Phenotype: decreased heart rate variability

Definition
reduced variation of beat-to-beat intervals of the heart that occurs in conjunction with the respiratory cycle
Synonyms
decreased respiratory sinus arrhythmia,  reduced heart rate variability
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with decreased heart rate variability

Total number of significant genotype-phenotype associations: 45

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value
Ppp2r2b
Ppp2r2btm1b(KOMP)Wtsi
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV TCP | IMPC 1.55×10-10
Sgip1
Sgip1tm1b(EUCOMM)Hmgu
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV HMGU | IMPC 3.56×10-10
Casq2
Casq2tm1b(KOMP)Wtsi
HET Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV TCP | IMPC 2.37×10-09
Gja8
Gja8tm1b(EUCOMM)Hmgu
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV MRC Harwell | IMPC 3.13×10-07
Pcyox1l
Pcyox1lem1(IMPC)J
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV JAX | IMPC 5.00×10-07
Slc44a4
Slc44a4tm1b(EUCOMM)Hmgu
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV HMGU | IMPC 9.87×10-07
Trip13
Trip13tm1.1(KOMP)Vlcg
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV JAX | IMPC 2.11×10-06
Zfp706
Zfp706em1(IMPC)J
HET Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV JAX | IMPC 6.06×10-06
Aif1
Aif1tm1.1(KOMP)Wtsi
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV HMGU | IMPC 6.08×10-06
Atrip
Atriptm1b(KOMP)Wtsi
HET Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV JAX | IMPC 6.64×10-06
Lactb
Lactbtm1.1(KOMP)Mbp
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV HMGU | IMPC 7.89×10-06
Bbs5
Bbs5tm1b(EUCOMM)Wtsi
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV MRC Harwell | IMPC 1.43×10-05
Far2
Far2tm2b(KOMP)Wtsi
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV JAX | IMPC 3.99×10-05
Kcnh3
Kcnh3tm1.1(KOMP)Vlcg
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV JAX | IMPC 4.07×10-05
Vsig8
Vsig8tm1.1(KOMP)Mbp
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV JAX | IMPC 4.10×10-05
1700086L19Rik
1700086L19Riktm1b(EUCOMM)Wtsi
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV BCM | IMPC 4.34×10-05
Edc3
Edc3em1(IMPC)Tcp
HET Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV TCP | IMPC 4.53×10-05
Lrp1
Lrp1tm1.1(KOMP)Wtsi
HET Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV JAX | IMPC 4.94×10-05
Fam161a
Fam161atm1b(KOMP)Wtsi
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV JAX | IMPC 5.26×10-05
Ism2
Ism2tm3b(EUCOMM)Hmgu
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV BCM | IMPC 5.56×10-05
Chst14
Chst14em1(IMPC)Tcp
HET Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV TCP | IMPC 8.30×10-05
Dnajc5g
Dnajc5gtm1.1(KOMP)Vlcg
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV JAX | IMPC 8.68×10-05
Eif4enif1
Eif4enif1em1(IMPC)Tcp
HET Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV TCP | IMPC 9.23×10-05
C9
C9tm1.1(KOMP)Vlcg
HOM Early adult decreased heart rate variability Electrocardiogram (ECG) | HRV JAX | IMPC 9.53×10-05

Download data as:   TSV   XLS

 The way we measure

 Phenotype associations stats

0.98% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased heart rate variability (24/2438)

0.97% females (23/2377) 0.92% males (22/2382)

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