IMPC Gene variants with abnormal vertebral arch morphology
Total number of significant genotype-phenotype associations: 80
Gene / Allele | Zygosity | Sex | Life Stage | Phenotype | Parameter | Phenotyping Center |
P Value |
---|---|---|---|---|---|---|---|
Duoxa2 Duoxa2tm1b(KOMP)Wtsi |
HOM | Early adult | abnormal vertebral arch morphology | Lumbar processes X-ray |
WTSI IMPC |
3.14×10-19 | |
Lrig3 Lrig3em1(IMPC)Ccpcz |
HOM | Early adult | abnormal vertebral arch morphology | Thoracic processes X-ray |
CCP-IMG IMPC |
4.42×10-12 | |
Trabd2b Trabd2bem2(IMPC)Ccpcz |
HOM | Early adult | abnormal vertebral arch morphology | Thoracic processes X-ray |
CCP-IMG IMPC |
2.09×10-11 | |
Calb1 Calb1em1(IMPC)Ccpcz |
HOM | Early adult | abnormal vertebral arch morphology | Thoracic processes X-ray |
CCP-IMG IMPC |
3.44×10-11 | |
Fbn2 Fbn2em1(IMPC)Rbrc |
HOM | Early adult | abnormal vertebral arch morphology | Sacral processes X-ray |
RBRC IMPC |
6.97×10-11 | |
Trim9 Trim9em1(IMPC)Ccpcz |
HOM | Early adult | abnormal vertebral arch morphology | Cervical processes X-ray |
CCP-IMG IMPC |
5.74×10-09 | |
Mex3b Mex3btm1b(KOMP)Wtsi |
HOM | Early adult | abnormal vertebral arch morphology | Lumbar processes X-ray |
CCP-IMG IMPC |
1.05×10-08 | |
Phex Phexnot yet available |
HOM | Early adult | abnormal vertebral arch morphology | Processes on vertebrae X-Ray |
HMGU EuroPhenome |
4.04×10-08 | |
Cbx5 Cbx5tm1a(EUCOMM)Wtsi |
HOM | Early adult | fusion of vertebral arches | Fusion of processes X-ray |
WTSI IMPC |
4.88×10-08 | |
Aff3 Aff3tm1a(EUCOMM)Wtsi |
HET | Early adult | abnormal vertebral arch morphology | Thoracic processes X-ray |
WTSI IMPC |
5.92×10-08 | |
4932438H23Rik 4932438H23Riktm1a(EUCOMM)Wtsi |
HOM | Early adult | abnormal vertebral arch morphology | Thoracic processes X-ray |
WTSI IMPC |
1.02×10-07 | |
Xbp1 Xbp1tm1a(EUCOMM)Wtsi |
HET | Early adult | abnormal vertebral arch morphology | Thoracic processes X-ray |
WTSI IMPC |
1.02×10-07 | |
Dnase1l2 Dnase1l2tm1.1(KOMP)Wtsi |
HOM | Early adult | fusion of vertebral arches | Fusion of processes X-ray |
WTSI IMPC |
1.67×10-07 | |
Wdr37 Wdr37tm1a(KOMP)Wtsi |
HOM | Early adult | fusion of vertebral arches | Fusion of processes X-ray |
WTSI IMPC |
1.67×10-07 | |
Tram2 Tram2tm1a(KOMP)Wtsi |
HOM | Early adult | abnormal vertebral arch morphology | Cervical processes X-ray |
WTSI IMPC |
2.10×10-07 | |
Cer1 Cer1em1(IMPC)Ccpcz |
HOM | Early adult | abnormal vertebral arch morphology | Thoracic processes X-ray |
CCP-IMG IMPC |
3.01×10-07 | |
Dcaf15 Dcaf15tm1a(EUCOMM)Hmgu |
HOM | Early adult | abnormal vertebral arch morphology | Thoracic processes X-ray |
CCP-IMG IMPC |
3.01×10-07 | |
Aff3 Aff3tm1a(EUCOMM)Wtsi |
HOM | Early adult | abnormal vertebral arch morphology | Thoracic processes X-ray |
WTSI IMPC |
3.07×10-07 | |
Prss48 Prss48em1(IMPC)Ccpcz |
HOM | Early adult | abnormal vertebral arch morphology | Thoracic processes X-ray |
CCP-IMG IMPC |
1.11×10-06 | |
Cul9 Cul9em1(IMPC)Ccpcz |
HOM | Early adult | abnormal vertebral arch morphology | Thoracic processes X-ray |
CCP-IMG IMPC |
1.44×10-06 | |
Brinp3 Brinp3em1(IMPC)Ccpcz |
HOM | Early adult | abnormal vertebral arch morphology | Thoracic processes X-ray |
CCP-IMG IMPC |
1.74×10-06 | |
Gal3st1 Gal3st1em1(IMPC)Rbrc |
HOM | Early adult | abnormal vertebral arch morphology | Processes on vertebrae X-ray |
RBRC IMPC |
2.39×10-06 | |
Twist1 Twist1em1(IMPC)Rbrc |
HET | Early adult | abnormal vertebral arch morphology | Processes on vertebrae X-ray |
RBRC IMPC |
2.39×10-06 | |
Zfhx2 Zfhx2em1(IMPC)Rbrc |
HOM | Early adult | abnormal vertebral arch morphology | Processes on vertebrae X-ray |
RBRC IMPC |
2.39×10-06 | |
Runx2 Runx2em1(IMPC)Rbrc |
HET | Early adult | abnormal vertebral arch morphology | Cervical processes X-ray |
RBRC IMPC |
3.02×10-06 | |
Spred1 Spred1em1(IMPC)Ccpcz |
HOM | Early adult | fusion of vertebral arches | Fusion of processes X-ray |
CCP-IMG IMPC |
3.15×10-06 | |
Spopl Spopltm1a(EUCOMM)Wtsi |
HOM | Early adult | abnormal vertebral arch morphology | Thoracic processes X-ray |
WTSI IMPC |
4.03×10-06 | |
Brd2 Brd2em1(IMPC)Wtsi |
HET | Early adult | abnormal vertebral arch morphology | Cervical processes X-ray |
WTSI IMPC |
4.06×10-06 | |
Dele1 Dele1em2(IMPC)Ccpcz |
HOM | Early adult | abnormal vertebral arch morphology | Cervical processes X-ray |
CCP-IMG IMPC |
5.00×10-06 | |
Fgf20 Fgf20em1(IMPC)Ccpcz |
HOM | Early adult | fusion of vertebral arches | Fusion of processes X-ray |
CCP-IMG IMPC |
5.60×10-06 | |
Ube2g1 Ube2g1tm1b(EUCOMM)Hmgu |
HOM | Early adult | fusion of vertebral arches | Fusion of processes X-ray |
RBRC IMPC |
5.70×10-06 | |
Aff3 Aff3tm1a(EUCOMM)Wtsi |
HOM | Early adult | fusion of vertebral arches | Fusion of processes X-ray |
WTSI IMPC |
7.64×10-06 | |
Slc25a4 Slc25a4tm1a(EUCOMM)Wtsi |
HOM | Early adult | fusion of vertebral arches | Fusion of processes X-ray |
WTSI IMPC |
9.17×10-06 | |
Xndc1 Xndc1tm1a(EUCOMM)Wtsi |
HOM | Early adult | fusion of vertebral arches | Fusion of processes X-ray |
WTSI IMPC |
9.17×10-06 | |
Mysm1 Mysm1tm1a(KOMP)Wtsi |
HET | Early adult | abnormal vertebral arch morphology | Processes on vertebrae X-Ray |
WTSI EuroPhenome |
1.42×10-05 | |
Ap4e1 Ap4e1tm1b(KOMP)Wtsi |
HOM | Early adult | abnormal vertebral arch morphology | Lumbar processes X-ray |
CCP-IMG IMPC |
1.49×10-05 | |
Btbd3 Btbd3tm1b(EUCOMM)Hmgu |
HOM | Early adult | abnormal vertebral arch morphology | Thoracic processes X-ray |
CCP-IMG IMPC |
1.51×10-05 | |
Amelx Amelxem1(IMPC)Ccpcz |
HET | Early adult | abnormal vertebral arch morphology | Processes on vertebrae X-ray |
CCP-IMG IMPC |
1.52×10-05 | |
Skida1 Skida1tm1(KOMP)Wtsi |
HET | Early adult | abnormal vertebral arch morphology | Thoracic processes X-ray |
WTSI IMPC |
1.62×10-05 | |
Slc25a30 Slc25a30tm1a(EUCOMM)Wtsi |
HOM | Early adult | abnormal vertebral arch morphology | Thoracic processes X-ray |
WTSI IMPC |
1.62×10-05 | |
Pld5 Pld5tm1b(KOMP)Wtsi |
HOM | Early adult | abnormal vertebral arch morphology | Thoracic processes X-ray |
WTSI IMPC |
1.74×10-05 | |
Mir129-2 Mir129-2em1(IMPC)Kmpc |
HOM | Late adult | abnormal vertebral arch morphology | Processes on vertebrae X-ray |
KMPC IMPC |
2.03×10-05 | |
Gldc Gldctm1a(EUCOMM)Wtsi |
HET | Early adult | abnormal vertebral arch morphology | Thoracic processes X-ray |
WTSI IMPC |
2.29×10-05 | |
Ralb Ralbtm1a(EUCOMM)Wtsi |
HOM | Early adult | abnormal vertebral arch morphology | Thoracic processes X-ray |
WTSI IMPC |
2.29×10-05 | |
Sh2d5 Sh2d5tm1a(EUCOMM)Wtsi |
HOM | Early adult | abnormal vertebral arch morphology | Thoracic processes X-ray |
WTSI IMPC |
2.29×10-05 | |
Vps53 Vps53tm1a(KOMP)Wtsi |
HET | Early adult | abnormal vertebral arch morphology | Thoracic processes X-ray |
WTSI IMPC |
2.29×10-05 | |
C9orf72 C9orf72tm1.1(KOMP)Mbp |
HOM | Early adult | abnormal vertebral arch morphology | Processes on vertebrae X-ray |
UC Davis IMPC |
2.67×10-05 | |
Fgf20 Fgf20em1(IMPC)Ccpcz |
HOM | Early adult | abnormal vertebral arch morphology | Processes on vertebrae X-ray |
CCP-IMG IMPC |
3.31×10-05 | |
Rlim Rlimem1(IMPC)Rbrc |
HEM | Early adult | fusion of vertebral arches | Fusion of processes X-ray |
RBRC IMPC |
3.45×10-05 | |
Arpc1b Arpc1btm1a(EUCOMM)Wtsi |
HOM | Early adult | fusion of vertebral arches | Fusion of processes X-ray |
WTSI IMPC |
3.70×10-05 | |
Tent4a Tent4atm1b(EUCOMM)Hmgu |
HOM | Early adult | abnormal vertebral arch morphology | Cervical processes X-ray |
CCP-IMG IMPC |
3.95×10-05 | |
Spred1 Spred1em1(IMPC)Ccpcz |
HOM | Early adult | abnormal vertebral arch morphology | Processes on vertebrae X-ray |
CCP-IMG IMPC |
4.21×10-05 | |
Pals2 Pals2em1(IMPC)Rbrc |
HOM | Early adult | fusion of vertebral arches | Fusion of processes X-ray |
RBRC IMPC |
4.49×10-05 | |
Dcbld2 Dcbld2tm1a(KOMP)Wtsi |
HOM | Early adult | abnormal vertebral arch morphology | Cervical processes X-ray |
WTSI IMPC |
4.87×10-05 | |
Glg1 Glg1tm1a(KOMP)Wtsi |
HET | Early adult | abnormal vertebral arch morphology | Cervical processes X-ray |
WTSI IMPC |
4.87×10-05 | |
Kera Keraem1(IMPC)Wtsi |
HOM | Early adult | abnormal vertebral arch morphology | Cervical processes X-ray |
WTSI IMPC |
4.87×10-05 | |
Selenok Selenoktm1b(EUCOMM)Wtsi |
HOM | Early adult | abnormal vertebral arch morphology | Cervical processes X-ray |
WTSI IMPC |
4.87×10-05 | |
Wdtc1 Wdtc1tm1a(KOMP)Wtsi |
HOM | Early adult | abnormal vertebral arch morphology | Cervical processes X-ray |
WTSI IMPC |
4.87×10-05 | |
Coa6 Coa6em1(IMPC)Ccpcz |
HET | Early adult | abnormal vertebral arch morphology | Processes on vertebrae X-ray |
CCP-IMG IMPC |
5.08×10-05 | |
Cluh Cluhem1(IMPC)Ccpcz |
HET | Early adult | abnormal vertebral arch morphology | Cervical processes X-ray |
CCP-IMG IMPC |
5.92×10-05 | |
Marveld3 Marveld3em1(IMPC)Ccpcz |
HOM | Early adult | abnormal vertebral arch morphology | Thoracic processes X-ray |
CCP-IMG IMPC |
6.20×10-05 | |
Fbxo25 Fbxo25em1(IMPC)Ccpcz |
HOM | Early adult | abnormal vertebral arch morphology | Thoracic processes X-ray |
CCP-IMG IMPC |
7.53×10-05 | |
Stk26 Stk26tm1b(EUCOMM)Hmgu |
HOM | Early adult | abnormal vertebral arch morphology | Cervical processes X-ray |
CCP-IMG IMPC |
7.68×10-05 | |
Hcar1 Hcar1em1(IMPC)Ccpcz |
HOM | Early adult | abnormal vertebral arch morphology | Cervical processes X-ray |
CCP-IMG IMPC |
8.38×10-05 | |
Wac Wactm2b(EUCOMM)Wtsi |
HET | Early adult | fusion of vertebral arches | Fusion of processes X-ray |
WTSI IMPC |
9.73×10-05 |