tm1.1(KOMP)Vlcg
HOM   Early adult increased lung weight Right lung weight
Organ Weight
UC Davis
IMPC
4.45×10-05
Kcnd1
Kcnd1tm1.1(KOMP)Vlcg
HEM   Early adult increased lung weight Left lung weight
Organ Weight
UC Davis
IMPC
9.89×10-05

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 The way we measure

Procedure
Organ Weight

 Phenotype associations stats

0.96% of tested genes with null mutations on a B6N genetic background have a phenotype association to abnormal lung weight (6/624)

0.00% females (0/19) 0.34% males (2/592)

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