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Phenotype: abnormal forebrain development

Definition
anomaly in the formation or patterning of the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions)
Synonyms
abnormal prosencephalon development
Significant gene associations The way we measure Phenotype stats
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with abnormal forebrain development

Total number of significant genotype-phenotype associations: 83

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center		 P Value
Actr5
Actr5tm2b(EUCOMM)Wtsi 		HOM E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 BCM
IMPC		 0.00
Alg10b
Alg10btm1.1(KOMP)Vlcg 		HOM E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 BCM
IMPC		 0.00
Ankmy2
Ankmy2em1(IMPC)Bay 		HOM E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 BCM
IMPC		 0.00
Atp1b3
Atp1b3em1(IMPC)Bay 		HOM E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 BCM
IMPC		 0.00
Bmp4
Bmp4tm1b(EUCOMM)Hmgu 		HOM E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 BCM
IMPC		 0.00
Chchd1
Chchd1tm1.1(KOMP)Vlcg 		HOM E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 TCP
IMPC		 0.00
Coq6
Coq6tm1b(EUCOMM)Hmgu 		HOM E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 JAX
IMPC		 0.00
Dennd1a
Dennd1aem1(IMPC)Mbp 		HOM E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 UC Davis
IMPC		 0.00
Egr1
Egr1tm1b(NCOM)Mfgc 		HOM E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 TCP
IMPC		 0.00
Faf2
Faf2em1(IMPC)Mbp 		HOM E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 UC Davis
IMPC		 0.00
Fhod3
Fhod3em1(IMPC)Mbp 		HOM E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 UC Davis
IMPC		 0.00
Glmn
Glmnem1(IMPC)Bay 		HOM E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 BCM
IMPC		 0.00
Gnb1l
Gnb1lem1(IMPC)Tcp 		HET E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 TCP
IMPC		 0.00
Got2
Got2em1(IMPC)Mbp 		HOM E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 UC Davis
IMPC		 0.00
Grhl2
Grhl2em1(IMPC)Mbp 		HOM E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 UC Davis
IMPC		 0.00
Gxylt1
Gxylt1em1(IMPC)Bay 		HOM E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 BCM
IMPC		 0.00
Hibch
Hibchem1(IMPC)Tcp 		HET E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 TCP
IMPC		 0.00
Hibch
Hibchem1(IMPC)Tcp 		HOM E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 TCP
IMPC		 0.00
Ift43
Ift43tm1b(EUCOMM)Hmgu 		HOM E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 BCM
IMPC		 0.00
Ift52
Ift52em1(IMPC)Bay 		HOM E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 BCM
IMPC		 0.00
Ipo9
Ipo9em1(IMPC)Bay 		HOM E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 BCM
IMPC		 0.00
Junb
Junbtm1b(EUCOMM)Hmgu 		HOM E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 BCM
IMPC		 0.00
Mdh2
Mdh2em1(IMPC)Bay 		HOM E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 BCM
IMPC		 0.00
Ndufaf8
Ndufaf8em1(IMPC)Bay 		HOM E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 BCM
IMPC		 0.00
Ndufb5
Ndufb5em1(IMPC)Bay 		HOM E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 BCM
IMPC		 0.00
Nog
Nogem1(IMPC)Mbp 		HOM E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 UC Davis
IMPC		 0.00
Nr6a1
Nr6a1tm1b(EUCOMM)Wtsi 		HOM E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 BCM
IMPC		 0.00
Nsmce2
Nsmce2em1(IMPC)Bay 		HOM E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 BCM
IMPC		 0.00
Opa1
Opa1em1(IMPC)Bay 		HOM E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 BCM
IMPC		 0.00
Pcgf1
Pcgf1tm1.1(KOMP)Vlcg 		HOM E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 JAX
IMPC		 0.00
Pcnp
Pcnpem1(IMPC)Mbp 		HOM E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 UC Davis
IMPC		 0.00
Pdhb
Pdhbem1(IMPC)Bay 		HOM E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 BCM
IMPC		 0.00
Pgm1
Pgm1em1(IMPC)Bay 		HOM E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 BCM
IMPC		 0.00
Pigq
Pigqtm2b(EUCOMM)Wtsi 		HOM E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 BCM
IMPC		 0.00
Ppp1r35
Ppp1r35tm1.1(KOMP)Vlcg 		HOM E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 JAX
IMPC		 0.00
Rad9a
Rad9atm1.1(KOMP)Wtsi 		HOM E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 BCM
IMPC		 0.00
Slc30a9
Slc30a9em1(IMPC)Bay 		HOM E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 BCM
IMPC		 0.00
Slc35b4
Slc35b4tm1.1(KOMP)Vlcg 		HOM E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 TCP
IMPC		 0.00
Slc39a4
Slc39a4tm1.1(KOMP)Wtsi 		HET E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 TCP
IMPC		 0.00
Sptan1
Sptan1em1(IMPC)Mbp 		HOM E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 UC Davis
IMPC		 0.00
Sufu
Sufutm1b(KOMP)Wtsi 		HOM E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 TCP
IMPC		 0.00
Tbx20
Tbx20em1(IMPC)Mbp 		HOM E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 UC Davis
IMPC		 0.00
Tiprl
Tiprltm1.1(KOMP)Vlcg 		HOM E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 JAX
IMPC		 0.00
Uqcc3
Uqcc3em1(IMPC)Bay 		HOM E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 BCM
IMPC		 0.00
Vps29
Vps29em1(IMPC)Bay 		HET E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 BCM
IMPC		 0.00
Zmym2
Zmym2em1(IMPC)J 		HOM E9.5 abnormal forebrain development Forebrain
Gross Morphology Embryo E9.5		 JAX
IMPC		 0.00

Download data as:   TSV   XLS

 The way we measure

Procedure
Gross Morphology Embryo E12.5
Gross Morphology Embryo E9.5

 Phenotype associations stats

5.08% of tested genes with null mutations on a B6N genetic background have a phenotype association to abnormal forebrain development (45/885)

4.52% females (40/884) 4.53% males (40/883)

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