Phenotype: decreased heart rate variability

Definition reduced variation of beat-to-beat intervals of the heart that occurs in conjunction with the respiratory cycle

Synonyms
  • decreased respiratory sinus arrhythmia
  • decreased respiratory sinus arrhythmia
  • reduced heart rate variability
  • reduced heart rate variability

MP browserMP:0003929

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Phenotype associations stats

0.81% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased heart rate variability (13/1598)

0.81% females (13/1597) 0.82% males (13/1594)



Gene variants with decreased heart rate variability

Total number of significant genotype-phenotype associations: 26

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Sgip1
Sgip1tm1b(EUCOMM)Hmgu
HOM Female Male postnatal decreased heart rate variability Electrocardiogram (ECG) | HRV HMGU | IMPC 5.42E-11
Casq2
Casq2tm1b(KOMP)Wtsi
HET Female Male postnatal decreased heart rate variability Electrocardiogram (ECG) | HRV TCP | IMPC 2.74E-9
Gja8
Gja8tm1b(EUCOMM)Hmgu
HOM Female Male postnatal decreased heart rate variability Electrocardiogram (ECG) | HRV MRC Harwell | IMPC 3.03E-7
Trip13
Trip13tm1.1(KOMP)Vlcg
HOM Female Male postnatal decreased heart rate variability Electrocardiogram (ECG) | HRV JAX | IMPC 3.79E-6
Aif1
Aif1tm1.1(KOMP)Wtsi
HOM Female Male postnatal decreased heart rate variability Electrocardiogram (ECG) | HRV HMGU | IMPC 4.81E-6
Atrip
Atriptm1b(KOMP)Wtsi
HET Female Male postnatal decreased heart rate variability Electrocardiogram (ECG) | HRV JAX | IMPC 8.11E-6
Far2
Far2tm2b(KOMP)Wtsi
HOM Female Male postnatal decreased heart rate variability Electrocardiogram (ECG) | HRV JAX | IMPC 1.34E-5
Bbs5
Bbs5tm1b(EUCOMM)Wtsi
HOM Female Male postnatal decreased heart rate variability Electrocardiogram (ECG) | HRV MRC Harwell | IMPC 1.36E-5
Kcnh3
Kcnh3tm1.1(KOMP)Vlcg
HOM Female Male postnatal decreased heart rate variability Electrocardiogram (ECG) | HRV JAX | IMPC 5.06E-5
Lrp1
Lrp1tm1.1(KOMP)Wtsi
HET Female Male postnatal decreased heart rate variability Electrocardiogram (ECG) | HRV JAX | IMPC 5.64E-5
Vsig8
Vsig8tm1.1(KOMP)Mbp
HOM Female Male postnatal decreased heart rate variability Electrocardiogram (ECG) | HRV JAX | IMPC 8.91E-5
Dnajc5g
Dnajc5gtm1.1(KOMP)Vlcg
HOM Female Male postnatal decreased heart rate variability Electrocardiogram (ECG) | HRV JAX | IMPC 9.59E-5
Ism2
Ism2tm3b(EUCOMM)Hmgu
HOM Female Male postnatal decreased heart rate variability Electrocardiogram (ECG) | HRV BCM | IMPC 9.8E-5

Download data as: TSV XLS