Phenotype: abnormal vertebral column morphology

Definition
any structural anomaly of the complete structure forming the rostral-caudal axis of the skeleton formed from the alternating segments of vertebra and intervertebral discs which support the spinal cord
Synonyms
abnormal backbone morphology,  abnormal spinal column morphology,  abnormal spine morphology
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with abnormal vertebral column morphology

Total number of significant genotype-phenotype associations: 234

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Duoxa2
Duoxa2tm1b(KOMP)Wtsi
HOM Early adult abnormal vertebral arch morphology Lumbar processes
X-ray
WTSI
IMPC
3.14×10-19
Mysm1
Mysm1tm1a(KOMP)Wtsi
HOM Early adult abnormal vertebrae morphology Shape of vertebrae
X-Ray
HMGU
EuroPhenome
5.48×10-17
Trabd2b
Trabd2bem2(IMPC)Ccpcz
HOM Early adult abnormal vertebrae morphology Shape of vertebrae
X-ray
CCP-IMG
IMPC
1.10×10-15
Pstpip2
Pstpip2em1(IMPC)Tcp
HOM Early adult abnormal vertebrae morphology Shape of vertebrae
X-ray
TCP
IMPC
4.09×10-14
Ppp5c
Ppp5ctm1a(EUCOMM)Wtsi
HOM Early adult increased lumbar vertebrae number Number of lumbar vertebrae
X-Ray
WTSI
EuroPhenome
1.31×10-12
Cyp27b1
Cyp27b1tm1b(EUCOMM)Hmgu
HOM Early adult abnormal vertebrae morphology Shape of vertebrae
X-ray
TCP
IMPC
2.24×10-12
Ttc28
Ttc28tm1b(EUCOMM)Hmgu
HOM Early adult vertebral fusion Fusion of vertebrae
X-ray
TCP
IMPC
2.24×10-12
Ttc28
Ttc28tm1b(EUCOMM)Hmgu
HOM Early adult abnormal vertebrae morphology Shape of vertebrae
X-ray
TCP
IMPC
2.24×10-12
Trabd2b
Trabd2bem2(IMPC)Ccpcz
HOM Early adult abnormal vertebral arch morphology Thoracic processes
X-ray
CCP-IMG
IMPC
1.27×10-11
Colec10
Colec10em2(IMPC)Tcp
HOM Early adult abnormal vertebrae morphology Shape of vertebrae
X-ray
TCP
IMPC
1.72×10-11
Sik3
Sik3tm1a(EUCOMM)Hmgu
HOM Early adult abnormal spine curvature Shape of spine
X-ray
WTSI
IMPC
2.50×10-11
Fbn2
Fbn2em1(IMPC)Rbrc
HOM Early adult abnormal vertebral arch morphology Lumbar processes
X-ray
RBRC
IMPC
6.97×10-11
Cbx5
Cbx5tm1a(EUCOMM)Wtsi
HOM Early adult vertebral transformation Transitional vertebrae
X-ray
WTSI
IMPC
1.56×10-10
Duoxa2
Duoxa2tm1b(KOMP)Wtsi
HOM Early adult abnormal vertebrae morphology Shape of vertebrae
X-ray
WTSI
IMPC
2.21×10-10
Sik3
Sik3tm1a(EUCOMM)Hmgu
HOM Early adult abnormal vertebrae morphology Shape of vertebrae
X-ray
WTSI
IMPC
2.21×10-10
Sik3
Sik3tm1a(EUCOMM)Hmgu
HOM Early adult kyphosis Kyphosis
X-ray
WTSI
IMPC
2.71×10-10
Asb16
Asb16em1(IMPC)Ccpcz
HOM Early adult increased caudal vertebrae number Number of caudal vertebrae
X-ray
CCP-IMG
IMPC
3.24×10-10
Cog6
Cog6tm1a(EUCOMM)Wtsi
HOM Early adult vertebral transformation Transitional vertebrae
X-ray
WTSI
IMPC
3.38×10-10
Slc29a1
Slc29a1tm2b(NCOM)Mfgc
HOM Early adult vertebral fusion Fusion of vertebrae
X-ray
TCP
IMPC
3.43×10-10
Ccnd2
Ccnd2tm1b(KOMP)Mbp
HOM Early adult abnormal spine curvature Shape of spine
X-ray
MRC Harwell
IMPC
7.84×10-10
Asb5
Asb5em1(IMPC)Ccpcz
HOM Early adult increased caudal vertebrae number Number of caudal vertebrae
X-ray
CCP-IMG
IMPC
1.08×10-09
Cbx5
Cbx5tm1a(EUCOMM)Wtsi
HOM Early adult vertebral fusion Fusion of vertebrae
X-ray
WTSI
IMPC
2.57×10-09
Mex3b
Mex3btm1b(KOMP)Wtsi
HOM Early adult vertebral transformation Transitional vertebrae
X-ray
CCP-IMG
IMPC
2.95×10-09
Dele1
Dele1em2(IMPC)Ccpcz
HOM Early adult increased caudal vertebrae number Number of caudal vertebrae
X-ray
CCP-IMG
IMPC
3.62×10-09
Trim9
Trim9em1(IMPC)Ccpcz
HOM Early adult abnormal vertebral arch morphology Cervical processes
X-ray
CCP-IMG
IMPC
3.72×10-09
Il2ra
Il2ratm1b(EUCOMM)Wtsi
HOM Early adult abnormal vertebrae morphology Shape of vertebrae
X-ray
ICS
IMPC
1.20×10-08
Mex3b
Mex3btm1b(KOMP)Wtsi
HOM Early adult abnormal vertebral arch morphology Lumbar processes
X-ray
CCP-IMG
IMPC
1.90×10-08
Uchl1
Uchl1tm1b(EUCOMM)Hmgu
HET Early adult abnormal spine curvature Shape of spine
X-ray
MRC Harwell
IMPC
2.27×10-08
Jmjd1c
Jmjd1ctm1a(EUCOMM)Wtsi
HET Early adult vertebral transformation Transitional vertebrae
X-ray
WTSI
IMPC
2.53×10-08
Tm9sf4
Tm9sf4tm1a(KOMP)Wtsi
HOM Early adult vertebral transformation Transitional vertebrae
X-ray
WTSI
IMPC
2.53×10-08
Mta1
Mta1tm1a(EUCOMM)Wtsi
HOM Early adult decreased lumbar vertebrae number Number of lumbar vertebrae
X-Ray
WTSI
EuroPhenome
3.61×10-08
Mta1
Mta1tm1a(EUCOMM)Wtsi
HET Early adult decreased caudal vertebrae number Number of caudal vertebrae
X-Ray
WTSI
EuroPhenome
3.66×10-08
Phex
Phexnot yet available
HOM Early adult abnormal vertebral arch morphology Processes on vertebrae
X-Ray
HMGU
EuroPhenome
4.04×10-08
Phex
Phexnot yet available
HOM Early adult abnormal vertebrae morphology Shape of vertebrae
X-Ray
HMGU
EuroPhenome
4.04×10-08
Cbx5
Cbx5tm1a(EUCOMM)Wtsi
HOM Early adult fusion of vertebral arches Fusion of processes
X-ray
WTSI
IMPC
4.88×10-08
Slc20a2
Slc20a2tm1a(EUCOMM)Wtsi
HOM Early adult kyphosis Kyphosis
X-ray
WTSI
IMPC
5.58×10-08
Aff3
Aff3tm1a(EUCOMM)Wtsi
HET Early adult abnormal vertebral arch morphology Thoracic processes
X-ray
WTSI
IMPC
5.92×10-08
Snx5
Snx5Snx5
HOM Early adult abnormal vertebrae morphology Shape of vertebrae
X-Ray
ICS
EuroPhenome
7.31×10-08
Asxl1
Asxl1tm1a(EUCOMM)Wtsi
HET Early adult increased lumbar vertebrae number Number of lumbar vertebrae
X-ray
WTSI
MGP
7.54×10-08
Krt27
Krt27em1(IMPC)Ccpcz
HOM Early adult lordosis Lordosis
X-ray
CCP-IMG
IMPC
8.67×10-08
Mysm1
Mysm1tm1a(KOMP)Wtsi
HOM Early adult decreased sacral vertebrae number Number of pelvic vertebrae
X-Ray
WTSI
EuroPhenome
8.95×10-08
4932438H23Rik
4932438H23Riktm1a(EUCOMM)Wtsi
HOM   Early adult abnormal vertebral arch morphology Thoracic processes
X-ray
WTSI
IMPC
1.02×10-07
Xbp1
Xbp1tm1a(EUCOMM)Wtsi
HET   Early adult abnormal vertebral arch morphology Thoracic processes
X-ray
WTSI
IMPC
1.02×10-07
Mex3b
Mex3btm1b(KOMP)Wtsi
HOM Early adult abnormal vertebrae morphology Shape of vertebrae
X-ray
CCP-IMG
IMPC
1.16×10-07
Fgf14
Fgf14em1(IMPC)Ccpcz
HOM   Early adult kyphosis Kyphosis
X-ray
CCP-IMG
IMPC
1.25×10-07
Asxl1
Asxl1tm1a(EUCOMM)Wtsi
HET Early adult decreased sacral vertebrae number Number of pelvic vertebrae
X-ray
WTSI
MGP
1.55×10-07
Dnase1l2
Dnase1l2tm1.1(KOMP)Wtsi
HOM Early adult fusion of vertebral arches Fusion of processes
X-ray
WTSI
IMPC
1.67×10-07
Wdr37
Wdr37tm1a(KOMP)Wtsi
HOM Early adult fusion of vertebral arches Fusion of processes
X-ray
WTSI
IMPC
1.67×10-07
Cenpj
Cenpjtm1a(EUCOMM)Wtsi
HOM Early adult abnormal vertebrae morphology Shape of vertebrae
X-ray
WTSI
MGP
1.89×10-07
Tram2
Tram2tm1a(KOMP)Wtsi
HOM   Early adult abnormal vertebral arch morphology Cervical processes
X-ray
WTSI
IMPC
2.10×10-07
Ube2g1
Ube2g1tm1b(EUCOMM)Hmgu
HOM   Early adult vertebral fusion Fusion of vertebrae
X-ray
RBRC
IMPC
2.60×10-07
Aff3
Aff3tm1a(EUCOMM)Wtsi
HOM Early adult abnormal vertebral arch morphology Thoracic processes
X-ray
WTSI
IMPC
3.07×10-07
Efna1
Efna1tm1a(EUCOMM)Wtsi
HOM Early adult increased lumbar vertebrae number Number of lumbar vertebrae
X-ray
WTSI
EuroPhenome
5.61×10-07
Il12a
Il12atm1b(EUCOMM)Hmgu
HOM Early adult vertebral fusion Fusion of vertebrae
X-ray
MRC Harwell
IMPC
5.70×10-07
Slc20a2
Slc20a2tm1a(EUCOMM)Wtsi
HOM Early adult abnormal spine curvature Shape of spine
X-ray
WTSI
IMPC
6.47×10-07
Setd3
Setd3tm1.1(NCOM)Mfgc
HOM   Early adult vertebral fusion Fusion of vertebrae
X-ray
TCP
IMPC
6.83×10-07
Rnf14
Rnf14em1(IMPC)Ccpcz
HOM   Early adult lordosis Lordosis
X-ray
CCP-IMG
IMPC
7.35×10-07
Ddi2
Ddi2tm1b(EUCOMM)Hmgu
HET   Early adult abnormal spine curvature Shape of spine
X-ray
CCP-IMG
IMPC
7.59×10-07
Gna11
Gna11tm1b(EUCOMM)Wtsi
HOM Early adult vertebral fusion Fusion of vertebrae
X-ray
MRC Harwell
IMPC
8.35×10-07
Sirt3
Sirt3tm1b(EUCOMM)Wtsi
HOM   Early adult vertebral fusion Fusion of vertebrae
X-ray
MRC Harwell
IMPC
8.39×10-07
Cul9
Cul9em1(IMPC)Ccpcz
HOM   Early adult abnormal vertebral arch morphology Thoracic processes
X-ray
CCP-IMG
IMPC
1.10×10-06
Zc3h8
Zc3h8em1(IMPC)Ccpcz
HET   Early adult lordosis Lordosis
X-ray
CCP-IMG
IMPC
1.25×10-06
Prss54
Prss54em1(IMPC)Ccpcz
HOM Early adult kyphosis Kyphosis
X-ray
CCP-IMG
IMPC
1.30×10-06
Selenon
Selenontm1a(KOMP)Wtsi
HOM   Early adult vertebral fusion Fusion of vertebrae
X-ray
WTSI
MGP
1.34×10-06
Dnase1l2
Dnase1l2tm1.1(KOMP)Wtsi
HOM Early adult vertebral fusion Fusion of vertebrae
X-ray
MRC Harwell
IMPC
1.42×10-06
Dnase1l2
Dnase1l2tm1.1(KOMP)Wtsi
HOM   Early adult abnormal vertebrae morphology Shape of vertebrae
X-ray
WTSI
MGP
1.51×10-06
Aff3
Aff3tm1a(EUCOMM)Wtsi
HOM Early adult vertebral transformation Transitional vertebrae
X-ray
WTSI
IMPC
1.79×10-06
Dph6
Dph6tm1a(KOMP)Wtsi
HOM Early adult vertebral transformation Transitional vertebrae
X-ray
WTSI
IMPC
1.79×10-06
L3mbtl2
L3mbtl2tm2a(EUCOMM)Wtsi
HET Early adult vertebral transformation Transitional vertebrae
X-ray
WTSI
IMPC
1.79×10-06
Ddi2
Ddi2tm1b(EUCOMM)Hmgu
HET Early adult decreased caudal vertebrae number Number of caudal vertebrae
X-ray
CCP-IMG
IMPC
1.91×10-06
Ankrd13a
Ankrd13aGt(RRH308)Byg
HOM   Early adult vertebral fusion Fusion of vertebrae
X-Ray
WTSI
MGP
1.94×10-06
Pdss2
Pdss2tm1b(EUCOMM)Hmgu
HET Early adult vertebral fusion Fusion of vertebrae
X-ray
MRC Harwell
IMPC
2.08×10-06
Prss54
Prss54em1(IMPC)Ccpcz
HOM Early adult abnormal spine curvature Shape of spine
X-ray
CCP-IMG
IMPC
2.51×10-06
Mysm1
Mysm1tm1a(KOMP)Wtsi
HOM   Early adult decreased caudal vertebrae number Number of caudal vertebrae
X-Ray
WTSI
EuroPhenome
2.77×10-06
Tram2
Tram2tm1a(KOMP)Wtsi
HOM Early adult kyphosis Kyphosis
X-ray
WTSI
IMPC
2.92×10-06
Dscc1
Dscc1tm1a(KOMP)Wtsi
HOM   Early adult vertebral fusion Fusion of vertebrae
X-ray
WTSI
MGP
2.95×10-06
1110059G10Rik
1110059G10Riktm1a(KOMP)Wtsi
HOM Early adult vertebral transformation Transitional vertebrae
X-ray
WTSI
IMPC
3.11×10-06
Mbd1
Mbd1em1(IMPC)Wtsi
HOM Early adult vertebral transformation Transitional vertebrae
X-ray
WTSI
IMPC
3.11×10-06
Barx2
Barx2tm1b(EUCOMM)Hmgu
HOM   Early adult abnormal vertebrae morphology Shape of vertebrae
X-ray
MRC Harwell
IMPC
3.16×10-06
Ccnd2
Ccnd2tm1b(KOMP)Mbp
HOM Late adult abnormal spine curvature Shape of spine
X-ray
MRC Harwell
IMPC
3.44×10-06
Ppp5c
Ppp5ctm1a(EUCOMM)Wtsi
HOM Early adult increased thoracic vertebrae number Number of thoracic vertebrae
X-Ray
WTSI
EuroPhenome
3.85×10-06
Cpt2
Cpt2tm1b(KOMP)Wtsi
HET Early adult abnormal vertebrae morphology Shape of vertebrae
X-ray
WTSI
IMPC
3.88×10-06
Spopl
Spopltm1a(EUCOMM)Wtsi
HOM Early adult abnormal vertebral arch morphology Thoracic processes
X-ray
WTSI
IMPC
4.03×10-06
Brd2
Brd2em1(IMPC)Wtsi
HET   Early adult abnormal vertebral arch morphology Cervical processes
X-ray
WTSI
IMPC
4.06×10-06
Supt5
Supt5tm2a(KOMP)Wtsi
HET Early adult vertebral transformation Transitional vertebrae
X-ray
WTSI
IMPC
4.61×10-06
Ezh2
Ezh2tm1a(EUCOMM)Wtsi
HET Early adult increased lumbar vertebrae number Number of lumbar vertebrae
X-ray
WTSI
MGP
4.90×10-06
Fbn2
Fbn2em1(IMPC)Rbrc
HOM   Early adult vertebral fusion Fusion of vertebrae
X-ray
RBRC
IMPC
5.16×10-06
Brdt
Brdttm1a(EUCOMM)Wtsi
HOM Early adult increased lumbar vertebrae number Number of lumbar vertebrae
X-ray
WTSI
EuroPhenome
5.18×10-06
Prdm8
Prdm8em1(IMPC)Wtsi
HOM   Early adult decreased caudal vertebrae number Number of caudal vertebrae
X-ray
CCP-IMG
IMPC
5.49×10-06
Dele1
Dele1em2(IMPC)Ccpcz
HOM   Early adult abnormal vertebral arch morphology Cervical processes
X-ray
CCP-IMG
IMPC
5.61×10-06
Ube2g1
Ube2g1tm1b(EUCOMM)Hmgu
HOM   Early adult fusion of vertebral arches Fusion of processes
X-ray
RBRC
IMPC
5.70×10-06
Mta1
Mta1tm1a(EUCOMM)Wtsi
HOM Early adult decreased sacral vertebrae number Number of pelvic vertebrae
X-Ray
WTSI
EuroPhenome
5.77×10-06
Abca4
Abca4tm1a(EUCOMM)Wtsi
HOM   Early adult enlarged caudal vertebrae Vertebral Height
Vertebral Microradiography
WTSI
IMPC
5.79×10-06
Tmem273
Tmem273em1(IMPC)Ccpcz
HOM Early adult vertebral transformation Transitional vertebrae
X-ray
CCP-IMG
IMPC
6.01×10-06
Setmar
Setmartm1a(EUCOMM)Wtsi
HOM Early adult abnormal vertebrae morphology Shape of vertebrae
X-ray
WTSI
EuroPhenome
6.42×10-06
Asxl1
Asxl1tm1a(EUCOMM)Wtsi
HET Early adult vertebral fusion Fusion of vertebrae
X-ray
WTSI
MGP
6.98×10-06
Ppp5c
Ppp5ctm1a(EUCOMM)Wtsi
HOM Early adult vertebral fusion Fusion of vertebrae
X-ray
WTSI
EuroPhenome
6.98×10-06
Ropn1l
Ropn1ltm1b(EUCOMM)Wtsi
HOM Early adult kyphosis Kyphosis
X-ray
WTSI
IMPC
7.53×10-06
Wdr37
Wdr37tm1a(KOMP)Wtsi
HOM Early adult kyphosis Kyphosis
X-ray
WTSI
IMPC
7.53×10-06
Aff3
Aff3tm1a(EUCOMM)Wtsi
HOM Early adult fusion of vertebral arches Fusion of processes
X-ray
WTSI
IMPC
7.64×10-06
Mta1
Mta1tm1a(EUCOMM)Wtsi
HOM Early adult decreased caudal vertebrae number Number of caudal vertebrae
X-Ray
WTSI
EuroPhenome
8.65×10-06
Cul9
Cul9em1(IMPC)Ccpcz
HOM   Early adult vertebral transformation Transitional vertebrae
X-ray
CCP-IMG
IMPC
9.13×10-06
Hcar1
Hcar1em1(IMPC)Ccpcz
HOM   Early adult vertebral transformation Transitional vertebrae
X-ray
CCP-IMG
IMPC
9.13×10-06
Mta1
Mta1tm1a(EUCOMM)Wtsi
HET   Early adult decreased lumbar vertebrae number Number of lumbar vertebrae
X-Ray
WTSI
EuroPhenome
9.14×10-06
Mta1
Mta1tm1a(EUCOMM)Wtsi
HET   Early adult decreased sacral vertebrae number Number of pelvic vertebrae
X-Ray
WTSI
EuroPhenome
9.14×10-06
Slc25a4
Slc25a4tm1a(EUCOMM)Wtsi
HOM   Early adult fusion of vertebral arches Fusion of processes
X-ray
WTSI
IMPC
9.17×10-06
Xndc1
Xndc1tm1a(EUCOMM)Wtsi
HOM   Early adult fusion of vertebral arches Fusion of processes
X-ray
WTSI
IMPC
9.17×10-06
Mir129-2
Mir129-2em1(IMPC)KMPC
HOM Late adult abnormal spine curvature Shape of spine
X-ray
KMPC
IMPC
1.03×10-05
Tram2
Tram2tm1a(KOMP)Wtsi
HOM Early adult abnormal spine curvature Shape of spine
X-ray
WTSI
IMPC
1.08×10-05
Arpc1b
Arpc1btm1a(EUCOMM)Wtsi
HOM Early adult vertebral fusion Fusion of vertebrae
X-ray
WTSI
IMPC
1.10×10-05
Fggy
Fggytm1a(KOMP)Wtsi
HOM   Early adult vertebral fusion Fusion of vertebrae
X-ray
WTSI
IMPC
1.15×10-05
Gm13547
Gm13547tm1a(KOMP)Wtsi
HOM   Early adult vertebral fusion Fusion of vertebrae
X-ray
WTSI
IMPC
1.15×10-05
Zscan2
Zscan2tm1a(KOMP)Wtsi
HOM   Early adult vertebral fusion Fusion of vertebrae
X-ray
WTSI
IMPC
1.15×10-05
Btbd3
Btbd3tm1b(EUCOMM)Hmgu
HOM   Early adult abnormal vertebral arch morphology Thoracic processes
X-ray
CCP-IMG
IMPC
1.19×10-05
Fgf14
Fgf14em1(IMPC)Ccpcz
HOM Early adult decreased caudal vertebrae number Number of caudal vertebrae
X-ray
CCP-IMG
IMPC
1.20×10-05
Gyg
Gygtm1b(KOMP)Wtsi
HET Early adult vertebral fusion Fusion of vertebrae
X-ray
BCM
IMPC
1.25×10-05
Rnf148
Rnf148em1(IMPC)Ccpcz
HOM Early adult abnormal spine curvature Shape of spine
X-ray
CCP-IMG
IMPC
1.26×10-05
Rnf168
Rnf168tm2b(EUCOMM)Hmgu
HOM   Early adult kyphosis Kyphosis
X-ray
CCP-IMG
IMPC
1.28×10-05
Abca4
Abca4tm1a(EUCOMM)Wtsi
HOM Early adult vertebral fusion Fusion of vertebrae
X-ray
WTSI
IMPC
1.31×10-05
Ushbp1
Ushbp1tm1a(EUCOMM)Wtsi
HOM Early adult vertebral fusion Fusion of vertebrae
X-ray
WTSI
IMPC
1.31×10-05
Prkab1
Prkab1tm1b(KOMP)Wtsi
HOM   Early adult decreased caudal vertebrae number Number of caudal vertebrae
X-ray
CCP-IMG
IMPC
1.34×10-05
Mysm1
Mysm1tm1a(KOMP)Wtsi
HET Early adult abnormal vertebral arch morphology Processes on vertebrae
X-Ray
WTSI
EuroPhenome
1.42×10-05
Rnf168
Rnf168tm2b(EUCOMM)Hmgu
HOM   Early adult abnormal spine curvature Shape of spine
X-ray
CCP-IMG
IMPC
1.50×10-05
Tpte
Tpteem1(IMPC)KMPC
HOM Early adult kyphosis Kyphosis
X-ray
KMPC
IMPC
1.51×10-05
Tpte
Tpteem1(IMPC)KMPC
HOM Early adult abnormal spine curvature Shape of spine
X-ray
KMPC
IMPC
1.51×10-05
Nisch
Nischtm1b(EUCOMM)Hmgu
HOM Early adult abnormal spine curvature Shape of spine
X-ray
MRC Harwell
IMPC
1.54×10-05
Plekhm1
Plekhm1tm1b(EUCOMM)Hmgu
HOM Early adult abnormal vertebrae morphology Shape of vertebrae
X-ray
TCP
IMPC
1.58×10-05
Rnf148
Rnf148em1(IMPC)Ccpcz
HOM Early adult kyphosis Kyphosis
X-ray
CCP-IMG
IMPC
1.60×10-05
Skida1
Skida1tm1(KOMP)Wtsi
HET Early adult abnormal vertebral arch morphology Thoracic processes
X-ray
WTSI
IMPC
1.62×10-05
Slc25a30
Slc25a30tm1a(EUCOMM)Wtsi
HOM Early adult abnormal vertebral arch morphology Thoracic processes
X-ray
WTSI
IMPC
1.62×10-05
Pld5
Pld5tm1b(KOMP)Wtsi
HOM Early adult abnormal vertebral arch morphology Thoracic processes
X-ray
WTSI
IMPC
1.74×10-05
Kcnv2
Kcnv2tm1Wtsi
HOM Early adult kyphosis Kyphosis
X-ray
WTSI
IMPC
1.79×10-05
Gbx1
Gbx1Gbx1
HOM Early adult vertebral fusion Fusion of vertebrae
X-Ray
ICS
EuroPhenome
1.80×10-05
Mbd1
Mbd1em1(IMPC)Wtsi
HOM Early adult lordosis Lordosis
X-ray
WTSI
IMPC
1.90×10-05
Dbn1
Dbn1tm1b(KOMP)Wtsi
HET Early adult abnormal vertebrae morphology Shape of vertebrae
X-ray
MRC Harwell
IMPC
2.01×10-05
Fgf14
Fgf14em1(IMPC)Ccpcz
HOM Early adult abnormal spine curvature Shape of spine
X-ray
CCP-IMG
IMPC
2.07×10-05
Ap4e1
Ap4e1tm1b(KOMP)Wtsi
HOM Early adult abnormal vertebral arch morphology Lumbar processes
X-ray
CCP-IMG
IMPC
2.19×10-05
Arpc2
Arpc2tm1a(EUCOMM)Wtsi
HET   Early adult vertebral fusion Fusion of vertebrae
X-ray
WTSI
MGP
2.22×10-05
Kat14
Kat14tm1a(KOMP)Wtsi
HOM   Early adult vertebral fusion Fusion of vertebrae
X-ray
WTSI
EuroPhenome
2.22×10-05
Gldc
Gldctm1a(EUCOMM)Wtsi
HET   Early adult abnormal vertebral arch morphology Thoracic processes
X-ray
WTSI
IMPC
2.29×10-05
Ralb
Ralbtm1a(EUCOMM)Wtsi
HOM   Early adult abnormal vertebral arch morphology Thoracic processes
X-ray
WTSI
IMPC
2.29×10-05
Sh2d5
Sh2d5tm1a(EUCOMM)Wtsi
HOM   Early adult abnormal vertebral arch morphology Thoracic processes
X-ray
WTSI
IMPC
2.29×10-05
Vps53
Vps53tm1a(KOMP)Wtsi
HET   Early adult abnormal vertebral arch morphology Thoracic processes
X-ray
WTSI
IMPC
2.29×10-05
Rhou
Rhoutm1a(KOMP)Wtsi
HOM   Early adult vertebral fusion Fusion of vertebrae
X-ray
WTSI
MGP
2.29×10-05
Rnf168
Rnf168tm2b(EUCOMM)Hmgu
HOM   Early adult vertebral fusion Fusion of vertebrae
X-ray
CCP-IMG
IMPC
3.05×10-05
Btbd3
Btbd3tm1b(EUCOMM)Hmgu
HOM Early adult abnormal vertebrae morphology Shape of vertebrae
X-ray
CCP-IMG
IMPC
3.17×10-05
Cul9
Cul9em1(IMPC)Ccpcz
HOM Early adult abnormal vertebrae morphology Shape of vertebrae
X-ray
CCP-IMG
IMPC
3.17×10-05
Dscc1
Dscc1tm1a(KOMP)Wtsi
HOM Early adult increased lumbar vertebrae number Number of lumbar vertebrae
X-ray
WTSI
MGP
3.19×10-05
Klf7
Klf7tm1b(EUCOMM)Hmgu
HET Early adult abnormal vertebrae morphology Shape of vertebrae
X-ray
MRC Harwell
IMPC
3.34×10-05
Lrrk1
Lrrk1tm1b(KOMP)Wtsi
HOM Early adult abnormal vertebrae morphology Shape of vertebrae
X-ray
MRC Harwell
IMPC
3.34×10-05
Notch1
Notch1tm1b(EUCOMM)Hmgu
HET Early adult abnormal vertebrae morphology Shape of vertebrae
X-ray
MRC Harwell
IMPC
3.34×10-05
Rlim
Rlimem1(IMPC)Rbrc
HEM Early adult fusion of vertebral arches Fusion of processes
X-ray
RBRC
IMPC
3.41×10-05
Mysm1
Mysm1tm1a(KOMP)Wtsi
HOM Early adult vertebral fusion Fusion of vertebrae
X-Ray
WTSI
EuroPhenome
3.65×10-05
Arpc1b
Arpc1btm1a(EUCOMM)Wtsi
HOM Early adult fusion of vertebral arches Fusion of processes
X-ray
WTSI
IMPC
3.70×10-05
Cenpj
Cenpjtm1a(EUCOMM)Wtsi
HOM Early adult vertebral fusion Fusion of vertebrae
X-ray
WTSI
MGP
3.72×10-05
Lyplal1
Lyplal1tm1a(KOMP)Wtsi
HOM Early adult vertebral fusion Fusion of vertebrae
X-ray
WTSI
IMPC
3.92×10-05
Os9
Os9tm1a(EUCOMM)Wtsi
HOM Early adult vertebral fusion Fusion of vertebrae
X-ray
WTSI
IMPC
3.92×10-05
Sel1l
Sel1ltm1e(KOMP)Wtsi
HET Early adult vertebral fusion Fusion of vertebrae
X-ray
WTSI
IMPC
3.92×10-05
Setd5
Setd5tm1a(EUCOMM)Wtsi
HET Early adult vertebral fusion Fusion of vertebrae
X-ray
WTSI
IMPC
3.92×10-05
Wdr37
Wdr37tm1a(KOMP)Wtsi
HOM Early adult vertebral fusion Fusion of vertebrae
X-ray
WTSI
IMPC
3.92×10-05
Pex3
Pex3tm1a(EUCOMM)Wtsi
HOM   Early adult abnormal vertebrae morphology Shape of vertebrae
X-ray
WTSI
MGP
4.16×10-05
Mpp6
Mpp6em1(IMPC)Rbrc
HOM   Early adult fusion of vertebral arches Fusion of processes
X-ray
RBRC
IMPC
4.45×10-05
Epc2
Epc2tm1e(EUCOMM)Wtsi
HET Early adult abnormal vertebral arch morphology Processes on vertebrae
X-Ray
WTSI
EuroPhenome
4.47×10-05
Klk13
Klk13em1(IMPC)Ccpcz
HOM Early adult decreased caudal vertebrae number Number of caudal vertebrae
X-ray
CCP-IMG
IMPC
4.53×10-05
Dbn1
Dbn1tm1b(KOMP)Wtsi
HET Early adult decreased caudal vertebrae number Number of caudal vertebrae
X-ray
CCP-IMG
IMPC
4.56×10-05
Coa6
Coa6em1(IMPC)Ccpcz
HET   Early adult abnormal vertebral arch morphology Processes on vertebrae
X-ray
CCP-IMG
IMPC
4.86×10-05
Dcbld2
Dcbld2tm1a(KOMP)Wtsi
HOM   Early adult abnormal vertebral arch morphology Cervical processes
X-ray
WTSI
IMPC
4.87×10-05
Glg1
Glg1tm1a(KOMP)Wtsi
HET   Early adult abnormal vertebral arch morphology Cervical processes
X-ray
WTSI
IMPC
4.87×10-05
Kera
Keraem1(IMPC)Wtsi
HOM   Early adult abnormal vertebral arch morphology Cervical processes
X-ray
WTSI
IMPC
4.87×10-05
Selenok
Selenoktm1b(EUCOMM)Wtsi
HOM   Early adult abnormal vertebral arch morphology Cervical processes
X-ray
WTSI
IMPC
4.87×10-05
Wdtc1
Wdtc1tm1a(KOMP)Wtsi
HOM   Early adult abnormal vertebral arch morphology Cervical processes
X-ray
WTSI
IMPC
4.87×10-05
Mtch2
Mtch2tm1b(EUCOMM)Hmgu
HET Early adult abnormal vertebrae morphology Shape of vertebrae
X-ray
MRC Harwell
IMPC
5.00×10-05
Tmc6
Tmc6tm1a(EUCOMM)Wtsi
HOM   Early adult vertebral fusion Fusion of vertebrae
X-ray
WTSI
IMPC
5.02×10-05
Dnase1l2
Dnase1l2tm1.1(KOMP)Wtsi
HOM Early adult abnormal spine curvature Shape of spine
X-ray
WTSI
IMPC
5.04×10-05
H2-Eb1
H2-Eb1tm1a(KOMP)Wtsi
HOM Early adult abnormal spine curvature Shape of spine
X-ray
WTSI
IMPC
5.04×10-05
Pabpc4
Pabpc4tm1a(KOMP)Wtsi
HOM Early adult abnormal spine curvature Shape of spine
X-ray
WTSI
IMPC
5.04×10-05
Ropn1l
Ropn1ltm1b(EUCOMM)Wtsi
HOM Early adult abnormal spine curvature Shape of spine
X-ray
WTSI
IMPC
5.04×10-05
Selenok
Selenoktm1b(EUCOMM)Wtsi
HOM Early adult abnormal spine curvature Shape of spine
X-ray
WTSI
IMPC
5.04×10-05
Wdr37
Wdr37tm1a(KOMP)Wtsi
HOM Early adult abnormal spine curvature Shape of spine
X-ray
WTSI
IMPC
5.04×10-05
Mir129-2
Mir129-2em1(IMPC)KMPC
HOM Late adult abnormal vertebral arch morphology Processes on vertebrae
X-ray
KMPC
IMPC
5.05×10-05
Slc25a21
Slc25a21tm1a(KOMP)Wtsi
HOM   Early adult vertebral fusion Fusion of vertebrae
X-ray
WTSI
MGP
5.49×10-05
Fbxo25
Fbxo25em1(IMPC)Ccpcz
HOM Early adult abnormal vertebral arch morphology Thoracic processes
X-ray
CCP-IMG
IMPC
5.77×10-05
Cluh
Cluhem1(IMPC)Ccpcz
HET   Early adult abnormal vertebral arch morphology Cervical processes
X-ray
CCP-IMG
IMPC
6.49×10-05
Cnpy2
Cnpy2em1(IMPC)Wtsi
HOM Early adult abnormal vertebrae morphology Shape of vertebrae
X-ray
CCP-IMG
IMPC
6.84×10-05
Asb5
Asb5em1(IMPC)Ccpcz
HOM   Early adult abnormal vertebrae morphology Shape of vertebrae
X-ray
CCP-IMG
IMPC
7.17×10-05
Hbs1l
Hbs1ltm1a(KOMP)Wtsi
HOM Early adult vertebral transformation Transitional vertebrae
X-ray
WTSI
IMPC
7.17×10-05
Kdm7a
Kdm7atm1a(EUCOMM)Wtsi
HOM Early adult vertebral transformation Transitional vertebrae
X-ray
WTSI
IMPC
7.17×10-05
Mau2
Mau2tm1b(KOMP)Wtsi
HET Early adult vertebral transformation Transitional vertebrae
X-ray
WTSI
IMPC
7.17×10-05
Pitx1
Pitx1em1(IMPC)Wtsi
HET Early adult vertebral transformation Transitional vertebrae
X-ray
WTSI
IMPC
7.17×10-05
Scaf11
Scaf11em1(IMPC)Wtsi
HOM Early adult vertebral transformation Transitional vertebrae
X-ray
WTSI
IMPC
7.17×10-05
Ap4e1
Ap4e1tm1b(KOMP)Wtsi
HOM Early adult abnormal vertebrae morphology Shape of vertebrae
X-ray
CCP-IMG
IMPC
7.59×10-05
Tmem273
Tmem273em1(IMPC)Ccpcz
HOM Early adult abnormal vertebrae morphology Shape of vertebrae
X-ray
CCP-IMG
IMPC
7.59×10-05
Dcdc2c
Dcdc2ctm1a(KOMP)Wtsi
HOM Early adult abnormal vertebrae morphology Shape of vertebrae
X-ray
WTSI
IMPC
8.75×10-05
Ppp1r42
Ppp1r42tm1a(KOMP)Wtsi
HOM   Early adult vertebral fusion Fusion of vertebrae
X-ray
WTSI
IMPC
8.79×10-05
Scn3b
Scn3btm1a(KOMP)Wtsi
HOM   Early adult vertebral fusion Fusion of vertebrae
X-ray
WTSI
IMPC
8.79×10-05
Bptf
Bptfem1(IMPC)Bay
HET   Early adult vertebral fusion Fusion of vertebrae
X-ray
BCM
IMPC
8.89×10-05
Hcar1
Hcar1em1(IMPC)Ccpcz
HOM   Early adult abnormal vertebral arch morphology Cervical processes
X-ray
CCP-IMG
IMPC
9.18×10-05
Wac
Wactm2b(EUCOMM)Wtsi
HET Early adult fusion of vertebral arches Fusion of processes
X-ray
WTSI
IMPC
9.73×10-05

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 The way we measure

 Phenotype associations stats

84.91% of tested genes with null mutations on a B6N genetic background have a phenotype association to abnormal vertebral column morphology (135/159)

34.81% females (55/158) 40.13% males (63/157)

Select a parameter    



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