Phenotype: abnormal vertebral column morphology

Definition
any structural anomaly of the complete structure forming the rostral-caudal axis of the skeleton formed from the alternating segments of vertebra and intervertebral discs which support the spinal cord
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with abnormal vertebral column morphology

Total number of significant genotype-phenotype associations: 318

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value
Asb5
Asb5em1(IMPC)Ccpcz
HOM Early adult abnormal caudal vertebrae morphology X-ray | Number of caudal vertebrae CCP-IMG | IMPC 0.00
Mta1
Mta1tm1a(EUCOMM)Wtsi
HET Early adult decreased caudal vertebrae number X-Ray | Number of caudal vertebrae WTSI | EuroPhenome 0.00
Mta1
Mta1tm1a(EUCOMM)Wtsi
HOM Early adult decreased caudal vertebrae number X-Ray | Number of caudal vertebrae WTSI | EuroPhenome 0.00
Mta1
Mta1tm1a(EUCOMM)Wtsi
HET Early adult decreased lumbar vertebrae number X-Ray | Number of lumbar vertebrae WTSI | EuroPhenome 0.00
Mta1
Mta1tm1a(EUCOMM)Wtsi
HOM Early adult decreased lumbar vertebrae number X-Ray | Number of lumbar vertebrae WTSI | EuroPhenome 0.00
Mta1
Mta1tm1a(EUCOMM)Wtsi
HET Early adult decreased sacral vertebrae number X-Ray | Number of pelvic vertebrae WTSI | EuroPhenome 0.00
Mta1
Mta1tm1a(EUCOMM)Wtsi
HOM Early adult decreased sacral vertebrae number X-Ray | Number of pelvic vertebrae WTSI | EuroPhenome 0.00
Mysm1
Mysm1tm1a(KOMP)Wtsi
HOM Early adult decreased caudal vertebrae number X-Ray | Number of caudal vertebrae WTSI | EuroPhenome 0.00
Mysm1
Mysm1tm1a(KOMP)Wtsi
HOM Early adult decreased sacral vertebrae number X-Ray | Number of pelvic vertebrae WTSI | EuroPhenome 0.00
Ube3c
Ube3ctm1b(EUCOMM)Hmgu
HOM Early adult abnormal caudal vertebrae morphology X-ray | Number of caudal vertebrae HMGU | IMPC 0.00
Duoxa2
Duoxa2tm1b(KOMP)Wtsi
HOM Early adult abnormal vertebral arch morphology X-ray | Sacral processes WTSI | IMPC 1.53×10-38
Trabd2b
Trabd2bem2(IMPC)Ccpcz
HOM Early adult abnormal vertebrae morphology X-ray | Shape of vertebrae CCP-IMG | IMPC 3.44×10-26
Pstpip2
Pstpip2em1(IMPC)Tcp
HOM Early adult abnormal vertebrae morphology X-ray | Shape of vertebrae TCP | IMPC 2.92×10-25
Ttc28
Ttc28tm1b(EUCOMM)Hmgu
HOM Early adult vertebral fusion X-ray | Fusion of vertebrae TCP | IMPC 6.48×10-24
Fbn2
Fbn2em1(IMPC)Rbrc
HOM Early adult abnormal vertebral arch morphology X-ray | Sacral processes RBRC | IMPC 1.45×10-21
Ap4e1
Ap4e1tm1b(KOMP)Wtsi
HOM Early adult abnormal spine curvature X-ray | Shape of spine KMPC | IMPC 3.10×10-20
Trabd2b
Trabd2bem2(IMPC)Ccpcz
HOM Early adult abnormal vertebral arch morphology X-ray | Thoracic processes CCP-IMG | IMPC 4.42×10-20
Duoxa2
Duoxa2tm1b(KOMP)Wtsi
HOM Early adult abnormal vertebrae morphology X-ray | Shape of vertebrae WTSI | IMPC 1.50×10-19
Sik3
Sik3tm1a(EUCOMM)Hmgu
HOM Early adult abnormal vertebrae morphology X-ray | Shape of vertebrae WTSI | IMPC 1.50×10-19
Sik3
Sik3tm1a(EUCOMM)Hmgu
HOM Early adult abnormal spine curvature X-ray | Shape of spine WTSI | IMPC 1.81×10-19
Slc29a1
Slc29a1tm2b(NCOM)Mfgc
HOM Early adult vertebral fusion X-ray | Fusion of vertebrae TCP | IMPC 2.98×10-19
Cbx5
Cbx5tm1a(EUCOMM)Wtsi
HOM Early adult vertebral transformation X-ray | Transitional vertebrae WTSI | IMPC 9.63×10-19
Ttc28
Ttc28tm1b(EUCOMM)Hmgu
HOM Early adult abnormal vertebrae morphology X-ray | Shape of vertebrae TCP | IMPC 2.52×10-18
Ap4e1
Ap4e1tm1b(KOMP)Wtsi
HOM Early adult kyphosis X-ray | Kyphosis KMPC | IMPC 8.67×10-18
Cyp27b1
Cyp27b1tm1b(EUCOMM)Hmgu
HOM Early adult abnormal vertebrae morphology X-ray | Shape of vertebrae TCP | IMPC 2.07×10-16
Cbx5
Cbx5tm1a(EUCOMM)Wtsi
HOM Early adult vertebral fusion X-ray | Fusion of vertebrae WTSI | IMPC 5.63×10-16
Tm9sf4
Tm9sf4tm1a(KOMP)Wtsi
HOM Early adult vertebral transformation X-ray | Transitional vertebrae WTSI | IMPC 1.88×10-15
Phex
Phexnot yet available
HOM Early adult abnormal vertebrae morphology X-Ray | Shape of vertebrae HMGU | EuroPhenome 3.95×10-15
Mysm1
Mysm1tm1a(KOMP)Wtsi
HOM Early adult abnormal vertebrae morphology X-Ray | Shape of vertebrae WTSI | EuroPhenome 1.04×10-14
Cbx5
Cbx5tm1a(EUCOMM)Wtsi
HOM Early adult fusion of vertebral arches X-ray | Fusion of processes WTSI | IMPC 1.39×10-14
Colec10
Colec10em2(IMPC)Tcp
HOM Early adult abnormal vertebrae morphology X-ray | Shape of vertebrae TCP | IMPC 7.41×10-14
Asb16
Asb16em1(IMPC)Ccpcz
HOM Early adult abnormal caudal vertebrae morphology X-ray | Number of caudal vertebrae CCP-IMG | IMPC 1.21×10-13
Jmjd1c
Jmjd1ctm1a(EUCOMM)Wtsi
HET Early adult vertebral transformation X-ray | Transitional vertebrae WTSI | IMPC 1.69×10-13
Asb5
Asb5em1(IMPC)Ccpcz
HOM Early adult increased caudal vertebrae number X-ray | Number of caudal vertebrae CCP-IMG | IMPC 4.08×10-13
Cog6
Cog6tm1a(EUCOMM)Wtsi
HOM Early adult vertebral transformation X-ray | Transitional vertebrae WTSI | IMPC 1.06×10-11
Uchl1
Uchl1tm1b(EUCOMM)Hmgu
HET Early adult abnormal spine curvature X-ray | Shape of spine MRC Harwell | IMPC 1.63×10-11
Aff3
Aff3tm1a(EUCOMM)Wtsi
HOM Early adult abnormal vertebral arch morphology X-ray | Thoracic processes WTSI | IMPC 1.79×10-11
Mex3b
Mex3btm1b(KOMP)Wtsi
HOM Early adult abnormal vertebral arch morphology X-ray | Lumbar processes CCP-IMG | IMPC 2.72×10-11
Slc20a2
Slc20a2tm1a(EUCOMM)Wtsi
HOM Early adult kyphosis X-ray | Kyphosis WTSI | IMPC 8.52×10-11
Wdr37
Wdr37tm1a(KOMP)Wtsi
HOM Early adult fusion of vertebral arches X-ray | Fusion of processes WTSI | IMPC 9.74×10-11
Aff3
Aff3tm1a(EUCOMM)Wtsi
HET Early adult abnormal vertebral arch morphology X-ray | Thoracic processes WTSI | IMPC 1.13×10-10
Mindy1
Mindy1tm1b(EUCOMM)Wtsi
HOM Early adult abnormal spine curvature X-ray | Shape of spine MRC Harwell | IMPC 1.44×10-10
Sik3
Sik3tm1a(EUCOMM)Hmgu
HOM Early adult kyphosis X-ray | Kyphosis WTSI | IMPC 4.01×10-10
Mex3b
Mex3btm1b(KOMP)Wtsi
HOM Early adult vertebral transformation X-ray | Transitional vertebrae CCP-IMG | IMPC 7.74×10-10
Ccnd2
Ccnd2tm1b(KOMP)Mbp
HOM Early adult abnormal spine curvature X-ray | Shape of spine MRC Harwell | IMPC 1.03×10-09
Dnase1l2
Dnase1l2tm1.1(KOMP)Wtsi
HOM Early adult vertebral fusion X-ray | Fusion of vertebrae MRC Harwell | IMPC 1.09×10-09
Slc20a2
Slc20a2tm1a(EUCOMM)Wtsi
HOM Early adult abnormal spine curvature X-ray | Shape of spine WTSI | IMPC 1.95×10-09
Mex3b
Mex3btm1b(KOMP)Wtsi
HOM Early adult abnormal vertebrae morphology X-ray | Shape of vertebrae CCP-IMG | IMPC 2.48×10-09
Dele1
Dele1em2(IMPC)Ccpcz
HOM Early adult abnormal caudal vertebrae morphology X-ray | Number of caudal vertebrae CCP-IMG | IMPC 2.92×10-09
Gbx1
Gbx1Gbx1
HOM Early adult vertebral fusion X-Ray | Fusion of vertebrae ICS | EuroPhenome 3.58×10-09
Skida1
Skida1tm1(KOMP)Wtsi
HET Early adult abnormal vertebral arch morphology X-ray | Thoracic processes WTSI | IMPC 3.90×10-09
Aff3
Aff3tm1a(EUCOMM)Wtsi
HOM Early adult fusion of vertebral arches X-ray | Fusion of processes WTSI | IMPC 5.23×10-09
Il2ra
Il2ratm1b(EUCOMM)Wtsi
HOM Early adult abnormal vertebrae morphology X-ray | Shape of vertebrae ICS | IMPC 1.20×10-08
Wdr37
Wdr37tm1a(KOMP)Wtsi
HOM Early adult vertebral fusion X-ray | Fusion of vertebrae WTSI | IMPC 1.42×10-08
Mbd1
Mbd1em1(IMPC)Wtsi
HOM Early adult vertebral transformation X-ray | Transitional vertebrae WTSI | IMPC 1.68×10-08
Asb16
Asb16em1(IMPC)Ccpcz
HOM Early adult increased caudal vertebrae number X-ray | Number of caudal vertebrae CCP-IMG | IMPC 2.22×10-08
Trim9
Trim9em1(IMPC)Ccpcz
HOM Early adult abnormal vertebral arch morphology X-ray | Cervical processes CCP-IMG | IMPC 2.57×10-08
Ddi2
Ddi2tm1b(EUCOMM)Hmgu
HET Early adult abnormal spine curvature X-ray | Shape of spine CCP-IMG | IMPC 4.22×10-08
Tent5a
Tent5aem1(IMPC)Ccpcz
HOM Early adult abnormal spine curvature X-ray | Shape of spine CCP-IMG | IMPC 4.22×10-08
Gyg
Gygtm1b(KOMP)Wtsi
HET Early adult vertebral fusion X-ray | Fusion of vertebrae BCM | IMPC 6.54×10-08
Snx5
Snx5Snx5
HOM Early adult abnormal vertebrae morphology X-Ray | Shape of vertebrae ICS | EuroPhenome 7.31×10-08
Gna11
Gna11tm1b(EUCOMM)Wtsi
HOM Early adult vertebral fusion X-ray | Fusion of vertebrae MRC Harwell | IMPC 8.87×10-08
4932438H23Rik
4932438H23Riktm1a(EUCOMM)Wtsi
HOM Early adult abnormal vertebral arch morphology X-ray | Thoracic processes WTSI | IMPC 9.29×10-08
Xbp1
Xbp1tm1a(EUCOMM)Wtsi
HET Early adult abnormal vertebral arch morphology X-ray | Thoracic processes WTSI | IMPC 9.29×10-08
Il12a
Il12atm1b(EUCOMM)Hmgu
HOM Early adult vertebral fusion X-ray | Fusion of vertebrae MRC Harwell | IMPC 1.47×10-07
Pdss2
Pdss2tm1b(EUCOMM)Hmgu
HET Early adult vertebral fusion X-ray | Fusion of vertebrae MRC Harwell | IMPC 1.47×10-07
Tram2
Tram2tm1a(KOMP)Wtsi
HOM Early adult abnormal vertebral arch morphology X-ray | Cervical processes WTSI | IMPC 1.92×10-07
Dnase1l2
Dnase1l2tm1.1(KOMP)Wtsi
HOM Early adult fusion of vertebral arches X-ray | Fusion of processes WTSI | IMPC 2.27×10-07
1110059G10Rik
1110059G10Riktm1a(KOMP)Wtsi
HOM Early adult vertebral transformation X-ray | Transitional vertebrae WTSI | IMPC 2.33×10-07
Aff3
Aff3tm1a(EUCOMM)Wtsi
HOM Early adult vertebral transformation X-ray | Transitional vertebrae WTSI | IMPC 2.33×10-07
Tent5a
Tent5aem1(IMPC)Ccpcz
HOM Early adult scoliosis X-ray | Scoliosis CCP-IMG | IMPC 2.42×10-07
Ube2g1
Ube2g1tm1b(EUCOMM)Hmgu
HOM Early adult vertebral fusion X-ray | Fusion of vertebrae RBRC | IMPC 2.60×10-07
Tram2
Tram2tm1a(KOMP)Wtsi
HOM Early adult kyphosis X-ray | Kyphosis WTSI | IMPC 3.22×10-07
Ap4e1
Ap4e1tm1b(KOMP)Wtsi
HOM Early adult lordosis X-ray | Lordosis KMPC | IMPC 4.00×10-07
Kdm7a
Kdm7atm1a(EUCOMM)Wtsi
HOM Early adult vertebral transformation X-ray | Transitional vertebrae WTSI | IMPC 4.49×10-07
Dbn1
Dbn1tm1b(KOMP)Wtsi
HET Early adult abnormal caudal vertebrae morphology X-ray | Number of caudal vertebrae CCP-IMG | IMPC 5.20×10-07
Prkab1
Prkab1tm1b(KOMP)Wtsi
HOM Early adult kyphosis X-ray | Kyphosis KMPC | IMPC 5.85×10-07
Prkab1
Prkab1tm1b(KOMP)Wtsi
HOM Early adult abnormal spine curvature X-ray | Shape of spine KMPC | IMPC 6.08×10-07
Setd3
Setd3tm1.1(NCOM)Mfgc
HOM Early adult vertebral fusion X-ray | Fusion of vertebrae TCP | IMPC 6.83×10-07
Sel1l
Sel1ltm1e(KOMP)Wtsi
HET Early adult vertebral fusion X-ray | Fusion of vertebrae WTSI | IMPC 7.80×10-07
Ushbp1
Ushbp1tm1a(EUCOMM)Wtsi
HOM Early adult vertebral fusion X-ray | Fusion of vertebrae WTSI | IMPC 7.80×10-07
Supt5
Supt5tm2a(KOMP)Wtsi
HET Early adult vertebral transformation X-ray | Transitional vertebrae WTSI | IMPC 8.12×10-07
Sirt3
Sirt3tm1b(EUCOMM)Wtsi
HOM Early adult vertebral fusion X-ray | Fusion of vertebrae MRC Harwell | IMPC 9.33×10-07
Ddi2
Ddi2tm1b(EUCOMM)Hmgu
HET Early adult abnormal caudal vertebrae morphology X-ray | Number of caudal vertebrae CCP-IMG | IMPC 1.36×10-06
Dph6
Dph6tm1a(KOMP)Wtsi
HOM Early adult vertebral transformation X-ray | Transitional vertebrae WTSI | IMPC 1.57×10-06
L3mbtl2
L3mbtl2tm2a(EUCOMM)Wtsi
HET Early adult vertebral transformation X-ray | Transitional vertebrae WTSI | IMPC 1.57×10-06
Slc25a30
Slc25a30tm1a(EUCOMM)Wtsi
HOM Early adult abnormal vertebral arch morphology X-ray | Thoracic processes WTSI | IMPC 1.62×10-06
Pld5
Pld5tm1b(KOMP)Wtsi
HOM Early adult abnormal vertebral arch morphology X-ray | Thoracic processes WTSI | IMPC 1.84×10-06
Ddi2
Ddi2tm1b(EUCOMM)Hmgu
HET Early adult decreased caudal vertebrae number X-ray | Number of caudal vertebrae CCP-IMG | IMPC 2.10×10-06
Klk13
Klk13em1(IMPC)Ccpcz
HOM Early adult abnormal caudal vertebrae morphology X-ray | Number of caudal vertebrae CCP-IMG | IMPC 2.80×10-06
Dnase1l2
Dnase1l2tm1.1(KOMP)Wtsi
HOM Early adult abnormal vertebrae morphology X-ray | Shape of vertebrae WTSI | MGP 2.87×10-06
Tram2
Tram2tm1a(KOMP)Wtsi
HOM Early adult abnormal spine curvature X-ray | Shape of spine WTSI | IMPC 3.10×10-06
Barx2
Barx2tm1b(EUCOMM)Hmgu
HOM Early adult abnormal vertebrae morphology X-ray | Shape of vertebrae MRC Harwell | IMPC 3.43×10-06
Ccnd2
Ccnd2tm1b(KOMP)Mbp
HOM Late adult abnormal spine curvature X-ray | Shape of spine MRC Harwell | IMPC 3.61×10-06
Brd2
Brd2em1(IMPC)Wtsi
HET Early adult abnormal vertebral arch morphology X-ray | Cervical processes WTSI | IMPC 3.75×10-06
Cpt2
Cpt2tm1b(KOMP)Wtsi
HET Early adult abnormal vertebrae morphology X-ray | Shape of vertebrae WTSI | IMPC 3.81×10-06
Mysm1
Mysm1tm1a(KOMP)Wtsi
HOM Early adult vertebral fusion X-Ray | Fusion of vertebrae WTSI | EuroPhenome 4.01×10-06
Spopl
Spopltm1a(EUCOMM)Wtsi
HOM Early adult abnormal vertebral arch morphology X-ray | Thoracic processes WTSI | IMPC 4.10×10-06
Btbd3
Btbd3tm1b(EUCOMM)Hmgu
HOM Early adult abnormal vertebrae morphology X-ray | Shape of vertebrae CCP-IMG | IMPC 5.05×10-06
Tent4a
Tent4atm1b(EUCOMM)Hmgu
HOM Early adult abnormal vertebrae morphology X-ray | Shape of vertebrae CCP-IMG | IMPC 5.05×10-06
Fbn2
Fbn2em1(IMPC)Rbrc
HOM Early adult vertebral fusion X-ray | Fusion of vertebrae RBRC | IMPC 5.37×10-06
Ube2g1
Ube2g1tm1b(EUCOMM)Hmgu
HOM Early adult fusion of vertebral arches X-ray | Fusion of processes RBRC | IMPC 5.70×10-06
Abca4
Abca4tm1a(EUCOMM)Wtsi
HOM Early adult abnormal caudal vertebrae morphology Vertebral Microradiography | Vertebral Height WTSI | IMPC 5.79×10-06
Mtch2
Mtch2tm1b(EUCOMM)Hmgu
HET Early adult abnormal vertebrae morphology X-ray | Shape of vertebrae MRC Harwell | IMPC 6.25×10-06
Setmar
Setmartm1a(EUCOMM)Wtsi
HOM Early adult abnormal vertebrae morphology X-ray | Shape of vertebrae WTSI | EuroPhenome 6.42×10-06
Hcar1
Hcar1em1(IMPC)Ccpcz
HOM Early adult vertebral transformation X-ray | Transitional vertebrae CCP-IMG | IMPC 7.32×10-06
Ap4e1
Ap4e1tm1b(KOMP)Wtsi
HOM Early adult abnormal vertebral arch morphology X-ray | Lumbar processes CCP-IMG | IMPC 7.97×10-06
Ropn1l
Ropn1ltm1b(EUCOMM)Wtsi
HOM Early adult kyphosis X-ray | Kyphosis WTSI | IMPC 9.77×10-06
Wdr37
Wdr37tm1a(KOMP)Wtsi
HOM Early adult kyphosis X-ray | Kyphosis WTSI | IMPC 9.77×10-06
Slc25a4
Slc25a4tm1a(EUCOMM)Wtsi
HOM Early adult fusion of vertebral arches X-ray | Fusion of processes WTSI | IMPC 1.02×10-05
Xndc1
Xndc1tm1a(EUCOMM)Wtsi
HOM Early adult fusion of vertebral arches X-ray | Fusion of processes WTSI | IMPC 1.02×10-05
Mir129-2
Mir129-2em1(IMPC)KMPC
HOM Late adult abnormal spine curvature X-ray | Shape of spine KMPC | IMPC 1.03×10-05
Tmem273
Tmem273em1(IMPC)Ccpcz
HOM Early adult vertebral transformation X-ray | Transitional vertebrae CCP-IMG | IMPC 1.11×10-05
Arpc1b
Arpc1btm1a(EUCOMM)Wtsi
HOM Early adult vertebral fusion X-ray | Fusion of vertebrae WTSI | IMPC 1.21×10-05
Abca4
Abca4tm1a(EUCOMM)Wtsi
HOM Early adult vertebral fusion X-ray | Fusion of vertebrae WTSI | IMPC 1.25×10-05
Fggy
Fggytm1a(KOMP)Wtsi
HOM Early adult vertebral fusion X-ray | Fusion of vertebrae WTSI | IMPC 1.25×10-05
Gm13547
Gm13547tm1a(KOMP)Wtsi
HOM Early adult vertebral fusion X-ray | Fusion of vertebrae WTSI | IMPC 1.25×10-05
Os9
Os9tm1a(EUCOMM)Wtsi
HOM Early adult vertebral fusion X-ray | Fusion of vertebrae WTSI | IMPC 1.25×10-05
Ppp1r42
Ppp1r42tm1a(KOMP)Wtsi
HOM Early adult vertebral fusion X-ray | Fusion of vertebrae WTSI | IMPC 1.25×10-05
Zscan2
Zscan2tm1a(KOMP)Wtsi
HOM Early adult vertebral fusion X-ray | Fusion of vertebrae WTSI | IMPC 1.25×10-05
Prkab1
Prkab1tm1b(KOMP)Wtsi
HOM Early adult abnormal caudal vertebrae morphology X-ray | Number of caudal vertebrae CCP-IMG | IMPC 1.39×10-05
Mysm1
Mysm1tm1a(KOMP)Wtsi
HET Early adult abnormal vertebral arch morphology X-Ray | Processes on vertebrae WTSI | EuroPhenome 1.42×10-05
Plekhm1
Plekhm1tm1b(EUCOMM)Hmgu
HOM Early adult abnormal vertebrae morphology X-ray | Shape of vertebrae TCP | IMPC 1.58×10-05
Btbd3
Btbd3tm1b(EUCOMM)Hmgu
HOM Early adult abnormal vertebral arch morphology X-ray | Thoracic processes CCP-IMG | IMPC 1.67×10-05
Trim15
Trim15tm1b(EUCOMM)Hmgu
HOM Early adult lordosis X-ray | Lordosis CCP-IMG | IMPC 1.73×10-05
Nisch
Nischtm1b(EUCOMM)Hmgu
HOM Early adult abnormal spine curvature X-ray | Shape of spine MRC Harwell | IMPC 1.76×10-05
Mbd1
Mbd1em1(IMPC)Wtsi
HOM Early adult lordosis X-ray | Lordosis WTSI | IMPC 1.83×10-05
Dele1
Dele1em2(IMPC)Ccpcz
HOM Early adult abnormal vertebral arch morphology X-ray | Cervical processes CCP-IMG | IMPC 1.95×10-05
Gldc
Gldctm1a(EUCOMM)Wtsi
HET Early adult abnormal vertebral arch morphology X-ray | Thoracic processes WTSI | IMPC 2.13×10-05
Ralb
Ralbtm1a(EUCOMM)Wtsi
HOM Early adult abnormal vertebral arch morphology X-ray | Thoracic processes WTSI | IMPC 2.13×10-05
Sh2d5
Sh2d5tm1a(EUCOMM)Wtsi
HOM Early adult abnormal vertebral arch morphology X-ray | Thoracic processes WTSI | IMPC 2.13×10-05
Vps53
Vps53tm1a(KOMP)Wtsi
HET Early adult abnormal vertebral arch morphology X-ray | Thoracic processes WTSI | IMPC 2.13×10-05
Dbn1
Dbn1tm1b(KOMP)Wtsi
HET Early adult abnormal vertebrae morphology X-ray | Shape of vertebrae MRC Harwell | IMPC 2.14×10-05
Rhou
Rhoutm1a(KOMP)Wtsi
HOM Early adult vertebral fusion X-ray | Fusion of vertebrae WTSI | MGP 2.29×10-05
Kcnv2
Kcnv2tm1Wtsi
HOM Early adult kyphosis X-ray | Kyphosis WTSI | IMPC 2.32×10-05
Coa6
Coa6em1(IMPC)Ccpcz
HET Early adult abnormal vertebral arch morphology X-ray | Processes on vertebrae CCP-IMG | IMPC 2.93×10-05
Arpc1b
Arpc1btm1a(EUCOMM)Wtsi
HOM Early adult fusion of vertebral arches X-ray | Fusion of processes WTSI | IMPC 2.97×10-05
Marchf6
Marchf6tm1b(EUCOMM)Hmgu
HOM Early adult abnormal caudal vertebrae morphology X-ray | Number of caudal vertebrae CCP-IMG | IMPC 3.09×10-05
Marchf8
Marchf8em2(IMPC)Ccpcz
HOM Early adult kyphosis X-ray | Kyphosis CCP-IMG | IMPC 3.49×10-05
Klf7
Klf7tm1b(EUCOMM)Hmgu
HET Early adult abnormal vertebrae morphology X-ray | Shape of vertebrae MRC Harwell | IMPC 3.55×10-05
Lrrk1
Lrrk1tm1b(KOMP)Wtsi
HOM Early adult abnormal vertebrae morphology X-ray | Shape of vertebrae MRC Harwell | IMPC 3.55×10-05
Notch1
Notch1tm1b(EUCOMM)Hmgu
HET Early adult abnormal vertebrae morphology X-ray | Shape of vertebrae MRC Harwell | IMPC 3.55×10-05
Rlim
Rlimem1(IMPC)Rbrc
HEM Early adult fusion of vertebral arches X-ray | Fusion of processes RBRC | IMPC 3.66×10-05
Pex3
Pex3tm1a(EUCOMM)Wtsi
HOM Early adult abnormal vertebrae morphology X-ray | Shape of vertebrae WTSI | MGP 4.16×10-05
Lyplal1
Lyplal1tm1a(KOMP)Wtsi
HOM Early adult vertebral fusion X-ray | Fusion of vertebrae WTSI | IMPC 4.26×10-05
Setd5
Setd5tm1a(EUCOMM)Wtsi
HET Early adult vertebral fusion X-ray | Fusion of vertebrae WTSI | IMPC 4.26×10-05
Dbn1
Dbn1tm1b(KOMP)Wtsi
HET Early adult decreased caudal vertebrae number X-ray | Number of caudal vertebrae CCP-IMG | IMPC 4.31×10-05
Epc2
Epc2tm1e(EUCOMM)Wtsi
HET Early adult abnormal vertebral arch morphology X-Ray | Processes on vertebrae WTSI | EuroPhenome 4.47×10-05
Dcbld2
Dcbld2tm1a(KOMP)Wtsi
HOM Early adult abnormal vertebral arch morphology X-ray | Cervical processes WTSI | IMPC 4.54×10-05
Glg1
Glg1tm1a(KOMP)Wtsi
HET Early adult abnormal vertebral arch morphology X-ray | Cervical processes WTSI | IMPC 4.54×10-05
Kera
Keraem1(IMPC)Wtsi
HOM Early adult abnormal vertebral arch morphology X-ray | Cervical processes WTSI | IMPC 4.54×10-05
Selenok
Selenoktm1b(EUCOMM)Wtsi
HOM Early adult abnormal vertebral arch morphology X-ray | Cervical processes WTSI | IMPC 4.54×10-05
Wdtc1
Wdtc1tm1a(KOMP)Wtsi
HOM Early adult abnormal vertebral arch morphology X-ray | Cervical processes WTSI | IMPC 4.54×10-05
Mpp6
Mpp6em1(IMPC)Rbrc
HOM Early adult fusion of vertebral arches X-ray | Fusion of processes RBRC | IMPC 4.85×10-05
Mir129-2
Mir129-2em1(IMPC)KMPC
HOM Late adult abnormal vertebral arch morphology X-ray | Processes on vertebrae KMPC | IMPC 5.05×10-05
Tmc6
Tmc6tm1a(EUCOMM)Wtsi
HOM Early adult vertebral fusion X-ray | Fusion of vertebrae WTSI | IMPC 5.39×10-05
Cfap161
Cfap161em1(IMPC)Ccpcz
HOM Early adult kyphosis X-ray | Kyphosis CCP-IMG | IMPC 6.16×10-05
Ddi2
Ddi2tm1b(EUCOMM)Hmgu
HET Early adult kyphosis X-ray | Kyphosis CCP-IMG | IMPC 6.16×10-05
Ap4e1
Ap4e1tm1b(KOMP)Wtsi
HOM Early adult abnormal vertebrae morphology X-ray | Shape of vertebrae CCP-IMG | IMPC 6.42×10-05
Tmem273
Tmem273em1(IMPC)Ccpcz
HOM Early adult abnormal vertebrae morphology X-ray | Shape of vertebrae CCP-IMG | IMPC 6.42×10-05
Mau2
Mau2tm1b(KOMP)Wtsi
HET Early adult vertebral transformation X-ray | Transitional vertebrae WTSI | IMPC 6.47×10-05
Scaf11
Scaf11em1(IMPC)Wtsi
HOM Early adult vertebral transformation X-ray | Transitional vertebrae WTSI | IMPC 6.47×10-05
Dnase1l2
Dnase1l2tm1.1(KOMP)Wtsi
HOM Early adult abnormal spine curvature X-ray | Shape of spine WTSI | IMPC 6.63×10-05
H2-Eb1
H2-Eb1tm1a(KOMP)Wtsi
HOM Early adult abnormal spine curvature X-ray | Shape of spine WTSI | IMPC 6.63×10-05
Pabpc4
Pabpc4tm1a(KOMP)Wtsi
HOM Early adult abnormal spine curvature X-ray | Shape of spine WTSI | IMPC 6.63×10-05
Ropn1l
Ropn1ltm1b(EUCOMM)Wtsi
HOM Early adult abnormal spine curvature X-ray | Shape of spine WTSI | IMPC 6.63×10-05
Selenok
Selenoktm1b(EUCOMM)Wtsi
HOM Early adult abnormal spine curvature X-ray | Shape of spine WTSI | IMPC 6.63×10-05
Wdr37
Wdr37tm1a(KOMP)Wtsi
HOM Early adult abnormal spine curvature X-ray | Shape of spine WTSI | IMPC 6.63×10-05
Cnpy2
Cnpy2em1(IMPC)Wtsi
HOM Early adult abnormal vertebrae morphology X-ray | Shape of vertebrae CCP-IMG | IMPC 6.81×10-05
Btbd3
Btbd3tm1b(EUCOMM)Hmgu
HOM Early adult abnormal spine curvature X-ray | Shape of spine CCP-IMG | IMPC 8.10×10-05
Cluh
Cluhem1(IMPC)Ccpcz
HET Early adult abnormal spine curvature X-ray | Shape of spine CCP-IMG | IMPC 8.10×10-05
Asb5
Asb5em1(IMPC)Ccpcz
HOM Early adult abnormal vertebrae morphology X-ray | Shape of vertebrae CCP-IMG | IMPC 8.40×10-05
Bptf
Bptfem1(IMPC)Bay
HET Early adult vertebral fusion X-ray | Fusion of vertebrae BCM | IMPC 8.62×10-05
Scn3b
Scn3btm1a(KOMP)Wtsi
HOM Early adult vertebral fusion X-ray | Fusion of vertebrae WTSI | IMPC 9.45×10-05

Download data as:   TSV   XLS

 The way we measure

 Phenotype associations stats

100.00% of tested genes with null mutations on a B6N genetic background have a phenotype association to abnormal vertebral column morphology (116/116)

38.26% females (44/115) 51.30% males (59/115)

Select a parameter    



The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter