Phenotype: abnormal neural tube closure

Definition
any anomaly in the last step in the formation of the neural tube, where the paired neural folds are brought together and fuse at the dorsal midline
Synonyms
abnormal neural fold fusion,  abnormal neural tube fusion
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with abnormal neural tube closure

Total number of significant genotype-phenotype associations: 233

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Actg1
Actg1tm1.1(KOMP)Vlcg
HET E15.5 spina bifida spina bifida
Gross Morphology Embryo E14.5-E15.5
UC Davis
IMPC
0.00
Actg1
Actg1tm1.1(KOMP)Vlcg
HOM E15.5 spina bifida spina bifida
Gross Morphology Embryo E14.5-E15.5
UC Davis
IMPC
0.00
Adar
Adartm1b(EUCOMM)Wtsi
HOM E12.5 abnormal neural tube closure Neural Tube Closure
Gross Morphology Embryo E12.5
JAX
IMPC
0.00
Afdn
Afdnem1(IMPC)Mbp
HET E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Alg10b
Alg10btm1.1(KOMP)Vlcg
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Ambra1
Ambra1em1(IMPC)Bay
HOM E12.5 abnormal neural tube closure Neural Tube Closure
Gross Morphology Embryo E12.5
BCM
IMPC
0.00
Ambra1
Ambra1em1(IMPC)Bay
HOM E15.5 spina bifida spina bifida
Gross Morphology Embryo E14.5-E15.5
BCM
IMPC
0.00
Ambra1
Ambra1em1(IMPC)Bay
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Amt
Amtem1(IMPC)Tcp
HOM E15.5 spina bifida spina bifida
Gross Morphology Embryo E14.5-E15.5
TCP
IMPC
0.00
Anapc15
Anapc15tm1.1(KOMP)Vlcg
HOM E12.5 abnormal neural tube closure Neural Tube Closure
Gross Morphology Embryo E12.5
JAX
IMPC
0.00
Ankmy2
Ankmy2em1(IMPC)Bay
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Apbb2
Apbb2tm1.1(KOMP)Vlcg
HOM E15.5 spina bifida spina bifida
Gross Morphology Embryo E14.5-E15.5
UC Davis
IMPC
0.00
Apbb2
Apbb2tm1.1(KOMP)Vlcg
HET E15.5 spina bifida spina bifida
Gross Morphology Embryo E14.5-E15.5
UC Davis
IMPC
0.00
Arpc1a
Arpc1aem1(IMPC)J
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
JAX
IMPC
0.00
Asf1a
Asf1atm1b(KOMP)Wtsi
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
JAX
IMPC
0.00
Atp1b1
Atp1b1em1(IMPC)Mbp
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Atp1b3
Atp1b3em1(IMPC)Bay
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Bbox1
Bbox1tm1b(KOMP)Wtsi
HOM E12.5 abnormal neural tube closure Neural Tube Closure
Gross Morphology Embryo E12.5
BCM
IMPC
0.00
Bmp4
Bmp4tm1b(EUCOMM)Hmgu
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Brap
Brapem1(IMPC)Mbp
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Cdk8
Cdk8tm1b(EUCOMM)Hmgu
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
ICS
IMPC
0.00
Cecr2
Cecr2tm2b(EUCOMM)Hmgu
HET E12.5 abnormal neural tube closure Neural Tube Closure
Gross Morphology Embryo E12.5
TCP
IMPC
0.00
Cecr2
Cecr2tm2b(EUCOMM)Hmgu
HOM E12.5 abnormal neural tube closure Neural Tube Closure
Gross Morphology Embryo E12.5
TCP
IMPC
0.00
Cep97
Cep97tm1.1(KOMP)Vlcg
HET E15.5 spina bifida spina bifida
Gross Morphology Embryo E14.5-E15.5
UC Davis
IMPC
0.00
Cep97
Cep97tm1.1(KOMP)Vlcg
HOM E15.5 spina bifida spina bifida
Gross Morphology Embryo E14.5-E15.5
UC Davis
IMPC
0.00
Cgn
Cgntm1b(KOMP)Wtsi
HOM E12.5 abnormal neural tube closure Neural Tube Closure
Gross Morphology Embryo E12.5
JAX
IMPC
0.00
Chchd1
Chchd1tm1.1(KOMP)Vlcg
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
TCP
IMPC
0.00
Cnnm2
Cnnm2tm1.1(KOMP)Vlcg
HET E15.5 spina bifida spina bifida
Gross Morphology Embryo E14.5-E15.5
UC Davis
IMPC
0.00
Cnnm2
Cnnm2tm1.1(KOMP)Vlcg
HOM E15.5 spina bifida spina bifida
Gross Morphology Embryo E14.5-E15.5
UC Davis
IMPC
0.00
Cox18
Cox18em1(IMPC)J
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
JAX
IMPC
0.00
Csk
Csktm2b(EUCOMM)Hmgu
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Cwc22
Cwc22em1(IMPC)Mbp
HET E15.5 spina bifida spina bifida
Gross Morphology Embryo E14.5-E15.5
UC Davis
IMPC
0.00
Dennd1a
Dennd1aem1(IMPC)Mbp
HET E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Dennd1a
Dennd1aem1(IMPC)Mbp
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Dhx29
Dhx29tm1.1(KOMP)Vlcg
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
JAX
IMPC
0.00
Dlg5
Dlg5tm1b(EUCOMM)Wtsi
HOM E15.5 spina bifida spina bifida
Gross Morphology Embryo E14.5-E15.5
UC Davis
IMPC
0.00
Dlg5
Dlg5tm1b(EUCOMM)Wtsi
HET E15.5 spina bifida spina bifida
Gross Morphology Embryo E14.5-E15.5
UC Davis
IMPC
0.00
Dnm1
Dnm1tm1.1(KOMP)Vlcg
HET E15.5 spina bifida spina bifida
Gross Morphology Embryo E14.5-E15.5
UC Davis
IMPC
0.00
Dnm1
Dnm1tm1.1(KOMP)Vlcg
HOM E15.5 spina bifida spina bifida
Gross Morphology Embryo E14.5-E15.5
UC Davis
IMPC
0.00
Dsp
Dspem1(IMPC)Mbp
HET E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Egr1
Egr1tm1b(NCOM)Mfgc
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
TCP
IMPC
0.00
Fadd
Faddtm1e.1(KOMP)Wtsi
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
TCP
IMPC
0.00
Faf2
Faf2em1(IMPC)Mbp
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Fhod3
Fhod3em1(IMPC)Mbp
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Fhod3
Fhod3em1(IMPC)Mbp
HET E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Fuz
Fuzem1(IMPC)Mbp
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Gabpa
Gabpaem2(IMPC)Mbp
HET E15.5 spina bifida spina bifida
Gross Morphology Embryo E14.5-E15.5
UC Davis
IMPC
0.00
Gabpa
Gabpaem2(IMPC)Mbp
HOM E15.5 spina bifida spina bifida
Gross Morphology Embryo E14.5-E15.5
UC Davis
IMPC
0.00
Glmn
Glmnem1(IMPC)Bay
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Got2
Got2em1(IMPC)Mbp
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Greb1l
Greb1lem1(IMPC)J
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
JAX
IMPC
0.00
Grhl2
Grhl2em1(IMPC)Mbp
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Hibch
Hibchem1(IMPC)Tcp
HET E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
TCP
IMPC
0.00
Hibch
Hibchem1(IMPC)Tcp
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
TCP
IMPC
0.00
Ift172
Ift172tm2b(EUCOMM)Hmgu
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Ift43
Ift43tm1b(EUCOMM)Hmgu
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Inpp5e
Inpp5etm1.1(KOMP)Vlcg
HOM E12.5 abnormal neural tube closure Neural Tube Closure
Gross Morphology Embryo E12.5
TCP
IMPC
0.00
Ints10
Ints10tm1b(KOMP)Wtsi
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
JAX
IMPC
0.00
Ipo9
Ipo9em1(IMPC)Bay
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Isyna1
Isyna1em1(IMPC)Bay
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Junb
Junbtm1b(EUCOMM)Hmgu
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Krit1
Krit1tm1.1(KOMP)Vlcg
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Krt14
Krt14tm1.1(KOMP)Vlcg
HET E15.5 spina bifida spina bifida
Gross Morphology Embryo E14.5-E15.5
UC Davis
IMPC
0.00
Krt14
Krt14tm1.1(KOMP)Vlcg
HOM E15.5 spina bifida spina bifida
Gross Morphology Embryo E14.5-E15.5
UC Davis
IMPC
0.00
Laptm4b
Laptm4btm1e.1(KOMP)Wtsi
HOM E12.5 abnormal neural tube closure Neural Tube Closure
Gross Morphology Embryo E12.5
TCP
IMPC
0.00
Mbd6
Mbd6tm1.1(KOMP)Vlcg
HOM E15.5 spina bifida spina bifida
Gross Morphology Embryo E14.5-E15.5
UC Davis
IMPC
0.00
Mbd6
Mbd6tm1.1(KOMP)Vlcg
HET E15.5 spina bifida spina bifida
Gross Morphology Embryo E14.5-E15.5
UC Davis
IMPC
0.00
Mdh2
Mdh2em1(IMPC)Bay
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Myb
Mybtm1b(KOMP)Wtsi
HOM E15.5 spina bifida spina bifida
Gross Morphology Embryo E14.5-E15.5
UC Davis
IMPC
0.00
Myb
Mybtm1b(KOMP)Wtsi
HET E15.5 spina bifida spina bifida
Gross Morphology Embryo E14.5-E15.5
UC Davis
IMPC
0.00
Nalcn
Nalcnem1(IMPC)Mbp
HOM E15.5 spina bifida spina bifida
Gross Morphology Embryo E14.5-E15.5
UC Davis
IMPC
0.00
Nalcn
Nalcnem1(IMPC)Mbp
HET E15.5 spina bifida spina bifida
Gross Morphology Embryo E14.5-E15.5
UC Davis
IMPC
0.00
Ndufb5
Ndufb5em1(IMPC)Bay
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Nog
Nogem1(IMPC)Mbp
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Nr6a1
Nr6a1tm1b(EUCOMM)Wtsi
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Nsmce2
Nsmce2em1(IMPC)Bay
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Nufip2
Nufip2em1(IMPC)J
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
JAX
IMPC
0.00
Opa1
Opa1em1(IMPC)Bay
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Pccb
Pccbtm1.1(KOMP)Vlcg
HOM E15.5 spina bifida spina bifida
Gross Morphology Embryo E14.5-E15.5
UC Davis
IMPC
0.00
Pccb
Pccbtm1.1(KOMP)Vlcg
HET E15.5 spina bifida spina bifida
Gross Morphology Embryo E14.5-E15.5
UC Davis
IMPC
0.00
Pcgf1
Pcgf1tm1.1(KOMP)Vlcg
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
JAX
IMPC
0.00
Pcnp
Pcnpem1(IMPC)Mbp
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Pcsk5
Pcsk5tm1b(KOMP)Mbp
HOM E12.5 abnormal neural tube closure Neural Tube Closure
Gross Morphology Embryo E12.5
JAX
IMPC
0.00
Pibf1
Pibf1tm1.1(KOMP)Vlcg
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
JAX
IMPC
0.00
Pigq
Pigqtm2b(EUCOMM)Wtsi
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Pkmyt1
Pkmyt1em1(IMPC)J
HOM E12.5 abnormal neural tube closure Neural Tube Closure
Gross Morphology Embryo E12.5
JAX
IMPC
0.00
Pole2
Pole2em1(IMPC)Mbp
HET E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Prrc2c
Prrc2cem1(IMPC)J
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
JAX
IMPC
0.00
Psmg1
Psmg1tm1b(KOMP)Wtsi
HET E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Pygo2
Pygo2tm1b(EUCOMM)Wtsi
HOM E12.5 abnormal neural tube closure Neural Tube Closure
Gross Morphology Embryo E12.5
TCP
IMPC
0.00
Rad9a
Rad9atm1.1(KOMP)Wtsi
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Ranbp1
Ranbp1tm1b(KOMP)Wtsi
HOM E12.5 abnormal neural tube closure Neural Tube Closure
Gross Morphology Embryo E12.5
TCP
IMPC
0.00
Rbbp4
Rbbp4em1(IMPC)Mbp
HET E15.5 spina bifida spina bifida
Gross Morphology Embryo E14.5-E15.5
UC Davis
IMPC
0.00
Rbm22
Rbm22em1(IMPC)Mbp
HET E15.5 spina bifida spina bifida
Gross Morphology Embryo E14.5-E15.5
UC Davis
IMPC
0.00
Rgl1
Rgl1em1(IMPC)Mbp
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Scrib
Scribtm1b(NCOM)Mfgc
HOM E12.5 abnormal neural tube closure Neural Tube Closure
Gross Morphology Embryo E12.5
TCP
IMPC
0.00
Scrib
Scribtm1b(NCOM)Mfgc
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
TCP
IMPC
0.00
Sfmbt2
Sfmbt2em1(IMPC)Mbp
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Shroom3
Shroom3em1(IMPC)Bay
HOM E18.5 spina bifida spina bifida
Gross Morphology Embryo E18.5
BCM
IMPC
0.00
Slc25a1
Slc25a1tm1b(EUCOMM)Wtsi
HOM E12.5 abnormal neural tube closure Neural Tube Closure
Gross Morphology Embryo E12.5
BCM
IMPC
0.00
Slc30a9
Slc30a9em1(IMPC)Bay
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Slc35b4
Slc35b4tm1.1(KOMP)Vlcg
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
TCP
IMPC
0.00
Slc39a4
Slc39a4tm1.1(KOMP)Wtsi
HET E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
TCP
IMPC
0.00
Smg5
Smg5em1(IMPC)Mbp
HET E15.5 spina bifida spina bifida
Gross Morphology Embryo E14.5-E15.5
UC Davis
IMPC
0.00
Snai2
Snai2tm1.1(KOMP)Vlcg
HET E15.5 spina bifida spina bifida
Gross Morphology Embryo E14.5-E15.5
UC Davis
IMPC
0.00
Snx3
Snx3tm1.1(KOMP)Vlcg
HOM E12.5 abnormal neural tube closure Neural Tube Closure
Gross Morphology Embryo E12.5
JAX
IMPC
0.00
Snx3
Snx3tm1.1(KOMP)Vlcg
HOM E15.5 spina bifida spina bifida
Gross Morphology Embryo E14.5-E15.5
JAX
IMPC
0.00
Sox4
Sox4em1(IMPC)Mbp
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Sptan1
Sptan1em1(IMPC)Mbp
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Sufu
Sufutm1b(KOMP)Wtsi
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
TCP
IMPC
0.00
Taf12
Taf12em1(IMPC)Mbp
HET E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Tbr1
Tbr1tm1.1(KOMP)Mbp
HOM E15.5 spina bifida spina bifida
Gross Morphology Embryo E14.5-E15.5
UC Davis
IMPC
0.00
Tbr1
Tbr1tm1.1(KOMP)Mbp
HET E15.5 spina bifida spina bifida
Gross Morphology Embryo E14.5-E15.5
UC Davis
IMPC
0.00
Tbx20
Tbx20em1(IMPC)Mbp
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Tctn1
Tctn1em1(IMPC)Mbp
HOM E15.5 spina bifida spina bifida
Gross Morphology Embryo E14.5-E15.5
UC Davis
IMPC
0.00
Tctn1
Tctn1em1(IMPC)Mbp
HET E15.5 spina bifida spina bifida
Gross Morphology Embryo E14.5-E15.5
UC Davis
IMPC
0.00
Tmem132a
Tmem132atm1b(KOMP)Wtsi
HOM E12.5 abnormal neural tube closure Neural Tube Closure
Gross Morphology Embryo E12.5
BCM
IMPC
0.00
Tmem132a
Tmem132atm1b(KOMP)Wtsi
HOM E15.5 spina bifida spina bifida
Gross Morphology Embryo E14.5-E15.5
BCM
IMPC
0.00
Tmem132a
Tmem132atm1b(KOMP)Wtsi
HOM E18.5 spina bifida spina bifida
Gross Morphology Embryo E18.5
BCM
IMPC
0.00
Ubc
Ubcem1(IMPC)Mbp
HET E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Ubr2
Ubr2tm1e.1(KOMP)Mbp
HOM E15.5 spina bifida spina bifida
Gross Morphology Embryo E14.5-E15.5
UC Davis
IMPC
0.00
Ubr2
Ubr2tm1e.1(KOMP)Mbp
HET E15.5 spina bifida spina bifida
Gross Morphology Embryo E14.5-E15.5
UC Davis
IMPC
0.00
Ufsp2
Ufsp2em1(IMPC)Mbp
HET E15.5 spina bifida spina bifida
Gross Morphology Embryo E14.5-E15.5
UC Davis
IMPC
0.00
Uggt1
Uggt1em1(IMPC)Mbp
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
UC Davis
IMPC
0.00
Uqcc3
Uqcc3em1(IMPC)Bay
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
BCM
IMPC
0.00
Utp4
Utp4em1(IMPC)J
HET E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
JAX
IMPC
0.00
Xpo1
Xpo1em1(IMPC)Mbp
HET E15.5 spina bifida spina bifida
Gross Morphology Embryo E14.5-E15.5
UC Davis
IMPC
0.00
Xpo5
Xpo5em1(IMPC)Mbp
HET E15.5 spina bifida spina bifida
Gross Morphology Embryo E14.5-E15.5
UC Davis
IMPC
0.00
Zc3h11a
Zc3h11aem1(IMPC)Mbp
HET E15.5 spina bifida spina bifida
Gross Morphology Embryo E14.5-E15.5
UC Davis
IMPC
0.00
Zc3h4
Zc3h4em1(IMPC)Mbp
HET E15.5 spina bifida spina bifida
Gross Morphology Embryo E14.5-E15.5
UC Davis
IMPC
0.00
Zmym2
Zmym2em1(IMPC)Bay
HOM E9.5 abnormal neural tube closure Neural tube closure
Gross Morphology Embryo E9.5
BCM
IMPC
0.00

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 The way we measure

 Phenotype associations stats

7.31% of tested genes with null mutations on a B6N genetic background have a phenotype association to abnormal neural tube closure (106/1450)

7.55% females (93/1232) 7.44% males (91/1223)

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